{"id":34147,"date":"2024-11-30T23:56:47","date_gmt":"2024-11-30T15:56:47","guid":{"rendered":"https:\/\/17aitech.com\/?p=34147"},"modified":"2024-11-30T23:56:47","modified_gmt":"2024-11-30T15:56:47","slug":"%e3%80%8c%e5%a4%8d%e6%b4%bb%e3%80%8d%e5%8f%a4%e7%94%9f%e7%89%a9%e5%88%86%e5%ad%90%ef%bc%8cai%e8%a7%a3%e5%86%b3%e6%8a%97%e7%94%9f%e7%b4%a0%e8%80%90%e8%8d%af%e6%80%a7%ef%bc%8c%e5%a4%8d%e6%97%a6%e3%80%81","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=34147","title":{"rendered":"\u300c\u590d\u6d3b\u300d\u53e4\u751f\u7269\u5206\u5b50\uff0cAI\u89e3\u51b3\u6297\u751f\u7d20\u8010\u836f\u6027\uff0c\u590d\u65e6\u3001\u5bbe\u5927\u5408\u4f5c\u56e2\u961f\u4e24\u7bc7\u8bba\u6587\u767bCell\u548cNature\u5b50\u520a"},"content":{"rendered":"

\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:\u300c\u590d\u6d3b\u300d\u53e4\u751f\u7269\u5206\u5b50\uff0cAI\u89e3\u51b3\u6297\u751f\u7d20\u8010\u836f\u6027\uff0c\u590d\u65e6\u3001\u5bbe\u5927\u5408\u4f5c\u56e2\u961f\u4e24\u7bc7\u8bba\u6587\u767bCell\u548cNature\u5b50\u520a<\/a><\/p>\n

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\u7f16\u8f91 | \u841d\u535c\u76ae<\/p>\n

\u6297\u751f\u7d20\u8010\u836f\u6027\u611f\u67d3\u6bcf\u5e74\u5728\u5168\u7403\u9020\u6210\u7ea6 127 \u4e07\u4eba\u6b7b\u4ea1\uff0c\u9884\u8ba1\u5230 2050 \u5e74\uff0c\u5982\u679c\u6ca1\u6709\u7279\u6548\u7684\u65b0\u836f\uff0c\u6bcf\u5e74\u6b7b\u4ea1\u4eba\u6570\u5c06\u8fbe\u5230 1000 \u4e07\u4eba\uff0c\u56e0\u6b64\u9700\u8981\u91c7\u53d6\u7d27\u6025\u63aa\u65bd\u6765\u5e94\u5bf9\u6297\u751f\u7d20\u8010\u836f\u6027\u3002<\/p>\n

\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u7684\u6821\u957f\u52a9\u7406\u6559\u6388\uff08Presidential Assistant Professor\uff09 Cesar de la Fuente \u8bf4\uff1a\u300c\u5373\u4f7f\u611f\u89c9\u8eab\u4f53\u597d\u4e9b\u4e86\uff0c\u4e5f\u8981\u786e\u4fdd\u5b8c\u6210\u6297\u751f\u7d20\u7597\u7a0b\uff0c\u8fd9\u662f\u8bb8\u591a\u4eba\u542c\u8fc7\uff0c\u4f46\u7ecf\u5e38\u5ffd\u89c6\u7684\u533b\u5b66\u53e3\u5934\u7985\u3002\u300d<\/p>\n

\u4ed6\u89e3\u91ca\u9053\uff0c\u8fd9\u53e5\u8bdd\u81f3\u5173\u91cd\u8981\uff0c\u4e0d\u9075\u5b88\u89c4\u5b9a\u53ef\u80fd\u4f1a\u5f71\u54cd\u6297\u751f\u7d20\u7684\u4f7f\u7528\u529f\u6548\u3002\u300c\u8fd1\u51e0\u5341\u5e74\u6765\uff0c\u8fd9\u5bfc\u81f4\u4e86\u8010\u836f\u7ec6\u83cc\u7684\u589e\u52a0\uff0c\u5168\u7403\u5065\u5eb7\u5371\u673a\u65e5\u76ca\u4e25\u91cd\uff0c\u6bcf\u5e74\u9020\u6210\u7ea6 495 \u4e07\u4eba\u6b7b\u4ea1\uff0c\u751a\u81f3\u53ef\u80fd\u4f7f\u666e\u901a\u611f\u67d3\u4e5f\u81f4\u547d\u3002\u300d<\/p>\n

De la Fuente \u548c\u590d\u65e6\u5927\u5b66<\/mark>\u3001\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u7684\u7814\u7a76\u4eba\u5458\u7ec4\u6210\u7684\u8de8\u5b66\u79d1\u7814\u7a76\u56e2\u961f\uff0c\u4e00\u76f4\u81f4\u529b\u4e8e\u7814\u7a76\u5e94\u5bf9\u6297\u751f\u7d20\u8010\u836f\u6027\u95ee\u9898\u3002<\/p>\n

\u5728\u4e00\u9879\u53d1\u8868\u7684\u65b0\u7814\u7a76\u4e2d\uff0c\u4ed6\u4eec\u5f00\u53d1\u4e86\u4e00\u79cd\u4eba\u5de5\u667a\u80fd<\/mark>\u5de5\u5177\u6765\u6316\u6398\u5e9e\u5927\u4e14\u57fa\u672c\u4e0a\u672a\u5f00\u53d1\u7684\u751f\u7269\u6570\u636e\u2014\u2014\u8d85\u8fc7 1000 \u4e07\u4e2a\u73b0\u4ee3\u548c\u5df2\u706d\u7edd\u751f\u7269\u7684\u5206\u5b50\u2014\u2014\u4ee5\u53d1\u73b0\u65b0\u7684\u6297\u751f\u7d20\u5019\u9009\u836f\u7269\u3002<\/p>\n

\u8be5\u7814\u7a76\u4ee5\u300cDeep-learning-enabled antibiotic discovery through molecular de-extinction<\/em>\u300d\u4e3a\u9898\uff0c\u4e8e 2024 \u5e74 6 \u6708 11 \u65e5\u53d1\u5e03\u5728\u300aNature Biomedical Engineering<\/em>\u300b\u3002<\/p>\n

<\/a><\/p>\n

\u8bba\u6587\u94fe\u63a5\uff1ahttps:\/\/www.nature.com\/articles\/s41551-024-01201-x<\/em><\/section>\n

\u300c\u91c7\u7528\u4f20\u7edf\u65b9\u6cd5\uff0c\u5f00\u53d1\u6cbb\u7597\u611f\u67d3\u7684\u65b0\u578b\u4e34\u5e8a\u524d\u5019\u9009\u836f\u7269\u5927\u7ea6\u9700\u8981\u516d\u5e74\u65f6\u95f4\uff0c\u8fd9\u4e2a\u8fc7\u7a0b\u975e\u5e38\u8270\u82e6\u4e14\u6602\u8d35\u3002\u300dDe la Fuente \u8bf4\u3002<\/p>\n

\u300c\u6211\u4eec\u7684\u6df1\u5ea6\u5b66\u4e60<\/mark>\u65b9\u6cd5\u53ef\u4ee5\u5927\u5927\u7f29\u77ed\u65f6\u95f4\uff0c\u964d\u4f4e\u6210\u672c\uff0c\u56e0\u4e3a\u6211\u4eec\u5728\u77ed\u77ed\u51e0\u4e2a\u5c0f\u65f6\u5185\u5c31\u786e\u5b9a\u4e86\u6570\u5343\u79cd\u5019\u9009\u836f\u7269\uff0c\u800c\u4e14\u5176\u4e2d\u8bb8\u591a\u836f\u7269\u5177\u6709\u4e34\u5e8a\u524d\u6f5c\u529b\uff0c\u8fd9\u5728\u6211\u4eec\u7684\u52a8\u7269\u6a21\u578b\u4e2d\u8fdb\u884c\u4e86\u6d4b\u8bd5\uff0c\u6807\u5fd7\u7740\u6297\u751f\u7d20\u53d1\u73b0\u7684\u65b0\u65f6\u4ee3\u7684\u5f00\u59cb\u3002\u300d<\/p>\n

\u6700\u65b0\u53d1\u73b0\u5efa\u7acb\u5728 De la Fuente \u81ea 2019 \u5e74\u6765\u5230\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u4ee5\u6765\u4e00\u76f4\u7814\u7a76\u7684\u65b9\u6cd5\u7684\u57fa\u7840\u4e0a\u3002\u8be5\u56e2\u961f\u63d0\u51fa\u4e86\u4e00\u4e2a\u57fa\u672c\u95ee\u9898\uff1a\u80fd\u5426\u5229\u7528\u673a\u5668\u901a\u8fc7\u6316\u6398\u5168\u7403\u751f\u7269\u4fe1\u606f\u6765\u52a0\u901f\u6297\u751f\u7d20\u7684\u53d1\u73b0\uff1f<\/p>\n

\u4ed6\u89e3\u91ca\u8bf4\uff0c\u8fd9\u4e2a\u60f3\u6cd5\u57fa\u4e8e\u8fd9\u6837\u7684\u89c2\u5ff5\uff1a\u751f\u7269\u5b66\u4ece\u6700\u57fa\u672c\u7684\u5c42\u9762\u4e0a\u6765\u8bf4\u662f\u4e00\u4e2a\u4fe1\u606f\u6765\u6e90\uff0c\u7406\u8bba\u4e0a\u53ef\u4ee5\u5229\u7528\u4eba\u5de5\u667a\u80fd<\/mark>\u8fdb\u884c\u63a2\u7d22\uff0c\u4ee5\u5bfb\u627e\u65b0\u7684\u6709\u7528\u5206\u5b50\u3002<\/p>\n

\u8be5\u56e2\u961f\u9996\u5148\u5e94\u7528\u7b80\u5355\u7684\u7b97\u6cd5\u6765\u6316\u6398\u5355\u4e2a\u86cb\u767d\u8d28\uff0c\u4ee5\u627e\u5230\u9690\u85cf\u5728\u5176\u6c28\u57fa\u9178\u5e8f\u5217\u4e2d\u7684\u5c0f\u6297\u751f\u7d20\u5206\u5b50\u3002\u968f\u7740\u8ba1\u7b97\u80fd\u529b\u7684\u8fdb\u6b65\uff0cDe la Fuente \u610f\u8bc6\u5230\u4ed6\u4eec\u53ef\u4ee5\u5c06\u6316\u6398\u5355\u4e2a\u86cb\u767d\u8d28\u6269\u5c55\u5230\u6316\u6398\u6574\u4e2a\u86cb\u767d\u8d28\u7ec4\u3002<\/p>\n

\u4ed6\u8bf4\uff0c\u4ed6\u4eec\u80fd\u591f\u6316\u6398\u300c\u6574\u4e2a\u86cb\u767d\u8d28\u7ec4\uff0c\u5373\u751f\u7269\u4f53\u57fa\u56e0\u7ec4\u4e2d\u7f16\u7801\u7684\u6240\u6709\u86cb\u767d\u8d28\uff0c\u8fd9\u4f7f\u6211\u4eec\u5728\u4eba\u7c7b\u86cb\u767d\u8d28\u7ec4\u4e2d\u53d1\u73b0\u4e86\u6570\u5343\u79cd\u65b0\u7684\u6297\u83cc\u5206\u5b50\uff0c\u540e\u6765\u53c8\u5728\u5c3c\u5b89\u5fb7\u7279\u4eba\u548c\u4e39\u5c3c\u7d22\u74e6\u4eba\u7b49\u53e4\u4ee3\u7c7b\u4eba\u733f\u7684\u86cb\u767d\u8d28\u7ec4\u4e2d\u53d1\u73b0\u4e86\u6570\u5343\u79cd\u65b0\u7684\u6297\u83cc\u5206\u5b50\u3002<\/p>\n

\u300c\u7136\u540e\uff0c\u6211\u4eec\u6311\u6218\u81ea\u5df1\uff0c\u6316\u6398\u79d1\u5b66\u754c\u5df2\u77e5\u7684\u6240\u6709\u706d\u7edd\u751f\u7269\u3002\u300d\u4ed6\u8bf4\u3002<\/p>\n

\u300c\u5206\u5b50\u590d\u6d3b\u300d\u6280\u672f<\/strong><\/p>\n

De la Fuente \u56e2\u961f\u5f00\u53d1\u51fa\u4e86\u6240\u8c13\u7684\u300c\u5206\u5b50\u590d\u6d3b\u300d\u6280\u672f\uff0c\u5373\u590d\u6d3b\u5df2\u7ecf\u706d\u7edd\u7684\u5177\u6709\u6f5c\u5728\u6cbb\u7597\u4f5c\u7528\u7684\u53e4\u4ee3\u5206\u5b50\uff0c\u5e76\u56e0\u6b64\u5728\u53e4\u4ee3\u751f\u7269\u7684\u57fa\u56e0\u7ec4\u4e2d\u53d1\u73b0\u4e86\u6cbb\u7597\u5206\u5b50\u3002\u4ed6\u4eec\u63a8\u6d4b\uff0c\u4ed6\u4eec\u53d1\u73b0\u7684\u8bb8\u591a\u5206\u5b50\u53ef\u80fd\u5728\u6574\u4e2a\u8fdb\u5316\u8fc7\u7a0b\u4e2d\u4e3a\u5bbf\u4e3b\u7684\u514d\u75ab\u53d1\u6325\u4f5c\u7528\u3002<\/p>\n

\u8be5\u7814\u7a76\u4ee5\u300cDiscovery of antimicrobial peptides in the global microbiome with machine learning<\/em>\u300d\u4e3a\u9898\uff0c\u4e8e 2024 \u5e74 6 \u6708 5 \u65e5\u53d1\u5e03\u5728\u300aCell<\/em>\u300b\u3002<\/p>\n

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\u8bba\u6587\u94fe\u63a5\uff1ahttps:\/\/doi.org\/10.1016\/j.cell.2024.05.013<\/em><\/section>\n

\u7814\u7a76\u4eba\u5458\u5728\u300aCell<\/em>\u300b\u7684\u8fd9\u9879\u7814\u7a76\u4e2d\u63d0\u51fa\u4e86\u4e00\u79cd\u57fa\u4e8e\u673a\u5668\u5b66\u4e60<\/mark>\u7684\u65b9\u6cd5\uff0c\u6765\u9884\u6d4b\u5168\u7403\u5fae\u751f\u7269\u7ec4\u4e2d\u7684\u6297\u83cc\u80bd (AMP)\uff0c\u5e76\u5229\u7528\u6765\u81ea\u73af\u5883\u548c\u5bbf\u4e3b\u76f8\u5173\u6816\u606f\u5730\u7684 63,410 \u4e2a\u5b8f\u57fa\u56e0\u7ec4\u548c 87,920 \u4e2a\u539f\u6838\u751f\u7269\u57fa\u56e0\u7ec4\u7684\u5e9e\u5927\u6570\u636e\u96c6\u6765\u521b\u5efa AMPSphere\uff0c\u8fd9\u662f\u4e00\u4e2a\u5305\u542b 863,498 \u79cd\u975e\u5197\u4f59\u80bd\u7684\u7efc\u5408\u76ee\u5f55\uff0c\u5176\u4e2d\u5f88\u5c11\u6709\u4e0e\u73b0\u6709\u6570\u636e\u5e93<\/mark>\u5339\u914d\u7684\u80bd\u3002<\/p>\n

AMPSphere \u63d0\u4f9b\u4e86\u80bd\u8fdb\u5316\u8d77\u6e90\u7684\u89c1\u89e3\uff0c\u5305\u62ec\u901a\u8fc7\u590d\u5236\u6216\u8f83\u957f\u5e8f\u5217\u7684\u57fa\u56e0\u622a\u65ad\uff0c\u7814\u7a76\u4eba\u5458\u89c2\u5bdf\u5230 AMP \u7684\u4ea7\u751f\u56e0\u6816\u606f\u5730\u800c\u5f02\u3002<\/p>\n

\u4e3a\u4e86\u9a8c\u8bc1\u9884\u6d4b\uff0c\u7814\u7a76\u4eba\u5458\u5408\u6210\u4e86 100 \u79cd AMP\uff0c\u5e76\u5728\u4f53\u5916\u548c\u4f53\u5185\u6d4b\u8bd5\u4e86\u5b83\u4eec\u5bf9\u4e34\u5e8a\u76f8\u5173\u7684\u8010\u836f\u75c5\u539f\u4f53\u548c\u4eba\u7c7b\u80a0\u9053\u5171\u751f\u83cc\u7684\u4f5c\u7528\u3002<\/p>\n

<\/a><\/p>\n

\u603b\u5171\u6709 79 \u79cd\u80bd\u5177\u6709\u6d3b\u6027\uff0c\u5176\u4e2d 63 \u79cd\u9488\u5bf9\u75c5\u539f\u4f53\u3002\u8fd9\u4e9b\u6d3b\u6027 AMP \u901a\u8fc7\u7834\u574f\u7ec6\u83cc\u819c\u8868\u73b0\u51fa\u6297\u83cc\u6d3b\u6027\u3002\u603b\u4e4b\uff0c\u8fd9\u79cd\u65b9\u6cd5\u786e\u5b9a\u4e86\u8fd1\u4e00\u767e\u4e07\u4e2a\u539f\u6838 AMP \u5e8f\u5217\uff0c\u8fd9\u662f\u4e00\u79cd\u6297\u751f\u7d20\u53d1\u73b0\u7684\u5f00\u653e\u8d44\u6e90\u3002<\/p>\n

\u6297\u751f\u7d20\u80bd\u53bb\u706d\u7edd<\/strong><\/p>\n

<\/a><\/p>\n

\u56fe\u793a\uff1a\u5229\u7528\u6df1\u5ea6\u5b66\u4e60<\/mark>\u4ece\u53e4\u4ee3\u86cb\u767d\u8d28\u7ec4\u4e2d\u5206\u5b50\u53bb\u9664\u6297\u751f\u7d20\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/section>\n

\u5728\u300aNature Biomedical Engineering<\/em>\u300b\u7684\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u5c55\u793a\u4e86\u6df1\u5ea6\u5b66\u4e60<\/mark>\u53ef\u7528\u4e8e\u6316\u6398\u6240\u6709\u53ef\u7528\u7684\u706d\u7edd\u751f\u7269\u7684\u86cb\u767d\u8d28\u7ec4\uff0c\u4ee5\u53d1\u73b0\u6297\u751f\u7d20\u80bd\u3002<\/p>\n

De la Fuente \u56e2\u961f\u8bad\u7ec3\u4e86\u7531\u80bd\u5e8f\u5217\u7f16\u7801\u5668\u548c\u795e\u7ecf\u7f51\u7edc<\/mark>\u7ec4\u6210\u7684\u6df1\u5ea6\u5b66\u4e60<\/mark>\u6a21\u578b\u7ec4\u5408\uff0c\u79f0\u4e3a\u6297\u751f\u7d20\u80bd\u53bb\u706d\u7edd\uff08APEX\uff09\uff0c\u7528\u4e8e\u9884\u6d4b\u6297\u83cc\u6d3b\u6027\uff0c\u5e76\u7528\u5b83\u6765\u6316\u6398 10,311,899 \u79cd\u80bd\u3002<\/p>\n

De la Fuente \u5b9e\u9a8c\u5ba4\u7684\u535a\u58eb\u540e\u7814\u7a76\u5458 Marcelo Der Torossian Torres \u8868\u793a\uff0c\u56e2\u961f\u5728\u6784\u5efa APEX \u65f6\uff0c\u9996\u5148\u521b\u5efa\u4e86\u4e00\u4e2a\u300c\u9ad8\u5ea6\u6807\u51c6\u5316\u7684\u6570\u636e\u96c6\u6765\u8bad\u7ec3\u5b83\uff0c\u800c\u8fd9\u5728\u6587\u732e\u4e2d\u662f\u7f3a\u5931\u7684\u2026\u2026\u8fd9\u4ee4\u4eba\u60ca\u8bb6\uff0c\u56e0\u4e3a\u6709\u5982\u6b64\u591a\u7684\u6570\u636e\u96c6\uff0c\u7814\u7a76\u4eba\u5458\u5c06\u4f7f\u7528\u591a\u7ec4\u6570\u636e\u96c6\uff0c\u5047\u8bbe\u6240\u6709\u6837\u672c\u90fd\u662f\u4ee5\u975e\u5e38\u7cfb\u7edf\u3001\u4e00\u81f4\u7684\u65b9\u5f0f\u6536\u96c6\u7684\uff0c\u4f46\u60c5\u51b5\u5e76\u975e\u603b\u662f\u5982\u6b64\u3002\u300d<\/p>\n

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