{"id":34748,"date":"2024-12-12T06:58:02","date_gmt":"2024-12-11T22:58:02","guid":{"rendered":"https:\/\/17aitech.com\/?p=34748"},"modified":"2024-12-12T06:58:02","modified_gmt":"2024-12-11T22:58:02","slug":"%e7%94%9f%e6%88%90394760%e7%a7%8d%e8%9b%8b%e7%99%bd%e8%b4%a8%e8%a1%a8%e5%be%81%ef%bc%8c%e5%93%88%e4%bd%9b%e5%9b%a2%e9%98%9f%e5%bc%80%e5%8f%91ai%e6%a8%a1%e5%9e%8b%ef%bc%8c%e5%85%a8%e9%9d%a2%e7%90%86","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=34748","title":{"rendered":"\u751f\u6210394,760\u79cd\u86cb\u767d\u8d28\u8868\u5f81\uff0c\u54c8\u4f5b\u56e2\u961f\u5f00\u53d1AI\u6a21\u578b\uff0c\u5168\u9762\u7406\u89e3\u86cb\u767d\u8d28\u4e0a\u4e0b\u6587"},"content":{"rendered":"

\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:\u751f\u6210394,760\u79cd\u86cb\u767d\u8d28\u8868\u5f81\uff0c\u54c8\u4f5b\u56e2\u961f\u5f00\u53d1AI\u6a21\u578b\uff0c\u5168\u9762\u7406\u89e3\u86cb\u767d\u8d28\u4e0a\u4e0b\u6587<\/a><\/p>\n

<\/a><\/p>\n

\u7f16\u8f91 | \u841d\u535c\u76ae<\/p>\n

\u4e86\u89e3\u86cb\u767d\u8d28\u529f\u80fd\u548c\u5f00\u53d1\u5206\u5b50\u7597\u6cd5\uff0c\u9700\u8981\u7834\u8bd1\u86cb\u767d\u8d28\u53d1\u6325\u4f5c\u7528\u7684\u7ec6\u80de\u7c7b\u578b\uff0c\u89e3\u6790\u86cb\u767d\u8d28\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u3002<\/p>\n

\u7136\u800c\uff0c\u5bf9\u8de8\u751f\u7269\u80cc\u666f\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u8fdb\u884c\u5efa\u6a21\u5bf9\u4e8e\u73b0\u6709\u7b97\u6cd5\u6765\u8bf4\u4ecd\u7136\u5177\u6709\u6311\u6218\u6027\u3002<\/p>\n

\u5728\u6700\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u54c8\u4f5b\u533b\u5b66\u9662\u7684\u7814\u7a76\u4eba\u5458\u5f00\u53d1\u4e86 PINNACLE\uff0c\u8fd9\u662f\u4e00\u79cd\u751f\u6210\u60c5\u5883\u611f\u77e5<\/mark>\u86cb\u767d\u8d28\u8868\u5f81\u7684\u51e0\u4f55\u6df1\u5ea6\u5b66\u4e60<\/mark>\u65b9\u6cd5\u3002<\/p>\n

PINNACLE \u5229\u7528\u591a\u5668\u5b98\u5355\u7ec6\u80de\u56fe\u8c31\uff0c\u5728\u60c5\u5883\u5316\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u4e0a\u8fdb\u884c\u5b66\u4e60\uff0c\u4ece 24 \u79cd\u7ec4\u7ec7\u7684 156 \u79cd\u7ec6\u80de\u7c7b\u578b\u60c5\u5883\u4e2d\u751f\u6210 394,760 \u79cd\u86cb\u767d\u8d28\u8868\u5f81\u3002<\/p>\n

\u8be5\u7814\u7a76\u4ee5\u300cContextual AI models for single-cell protein biology<\/em>\u300d\u4e3a\u9898\uff0c\u4e8e 2024 \u5e74 7 \u6708 22 \u65e5\u53d1\u5e03\u5728\u300aNature Methods<\/em>\u300b\u3002<\/p>\n

<\/a><\/p>\n

\u86cb\u767d\u8d28\u662f\u7ec6\u80de\u7684\u529f\u80fd\u5355\u4f4d\uff0c\u901a\u8fc7\u76f8\u4e92\u4f5c\u7528\u5b9e\u73b0\u4e0d\u540c\u751f\u7269\u529f\u80fd\u3002\u9ad8\u901a\u91cf\u6280\u672f\u4f7f\u5f97\u7ed8\u5236\u5927\u89c4\u6a21\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u56fe\u6210\u4e3a\u53ef\u80fd\uff0c\u5e76\u901a\u8fc7\u8ba1\u7b97\u65b9\u6cd5\u6539\u8fdb\u5bf9\u86cb\u767d\u8d28\u7ed3\u6784\u7684\u7406\u89e3\u3001\u529f\u80fd\u6ce8\u91ca\u7684\u9884\u6d4b\u548c\u6cbb\u7597\u9776\u70b9\u7684\u8bbe\u8ba1\u3002\u8868\u793a\u5b66\u4e60\u65b9\u6cd5\u901a\u8fc7\u6574\u5408\u5206\u5b50\u7ec6\u80de\u56fe\u8c31\uff0c\u80fd\u591f\u89e3\u6790\u4e0d\u540c\u7ec4\u7ec7\u548c\u7ec6\u80de\u7c7b\u578b\u7684\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\uff0c\u6269\u5c55\u5bf9\u86cb\u767d\u8d28\u4e0e\u529f\u80fd\u5173\u7cfb\u7684\u7406\u89e3\u3002<\/p>\n

\u7136\u800c\uff0c\u86cb\u767d\u8d28\u5728\u4e0d\u540c\u751f\u7269\u80cc\u666f\u4e2d\u5177\u6709\u4e0d\u540c\u7684\u4f5c\u7528\uff0c\u57fa\u56e0\u8868\u8fbe\u548c\u86cb\u767d\u8d28\u529f\u80fd\u56e0\u5065\u5eb7\u4e0e\u75be\u75c5\u72b6\u6001\u4e0d\u540c\u800c\u5f02\u3002\u73b0\u6709\u6df1\u5ea6\u5b66\u4e60<\/mark>\u65b9\u6cd5\u751f\u6210\u7684\u86cb\u767d\u8d28\u8868\u793a\u662f\u65e0\u80cc\u666f\u7684\uff0c\u65e0\u6cd5\u8bc6\u522b\u5728\u4e0d\u540c\u7ec6\u80de\u7c7b\u578b\u4e2d\u7684\u529f\u80fd\u53d8\u5316\uff0c\u4ece\u800c\u5f71\u54cd\u591a\u6548\u6027\u548c\u7279\u5f02\u6027\u9884\u6d4b\u3002<\/p>\n

\u6d4b\u91cf\u5355\u7ec6\u80de\u5206\u8fa8\u7387\u57fa\u56e0\u8868\u8fbe\u7684\u6d4b\u5e8f\u6280\u672f\u4e3a\u89e3\u51b3\u8fd9\u4e00\u6311\u6218\u94fa\u5e73\u4e86\u9053\u8def\u3002\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u56fe\u8c31\u6d4b\u91cf\u8bb8\u591a\u7ec6\u80de\u80cc\u666f\u4e0b\u7684\u6d3b\u5316\u57fa\u56e0\u3002\u901a\u8fc7\u57fa\u4e8e\u6ce8\u610f\u529b\u7684\u6df1\u5ea6\u5b66\u4e60<\/mark>\uff0c\u8be5\u65b9\u6cd5\u53ef\u4ee5\u5173\u6ce8\u5927\u578b\u8f93\u5165\u5e76\u5b66\u4e60\u5728\u6bcf\u4e2a\u80cc\u666f\u4e2d\u6700\u91cd\u8981\u7684\u5143\u7d20\uff0c\u5355\u7ec6\u80de\u56fe\u8c31\u53ef\u4ee5\u7528\u4e8e\u589e\u5f3a\u9a71\u52a8\u75be\u75c5\u8fdb\u5c55\u7684\u57fa\u56e0\u8c03\u63a7\u7f51\u7edc\u7684\u7ed8\u5236\uff0c\u5e76\u63ed\u793a\u6cbb\u7597\u9776\u70b9\u3002<\/p>\n

\u7136\u800c\uff0c\u5c06\u86cb\u767d\u8d28\u7f16\u7801\u57fa\u56e0\u7684\u8868\u8fbe\u6574\u5408\u5230\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u4e2d\u4ecd\u662f\u4e00\u4e2a\u6311\u6218\u3002\u73b0\u6709\u7b97\u6cd5\uff0c\u5305\u62ec\u86cb\u767d\u8d28\u8868\u793a\u5b66\u4e60\uff0c\u65e0\u6cd5\u5c06\u86cb\u767d\u8d28\u8868\u793a\u4e0e\u5177\u4f53\u80cc\u666f\u76f8\u8054\u7cfb\u3002<\/p>\n

\u54c8\u4f5b\u533b\u5b66\u9662\u7684\u7814\u7a76\u4eba\u5458\u5f15\u5165\u4e86 PINNACLE\uff08\u57fa\u4e8e\u86cb\u767d\u8d28\u7f51\u7edc\u7684\u4e0a\u4e0b\u6587\u5b66\u4e60\u7b97\u6cd5\uff09\uff0c\u8fd9\u662f\u4e00\u79cd\u7528\u4e8e\u5168\u9762\u7406\u89e3\u86cb\u767d\u8d28\u7684\u4e0a\u4e0b\u6587\u7279\u5b9a\u6a21\u578b\u3002PINNACLE \u662f\u4e00\u79cd\u51e0\u4f55\u6df1\u5ea6\u5b66\u4e60<\/mark>\u6a21\u578b\uff0c\u64c5\u957f\u901a\u8fc7\u5206\u6790\u5404\u79cd\u7ec6\u80de\u73af\u5883\u4e2d\u7684\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u6765\u751f\u6210\u86cb\u767d\u8d28\u8868\u5f81\u3002<\/p>\n

<\/a><\/p>\n

\u56fe\u793a\uff1aPINNACLE \u6982\u89c8\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/section>\n

PINNACLE \u5728\u4e00\u7ec4\u96c6\u6210\u7684\u60c5\u5883\u611f\u77e5<\/mark>\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\uff08PPI\uff09\u4e0a\u8fdb\u884c\u8bad\u7ec3\uff0c\u5e76\u8f85\u4ee5\u6355\u6349\u7ec6\u80de\u76f8\u4e92\u4f5c\u7528\u548c\u7ec4\u7ec7\u5c42\u6b21\u7684\u7f51\u7edc\uff0c\u4ece\u800c\u751f\u6210\u60c5\u5883\u5316\u7684\u86cb\u767d\u8d28\u8868\u5f81\uff0c\u8fd9\u4e9b\u8868\u5f81\u9488\u5bf9\u86cb\u767d\u8d28\u7f16\u7801\u57fa\u56e0\u88ab\u6fc0\u6d3b\u7684\u7ec6\u80de\u7c7b\u578b\u8fdb\u884c\u5b9a\u5236\u3002<\/p>\n

\u4e0e\u4e0a\u4e0b\u6587\u65e0\u5173\u7684\u6a21\u578b\u4e0d\u540c\uff0cPINNACLE \u4e3a\u6bcf\u79cd\u86cb\u767d\u8d28\u751f\u6210\u591a\u79cd\u8868\u793a\uff0c\u6bcf\u79cd\u8868\u793a\u53d6\u51b3\u4e8e\u5176\u7279\u5b9a\u7684\u7ec6\u80de\u7c7b\u578b\u4e0a\u4e0b\u6587\u3002\u6b64\u5916\uff0cPINNACLE \u8fd8\u751f\u6210\u7ec6\u80de\u7c7b\u578b\u4e0a\u4e0b\u6587\u7684\u8868\u793a\u548c\u7ec4\u7ec7\u5c42\u6b21\u7684\u8868\u793a\u3002\u8fd9\u79cd\u65b9\u6cd5\u786e\u4fdd\u4e86\u5bf9\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u7684\u591a\u65b9\u9762\u7406\u89e3\uff0c\u540c\u65f6\u8003\u8651\u5230\u86cb\u767d\u8d28\u4f5c\u7528\u7684\u65e0\u6570\u80cc\u666f\u3002<\/p>\n

\u7ed9\u5b9a\u591a\u5c3a\u5ea6\u6a21\u578b\u8f93\u5165\uff0cPINNACLE \u901a\u8fc7\u4f18\u5316\u7edf\u4e00\u7684\u6f5c\u5728\u8868\u793a\u7a7a\u95f4\u6765\u5b66\u4e60\u86cb\u767d\u8d28\u3001\u7ec6\u80de\u7c7b\u578b\u548c\u7ec4\u7ec7\u7684\u62d3\u6251\u7ed3\u6784\u3002PINNACLE \u5c06\u4e0d\u540c\u7684\u4e0a\u4e0b\u6587\u7279\u5b9a\u6570\u636e\u96c6\u6210<\/mark>\u5230\u4e00\u4e2a\u4e0a\u4e0b\u6587\u611f\u77e5<\/mark>\u6a21\u578b\u4e2d\uff0c\u5e76\u5728\u86cb\u767d\u8d28\u3001\u7ec6\u80de\u7c7b\u578b\u548c\u7ec4\u7ec7\u7ea7\u6570\u636e\u4e4b\u95f4\u4f20\u9012\u77e5\u8bc6\uff0c\u4ee5\u4f7f\u8868\u793a\u5177\u6709\u4e0a\u4e0b\u6587\u76f8\u5173\u6027\u3002<\/p>\n

\u4e3a\u4e86\u5c06\u7ec6\u80de\u548c\u7ec4\u7ec7\u7ec4\u7ec7\u6ce8\u5165\u8fd9\u4e2a\u5d4c\u5165\u7a7a\u95f4\uff0cPINNACLE \u91c7\u7528\u86cb\u767d\u8d28\u3001\u7ec6\u80de\u7c7b\u578b\u548c\u7ec4\u7ec7\u6c34\u5e73\u7684\u6ce8\u610f\u529b\u4ee5\u53ca\u5404\u81ea\u7684\u76ee\u6807\u51fd\u6570<\/mark>\u3002<\/p>\n

\u4ece\u6982\u5ff5\u4e0a\u8bb2\uff0c\u7269\u7406\u4e0a\u76f8\u4e92\u4f5c\u7528\u7684\u86cb\u767d\u8d28\u5bf9\uff08\u5373\u901a\u8fc7\u8f93\u5165\u7f51\u7edc\u4e2d\u7684\u8fb9\u7f18\u8fde\u63a5\uff09\u662f\u7d27\u5bc6\u5d4c\u5165\u7684\u3002\u7c7b\u4f3c\u5730\uff0c\u86cb\u767d\u8d28\u5d4c\u5165\u5728\u5b83\u4eec\u5404\u81ea\u7684\u7ec6\u80de\u7c7b\u578b\u73af\u5883\u9644\u8fd1\uff0c\u540c\u65f6\u4e0e\u4e0d\u76f8\u5173\u7684\u7ec6\u80de\u7c7b\u578b\u4fdd\u6301\u76f8\u5f53\u5927\u7684\u8ddd\u79bb\u3002<\/p>\n

\u8fd9\u786e\u4fdd\u4e86\u76f8\u540c\u7ec6\u80de\u7c7b\u578b\u73af\u5883\u4e2d\u7684\u76f8\u4e92\u4f5c\u7528\u86cb\u767d\u8d28\u4f4d\u4e8e\u5d4c\u5165\u7a7a\u95f4\u7684\u8fd1\u7aef\uff0c\u4f46\u4e0e\u5176\u4ed6\u7ec6\u80de\u7c7b\u578b\u73af\u5883\u4e2d\u7684\u86cb\u767d\u8d28\u5206\u5f00\u3002\u8fd9\u79cd\u65b9\u6cd5\u4ea7\u751f\u7684\u5d4c\u5165\u7a7a\u95f4\u53ef\u4ee5\u51c6\u786e\u8868\u793a\u86cb\u767d\u8d28\u3001\u7ec6\u80de\u7c7b\u578b\u548c\u7ec4\u7ec7\u4e4b\u95f4\u9519\u7efc\u590d\u6742\u7684\u5173\u7cfb\u3002<\/p>\n

PINNACLE \u4f7f\u7528\u4e00\u7cfb\u5217\u9488\u5bf9\u6bcf\u4e2a\u7279\u5b9a\u8282\u70b9\u548c\u8fb9\u7f18\u7c7b\u578b\u91cf\u8eab\u5b9a\u5236\u7684\u6ce8\u610f\u529b\u673a\u5236<\/mark>\u5728\u86cb\u767d\u8d28\u3001\u7ec6\u80de\u7c7b\u578b\u548c\u7ec4\u7ec7\u4e4b\u95f4\u4f20\u64ad\u56fe\u795e\u7ecf\u7f51\u7edc<\/mark>\u4fe1\u606f\u3002<\/p>\n

<\/a><\/p>\n

\u56fe\u793a\uff1aPINNACLE \u86cb\u767d\u8d28\u5d4c\u5165\u533a\u57df\u7684\u5bcc\u96c6\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/section>\n

\u86cb\u767d\u8d28\u7ea7\u9884\u8bad\u7ec3\u4efb\u52a1\u8003\u8651\u5bf9\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u8fdb\u884c\u81ea\u76d1\u7763\u94fe\u63a5\u9884\u6d4b\u548c\u5bf9\u86cb\u767d\u8d28\u8282\u70b9\u8fdb\u884c\u7ec6\u80de\u7c7b\u578b\u5206\u7c7b\u3002\u8fd9\u4e9b\u4efb\u52a1\u4f7f PINNACLE \u80fd\u591f\u5851\u9020\u4e00\u4e2a\u5d4c\u5165\u7a7a\u95f4\uff0c\u8be5\u7a7a\u95f4\u5c01\u88c5\u4e86\u4e0a\u4e0b\u6587\u611f\u77e5<\/mark>\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u7684\u62d3\u6251\u7ed3\u6784\u548c\u86cb\u767d\u8d28\u7684\u7ec6\u80de\u7c7b\u578b\u8eab\u4efd\u3002<\/p>\n

PINNACLE \u7684\u7ec6\u80de\u7c7b\u578b\u548c\u7ec4\u7ec7\u7279\u5b9a\u9884\u8bad\u7ec3\u4efb\u52a1\u5b8c\u5168\u4f9d\u8d56\u4e8e\u81ea\u76d1\u7763\u94fe\u63a5\u9884\u6d4b\uff0c\u4ece\u800c\u4fc3\u8fdb\u7ec6\u80de\u548c\u7ec4\u7ec7\u7ec4\u7ec7\u7684\u5b66\u4e60\u3002\u7ec6\u80de\u7c7b\u578b\u548c\u7ec4\u7ec7\u7684\u62d3\u6251\u7ed3\u6784\u901a\u8fc7\u6ce8\u610f\u529b\u6865\u63a5\u673a\u5236\u4f20\u9012\u7ed9\u86cb\u767d\u8d28\u8868\u793a\uff0c\u6709\u6548\u5730\u5c06\u7ec4\u7ec7\u548c\u7ec6\u80de\u7ec4\u7ec7\u5f3a\u5316\u5230\u86cb\u767d\u8d28\u8868\u793a\u4e0a\u3002<\/p>\n

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\u8bba\u6587\u94fe\u63a5\uff1ahttps:\/\/www.nature.com\/articles\/s41592-024-02341-3<\/em><\/p>\n

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