{"id":35373,"date":"2024-12-24T03:59:50","date_gmt":"2024-12-23T19:59:50","guid":{"rendered":"https:\/\/17aitech.com\/?p=35373"},"modified":"2024-12-24T03:59:50","modified_gmt":"2024-12-23T19:59:50","slug":"%e7%ba%b3%e7%b1%b3%e7%ba%a7%e7%b2%be%e5%ba%a6%ef%bc%8c%e7%97%85%e6%af%92%e6%84%9f%e6%9f%931h%e5%86%85%e5%8d%b3%e5%8f%af%e6%a3%80%e6%b5%8b%e5%88%b0%ef%bc%8c%e5%8d%97%e6%96%b9%e5%8c%bb%e7%a7%91%e5%a4%a7","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=35373","title":{"rendered":"\u7eb3\u7c73\u7ea7\u7cbe\u5ea6\uff0c\u75c5\u6bd2\u611f\u67d31h\u5185\u5373\u53ef\u68c0\u6d4b\u5230\uff0c\u5357\u65b9\u533b\u79d1\u5927\u5b66\u7ec6\u80de\u6838AI\u5de5\u5177\u767bNature\u5b50\u520a"},"content":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2024-09-02-2\" target=\"_blank\">\u7eb3\u7c73\u7ea7\u7cbe\u5ea6\uff0c\u75c5\u6bd2\u611f\u67d31h\u5185\u5373\u53ef\u68c0\u6d4b\u5230\uff0c\u5357\u65b9\u533b\u79d1\u5927\u5b66\u7ec6\u80de\u6838AI\u5de5\u5177\u767bNature\u5b50\u520a<\/a><\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/09\/frc-c650b2e53fdc479469d5daa16c6d2087.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/09\/frc-c650b2e53fdc479469d5daa16c6d2087.png\"><\/a><\/section>\n<p>\u7f16\u8f91 |\u00a0KX<\/p>\n<p>\u4e00\u7eb3\u7c73 (nm) \u662f\u4e00\u7c73\u7684\u5341\u4ebf\u5206\u4e4b\u4e00\uff0c\u800c\u4eba\u7c7b\u4e00\u6839\u5934\u53d1\u7684\u5bbd\u5ea6\u7ea6\u4e3a 100,000 nm\u3002<\/p>\n<p>\u5982\u4eca\uff0c<mark data-type=\"concepts\" data-id=\"2d28aa9c-942d-471d-bd96-8bfefb7144e0\">\u4eba\u5de5\u667a\u80fd<\/mark>\u53ef\u4ee5\u68c0\u6d4b\u5230\u7ec6\u80de\u5185\u5c0f\u81f3 20 nm \u7684\u91cd\u6392\uff0c\u5373\u6bd4\u4eba\u7c7b\u5934\u53d1\u5bbd\u5ea6\u5c0f 5,000 \u500d\u3002\u800c\u8fd9\u4e9b\u6539\u53d8\u592a\u5c0f\u592a\u5fae\u5999\uff0c\u9760\u4eba\u7c7b\u4ec5\u7528\u4f20\u7edf\u65b9\u6cd5\u662f\u65e0\u6cd5\u53d1\u73b0\u7684\u3002<\/p>\n<p>\u8fd1\u65e5\uff0c\u5357\u65b9\u533b\u79d1\u5927\u5b66\u548c\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3\u79d1\u5b66\u6280\u672f\u7814\u7a76\u6240\u7684\u7814\u7a76\u56e2\u961f\uff0c\u5f00\u53d1\u4e86\u4e00\u79cd\u7ec6\u80de\u6838<mark data-type=\"concepts\" data-id=\"2d28aa9c-942d-471d-bd96-8bfefb7144e0\">\u4eba\u5de5\u667a\u80fd<\/mark>\uff08AINU\uff09\u5de5\u5177\uff0c\u53ef\u4ee5\u5728\u7eb3\u7c73\u7ea7\u5206\u8fa8\u7387\u4e0b\u8bc6\u522b\u7279\u5b9a\u7684\u7ec6\u80de\u6838\u7279\u5f81\u3002\u5b83\u53ef\u4ee5\u533a\u5206\u764c\u7ec6\u80de\u548c\u6b63\u5e38\u7ec6\u80de\uff0c\u5e76\u68c0\u6d4b\u51fa\u7ec6\u80de\u5185\u75c5\u6bd2\u611f\u67d3\u7684\u65e9\u671f\u9636\u6bb5\u3002<\/p>\n<p>\u8bba\u6587\u5171\u540c\u4e00\u4f5c\u3001\u5357\u65b9\u533b\u79d1\u5927\u5b66\u5e7f\u4e1c\u7701\u4eba\u6c11\u533b\u9662 (GDPH) \u7814\u7a76\u5458 Limei Zhong \u8bf4\u9053\uff1a\u300c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u5229\u7528\u8fd9\u9879\u6280\u672f\u89c2\u5bdf\u75c5\u6bd2\u8fdb\u5165\u4eba\u4f53\u540e\u5982\u4f55\u7acb\u5373\u5f71\u54cd\u7ec6\u80de\uff0c\u8fd9\u6709\u52a9\u4e8e\u5f00\u53d1\u66f4\u597d\u7684\u6cbb\u7597\u65b9\u6cd5\u548c\u75ab\u82d7\u3002\u5728\u533b\u9662\u548c\u8bca\u6240\uff0cAINU \u53ef\u7528\u4e8e\u4ece\u7b80\u5355\u7684\u8840\u6db2\u6216\u7ec4\u7ec7\u6837\u672c\u5feb\u901f\u8bca\u65ad\u611f\u67d3\uff0c\u4f7f\u8bca\u65ad\u8fc7\u7a0b\u66f4\u5feb\u3001\u66f4\u51c6\u786e\u3002\u300d<\/p>\n<p>\u76f8\u5173\u7814\u7a76\u4ee5\u300c<em>A deep learning method that identifies cellular heterogeneity using nanoscale nuclear features<\/em>\u300d\u4e3a\u9898\uff0c\u53d1\u8868\u5728\u300a<em>Nature Machine Intelligence<\/em>\u300b\u4e0a\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/09\/frc-529a007fd3cb59d3f2be899d03424f0f.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/09\/frc-529a007fd3cb59d3f2be899d03424f0f.png\"><\/a><\/p>\n<section>\u8bba\u6587\u94fe\u63a5\uff1a<em>https:\/\/www.nature.com\/articles\/s42256-024-00883-x<\/em><\/section>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_78 ez-toc-wrap-left-text counter-hierarchy ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u6587\u7ae0\u76ee\u5f55<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/17aitech.com\/?p=35373\/#%E7%BA%B3%E7%B1%B3%E7%BA%A7%E5%88%86%E8%BE%A8%E7%8E%87%E6%98%BE%E5%BE%AE%E9%95%9C\" >\u7eb3\u7c73\u7ea7\u5206\u8fa8\u7387\u663e\u5fae\u955c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/17aitech.com\/?p=35373\/#%E5%88%86%E5%AD%90%E6%B0%B4%E5%B9%B3%E7%9A%84%E3%80%8C%E9%9D%A2%E9%83%A8%E8%AF%86%E5%88%AB%E3%80%8D\" >\u5206\u5b50\u6c34\u5e73\u7684\u300c\u9762\u90e8\u8bc6\u522b\u300d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/17aitech.com\/?p=35373\/#%E4%B8%BA%E4%B8%B4%E5%BA%8A%E5%87%86%E5%A4%87%E5%A5%A0%E5%AE%9A%E5%9F%BA%E7%A1%80\" >\u4e3a\u4e34\u5e8a\u51c6\u5907\u5960\u5b9a\u57fa\u7840<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E7%BA%B3%E7%B1%B3%E7%BA%A7%E5%88%86%E8%BE%A8%E7%8E%87%E6%98%BE%E5%BE%AE%E9%95%9C\"><\/span><strong>\u7eb3\u7c73\u7ea7\u5206\u8fa8\u7387\u663e\u5fae\u955c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>\u7ec6\u80de\u8868\u578b\u5f02\u8d28\u6027\u662f\u8bb8\u591a\u751f\u7269\u529f\u80fd\u7684\u5173\u952e\u51b3\u5b9a\u56e0\u7d20\uff0c\u4e86\u89e3\u5176\u8d77\u6e90\u4ecd\u7136\u662f\u4e00\u9879\u8270\u5de8\u7684\u6311\u6218\u3002\u8fd9\u79cd\u5f02\u8d28\u6027\u901a\u5e38\u53cd\u6620\u4e86\u67d3\u8272\u8d28\u7ed3\u6784\u7684\u53d8\u5316\uff0c\u53d7\u75c5\u6bd2\u611f\u67d3\u548c\u764c\u75c7\u7b49\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u8fd9\u4e9b\u56e0\u7d20\u6781\u5927\u5730\u91cd\u5851\u4e86\u7ec6\u80de\u666f\u89c2\u3002<\/p>\n<p>\u5355\u5206\u5b50\u5b9a\u4f4d\u663e\u5fae\u955c (SMLM) \uff0c\u7279\u522b\u662f\u968f\u673a\u5149\u5b66\u91cd\u5efa\u663e\u5fae\u955c (STORM)\uff0c\u53ef\u4ee5\u786e\u5b9a\u7ec6\u80de\u4e2d\u67d3\u8272\u8d28\u7ea4\u7ef4\u7684\u7eb3\u7c73\u7ea7\u6392\u5217\u3002\u5f53\u524d\u5206\u6790\u5355\u5206\u5b50\u7a7a\u95f4\u5206\u5e03\u7684\u65b9\u6cd5\uff08\u4f8b\u5982<mark data-type=\"concepts\" data-id=\"de069734-8912-43fb-b365-3b014165bc4d\">\u805a\u7c7b<\/mark>\u7b97\u6cd5\uff09\u5728\u63d0\u53d6\u6838\u4f4d\u7f6e\u53ca\u5176\u5c40\u90e8\u5bc6\u5ea6\u65b9\u9762\u975e\u5e38\u6709\u6548\u3002\u7136\u800c\uff0c\u76ee\u524d\u5c1a\u4e0d\u6e05\u695a\u5982\u4f55\u5229\u7528\u8fd9\u4e9b\u5206\u5b50\u7684\u7a7a\u95f4\u5206\u5e03\u548c\u5bc6\u5ea6\u6765\u8bc6\u522b\u7ec6\u80de\u72b6\u6001\u3002<\/p>\n<p><mark data-type=\"tech_methods\" data-id=\"85c4b79b-6428-4184-b9bc-5beb6e2b1f3f\">\u5377\u79ef\u795e\u7ecf\u7f51\u7edc<\/mark> (CNN) \u5df2\u5e7f\u6cdb\u7528\u4e8e\u5404\u79cd\u533b\u7597\u4fdd\u5065\u6210\u50cf\u9886\u57df\u3002<mark data-type=\"tech_methods\" data-id=\"01946acc-d031-4c0e-909c-f062643b7273\">\u6df1\u5ea6\u5b66\u4e60<\/mark> (DL) \u6a21\u578b\u5df2\u7528\u4e8e\u5bf9\u5168\u7ec6\u80de\u56fe\u50cf\u8fdb\u884c\u5206\u7c7b\u5e76\u4f7f\u7528\u884d\u5c04\u6781\u9650\u663e\u5fae\u955c\u8fdb\u884c\u8ddf\u8e2a\u3002\u6b64\u5916\uff0c\u8d85\u5206\u8fa8\u7387 (SR) \u663e\u5fae\u955c\u8fd8\u7528\u4e8e\u63d0\u9ad8\u6570\u636e\u91c7\u96c6\u8fc7\u7a0b\u4e2d\u7684\u5b9a\u4f4d\u7cbe\u5ea6\u548c<mark data-type=\"tech_tasks\" data-id=\"ce9b1ebe-295c-4e80-aa0e-22956b5f635c\">\u8bed\u4e49\u5206\u5272<\/mark>\uff0c\u4f46\u76ee\u524d\u5c1a\u672a\u4f7f\u7528 SMLM \u56fe\u50cf\u6839\u636e\u4e9a\u7ec6\u80de\u7ed3\u6784\u5bf9\u7ec6\u80de\u8fdb\u884c\u5206\u7c7b\u3002<\/p>\n<h1><span class=\"ez-toc-section\" id=\"%E5%88%86%E5%AD%90%E6%B0%B4%E5%B9%B3%E7%9A%84%E3%80%8C%E9%9D%A2%E9%83%A8%E8%AF%86%E5%88%AB%E3%80%8D\"><\/span><strong>\u5206\u5b50\u6c34\u5e73\u7684\u300c\u9762\u90e8\u8bc6\u522b\u300d<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>\u7528\u8138\u89e3\u9501\u667a\u80fd\u624b\u673a\uff0c\u6216<mark data-type=\"apply_tasks\" data-id=\"3c71466b-dbc1-409a-81d4-05bc6df49ab8\">\u81ea\u52a8\u9a7e\u9a76\u6c7d\u8f66<\/mark>\u901a\u8fc7\u8bc6\u522b\u9053\u8def\u4e0a\u7684\u7269\u4f53\u6765\u7406\u89e3\u548c\u5bfc\u822a\u73af\u5883\u7b49\uff0c\u90fd\u5229\u7528\u4e86<mark data-type=\"tech_methods\" data-id=\"85c4b79b-6428-4184-b9bc-5beb6e2b1f3f\">\u5377\u79ef\u795e\u7ecf\u7f51\u7edc<\/mark>\u3002<\/p>\n<p>\u5728\u533b\u5b66\u9886\u57df\uff0c<mark data-type=\"tech_methods\" data-id=\"85c4b79b-6428-4184-b9bc-5beb6e2b1f3f\">\u5377\u79ef\u795e\u7ecf\u7f51\u7edc<\/mark>\u88ab\u7528\u6765\u5206\u6790\u533b\u5b66\u56fe\u50cf\uff0c\u5982\u4e73\u623f X \u5149\u7247\u6216 CT \u626b\u63cf\u7b49\uff0c\u5e76\u8bc6\u522b\u4eba\u773c\u53ef\u80fd\u9057\u6f0f\u7684\u764c\u75c7\u8ff9\u8c61\u3002\u5b83\u4eec\u8fd8\u53ef\u4ee5\u5e2e\u52a9\u533b\u751f\u68c0\u6d4b MRI \u626b\u63cf\u6216 X \u5c04\u7ebf\u56fe\u50cf\u4e2d\u7684\u5f02\u5e38\uff0c\u4ece\u800c\u5e2e\u52a9\u533b\u751f\u66f4\u5feb\u3001\u66f4\u51c6\u786e\u5730\u505a\u51fa\u8bca\u65ad\u3002<\/p>\n<p>AINU \u662f\u4e00\u79cd<mark data-type=\"tech_methods\" data-id=\"85c4b79b-6428-4184-b9bc-5beb6e2b1f3f\">\u5377\u79ef\u795e\u7ecf\u7f51\u7edc<\/mark>\uff0c\u662f\u4e00\u79cd\u4e13\u95e8\u7528\u4e8e\u5206\u6790\u56fe\u50cf\u7b49\u89c6\u89c9\u6570\u636e\u7684 AI\u3002\u53ef\u4ee5\u4f7f\u7528\u6765\u81ea\u6838\u7279\u5f81\u6210\u50cf\u7684\u6700\u5c11\u8bad\u7ec3\u6570\u636e\u6709\u6548\u5730\u8bad\u7ec3 CNN \u67b6\u6784\u3002<\/p>\n<p>AINU \u53ef\u626b\u63cf\u9ad8\u5206\u8fa8\u7387\u7ec6\u80de\u56fe\u50cf\uff0c\u8fd9\u4e9b\u56fe\u50cf\u662f\u901a\u8fc7 STORM \u83b7\u5f97\u7684\uff0c\u8be5\u6280\u672f\u53ef\u4ee5\u6355\u6349\u5230\u6bd4\u666e\u901a\u663e\u5fae\u955c\u66f4\u7cbe\u7ec6\u7684\u7ec6\u8282\u3002\u9ad8\u6e05\u5feb\u7167\u53ef\u4ee5\u663e\u793a\u7eb3\u7c73\u7ea7\u5206\u8fa8\u7387\u7684\u7ed3\u6784\u3002<\/p>\n<p>\u300c\u8fd9\u4e9b\u56fe\u50cf\u7684\u5206\u8fa8\u7387\uff0c\u8db3\u4ee5\u8ba9\u6211\u4eec\u7684 AI \u4ee5\u60ca\u4eba\u7684\u51c6\u786e\u5ea6\u8bc6\u522b\u7279\u5b9a\u7684\u6a21\u5f0f\u548c\u5dee\u5f02\uff0c\u5305\u62ec\u7ec6\u80de\u5185 DNA \u6392\u5217\u65b9\u5f0f\u7684\u53d8\u5316\uff0c\u4ece\u800c\u53ef\u4ee5\u5e2e\u52a9\u6211\u4eec\u5f88\u5feb\u53d1\u73b0\u5176\u53d8\u5316\u3002\u6211\u8ba4\u4e3a\uff0c\u6709\u4e00\u5929\uff0c\u8fd9\u7c7b\u4fe1\u606f\u53ef\u4ee5\u4e3a\u533b\u751f\u8d62\u5f97\u5b9d\u8d35\u7684\u65f6\u95f4\u6765\u76d1\u6d4b\u75be\u75c5\u3001\u4e2a\u6027\u5316\u6cbb\u7597\u548c\u6539\u5584\u60a3\u8005\u9884\u540e\uff0c\u300d\u8be5\u7814\u7a76\u7684\u5171\u540c\u901a\u8baf\u4f5c\u8005\u3001\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3\u79d1\u5b66\u6280\u672f\u7814\u7a76\u6240 Pia Cosma \u6559\u6388\u8bf4\u9053\u3002<\/p>\n<p>\u4e3a\u4e86\u9009\u62e9\u7528\u4e8e\u8bc6\u522b\u4f53\u7ec6\u80de\u548c\u4eba\u7c7b\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08hiPSC\uff09\u7684\u6700\u4f73 CNN \u67b6\u6784\u53ca\u5176<mark data-type=\"concepts\" data-id=\"5619ca3f-5d4e-48c1-824d-d2a0aea0c7d1\">\u8d85\u53c2\u6570<\/mark>\uff0c\u7814\u7a76\u4eba\u5458\u6bd4\u8f83\u4e86 11 \u79cd\u4e0d\u540c\u7684 CNN \u67b6\u6784\uff0c\u6700\u7ec8\uff0cDenseNet-121 \u5728\u8bc6\u522b\u4f53\u7ec6\u80de\u548c hiPSC \u65b9\u9762\u8868\u73b0\u6700\u4f73\uff0c\u5e73\u5747\u9a8c\u8bc1<mark data-type=\"concepts\" data-id=\"8be77eae-12da-4e9e-9a88-b7f5bae98c2e\">\u51c6\u786e\u7387<\/mark>\u4e3a 92.26\uff0c\u5e73\u5747\u635f\u5931\u4e3a 0.292\uff0c\u5c06\u5176\u7528\u4e8e\u540e\u7eed\u5206\u6790\u3002<\/p>\n<p>\u9009\u62e9\u57fa\u4e8e\u6a21\u578b\u5728\u603b\u5171 349 \u4e2a\u6838\u53cc\u8272 STORM \u56fe\u50cf\u4e0a\u7684\u6027\u80fd\uff0c\u8fd9\u4e9b\u56fe\u50cf\u662f\u6838\u5c0f\u4f53\u6838\u5fc3\u7ec4\u86cb\u767d H3 \u548c Pol II\u3002\u6240\u9009\u5206\u5b50\u7684\u8367\u5149\u56e2\u662f\u4ece\u4e0d\u540c\u4f53\u7ec6\u80de\u7c7b\u578b\u7684\u4eba\u7c7b\u4f53\u7ec6\u80de\u548c hiPSC \u4e2d\u6536\u96c6\u7684\uff0c\u5e76\u6e32\u67d3\u6210\u76f8\u5bf9\u4e8e\u539f\u59cb\u76f8\u673a\u5e27\u653e\u5927 10 \u500d\u7684\u56fe\u50cf\u3002<\/p>\n<p>AINU \u5728\u5206\u5b50\u6c34\u5e73\u4e0a\u68c0\u6d4b\u548c\u5206\u6790\u7ec6\u80de\u5185\u7684\u5fae\u5c0f\u7ed3\u6784\u3002\u7814\u7a76\u4eba\u5458\u901a\u8fc7\u5411\u6a21\u578b\u8f93\u5165\u4e0d\u540c\u72b6\u6001\u4e0b\u4e0d\u540c\u7c7b\u578b\u7ec6\u80de\u7684\u7ec6\u80de\u6838\u7684\u7eb3\u7c73\u7ea7\u5206\u8fa8\u7387\u56fe\u50cf\u6765\u8bad\u7ec3\u6a21\u578b\u3002\u8be5\u6a21\u578b\u901a\u8fc7\u5206\u6790\u7ec6\u80de\u6838\u6210\u5206\u5728\u4e09\u7ef4\u7a7a\u95f4\u4e2d\u7684\u5206\u5e03\u548c\u6392\u5217\u65b9\u5f0f\uff0c\u5b66\u4f1a\u4e86\u8bc6\u522b\u7ec6\u80de\u4e2d\u7684\u7279\u5b9a\u6a21\u5f0f\u3002<\/p>\n<p>\u4f8b\u5982\uff0c\u4e0e\u6b63\u5e38\u7ec6\u80de\u76f8\u6bd4\uff0c\u764c\u7ec6\u80de\u7684\u7ec6\u80de\u6838\u7ed3\u6784\u6709\u660e\u663e\u7684\u53d8\u5316\uff0c\u4f8b\u5982\u5176 DNA \u7684\u7ec4\u7ec7\u65b9\u5f0f\u6216\u7ec6\u80de\u6838\u5185\u9176\u7684\u5206\u5e03\u53d1\u751f\u4e86\u6539\u53d8\u3002\u7ecf\u8fc7\u8bad\u7ec3\u540e\uff0cAINU \u53ef\u4ee5\u5206\u6790\u7ec6\u80de\u6838\u7684\u65b0\u56fe\u50cf\uff0c\u5e76\u4ec5\u6839\u636e\u8fd9\u4e9b\u7279\u5f81\u5c06\u5176\u5f52\u7c7b\u4e3a\u764c\u75c7\u6216\u6b63\u5e38\u7ec6\u80de\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/09\/frc-f2cc167acada66083898c28ff1ad4a7c.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/09\/frc-f2cc167acada66083898c28ff1ad4a7c.png\"><\/a><\/p>\n<section>\u56fe\u793a\uff1a\u4f7f\u7528 Pol II \u548c H3 \u56fe\u50cf\u8bad\u7ec3\u7684 AINU \u53ef\u4ee5\u6b63\u786e\u8bc6\u522b\u4f53\u7ec6\u80de\u548c iPSC\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/section>\n<p>AINU \u53ef\u4ee5\u6839\u636e\u8d85\u5206\u8fa8\u7387\u663e\u5fae\u955c\u56fe\u50cf\u4e2d\u6838\u5fc3\u7ec4\u86cb\u767d H3\u3001RNA \u805a\u5408\u9176 II \u6216 DNA 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\u7d27\u5bc6\u7a0b\u5ea6\u7684\u7ec6\u5fae\u5dee\u5f02\u6765\u68c0\u6d4b\u75c5\u6bd2\u7684\u5b58\u5728\uff0c\u5f53\u75c5\u6bd2\u5f00\u59cb\u6539\u53d8\u7ec6\u80de\u6838\u7ed3\u6784\u65f6\u5c31\u4f1a\u53d1\u751f\u8fd9\u79cd\u60c5\u51b5\u3002<\/p>\n<p>\u300c\u6211\u4eec\u7684\u65b9\u6cd5\u53ef\u4ee5\u5728\u611f\u67d3\u5f00\u59cb\u540e\u5f88\u5feb\u68c0\u6d4b\u5230\u88ab\u75c5\u6bd2\u611f\u67d3\u7684\u7ec6\u80de\u3002\u901a\u5e38\uff0c\u533b\u751f\u9700\u8981\u4e00\u6bb5\u65f6\u95f4\u624d\u80fd\u53d1\u73b0\u611f\u67d3\uff0c\u4ed6\u4eec\u4f9d\u8d56\u4e8e\u53ef\u89c1\u7684\u75c7\u72b6\u6216\u8eab\u4f53\u7684\u8f83\u5927\u53d8\u5316\u3002\u4f46\u4f7f\u7528 AINU\uff0c\u6211\u4eec\u53ef\u4ee5\u7acb\u5373\u770b\u5230\u7ec6\u80de\u6838\u7684\u5fae\u5c0f\u53d8\u5316\uff0c\u300d\u8be5\u7814\u7a76\u7684\u5171\u540c\u901a\u8baf\u4f5c\u8005\u3001\u5df4\u65af\u514b\u5927\u5b66\uff08University of the Basque Country\uff09 Ignacio Arganda-Carreras \u8bf4\u3002<\/p>\n<h1><span class=\"ez-toc-section\" id=\"%E4%B8%BA%E4%B8%B4%E5%BA%8A%E5%87%86%E5%A4%87%E5%A5%A0%E5%AE%9A%E5%9F%BA%E7%A1%80\"><\/span><strong>\u4e3a\u4e34\u5e8a\u51c6\u5907\u5960\u5b9a\u57fa\u7840<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>\u7814\u7a76\u4eba\u5458\u5fc5\u987b\u514b\u670d\u4e00\u4e9b\u91cd\u8981\u7684\u9650\u5236\uff0c\u624d\u80fd\u5728\u4e34\u5e8a\u73af\u5883\u4e2d\u6d4b\u8bd5\u6216\u90e8\u7f72\u8be5\u6280\u672f\u3002\u4f8b\u5982\uff0cSTORM \u56fe\u50cf\u53ea\u80fd\u4f7f\u7528\u5728\u751f\u7269\u533b\u5b66\u7814\u7a76\u5b9e\u9a8c\u5ba4\u4e2d\u7684\u4e13\u7528\u8bbe\u5907\u6765\u62cd\u6444\u3002\u53e6\u4e00\u4e2a\u9650\u5236\u662f STORM \u6210\u50cf\u901a\u5e38\u4e00\u6b21\u53ea\u5206\u6790\u51e0\u4e2a\u7ec6\u80de\u3002<\/p>\n<p>\u300c\u5728 STORM \u6210\u50cf\u9886\u57df\u53d6\u5f97\u8bb8\u591a\u8fdb\u5c55\uff0c\u8fd9\u610f\u5473\u7740\u663e\u5fae\u955c\u53ef\u80fd\u5f88\u5feb\u5c31\u4f1a\u51fa\u73b0\u5728\u8f83\u5c0f\u6216\u4e0d\u592a\u4e13\u4e1a\u7684\u5b9e\u9a8c\u5ba4\u4e2d\uff0c\u6700\u7ec8\u751a\u81f3\u4f1a\u51fa\u73b0\u5728\u8bca\u6240\u4e2d\u3002\u53ef\u8bbf\u95ee\u6027\u548c\u541e\u5410\u91cf\u7684\u9650\u5236\uff0c\u6bd4\u6211\u4eec\u4e4b\u524d\u60f3\u8c61\u7684\u66f4\u5bb9\u6613\u89e3\u51b3\uff0c\u6211\u4eec\u5e0c\u671b\u5f88\u5feb\u5f00\u5c55\u4e34\u5e8a\u524d\u5b9e\u9a8c\uff0c\u300dCosma \u535a\u58eb\u8bf4\u3002<\/p>\n<p>\u5c3d\u7ba1\u4e34\u5e8a\u6548\u76ca\u53ef\u80fd\u8fd8\u9700\u8981\u6570\u5e74\u65f6\u95f4\uff0c\u4f46\u9884\u8ba1 AINU \u5c06\u5728\u77ed\u671f\u5185\u52a0\u901f\u79d1\u5b66\u7814\u7a76\u3002\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c\u8be5\u6280\u672f\u53ef\u4ee5\u975e\u5e38\u7cbe\u786e\u5730\u8bc6\u522b\u5e72\u7ec6\u80de\u3002\u5e72\u7ec6\u80de\u53ef\u4ee5\u53d1\u80b2\u6210\u4f53\u5185\u4efb\u4f55\u7c7b\u578b\u7684\u7ec6\u80de\uff0c\u8fd9\u79cd\u80fd\u529b\u88ab\u79f0\u4e3a\u591a\u80fd\u6027\u3002\u591a\u80fd\u7ec6\u80de\uff08Pluripotent cells\uff09\u5728\u5e2e\u52a9\u4fee\u590d\u6216\u66ff\u6362\u53d7\u635f\u7ec4\u7ec7\u65b9\u9762\u7684\u5177\u6709\u5f88\u5927\u6f5c\u529b\u3002<\/p>\n<p>AINU \u53ef\u4ee5\u4f7f\u68c0\u6d4b\u591a\u80fd\u7ec6\u80de\u7684\u8fc7\u7a0b\u66f4\u5feb\u3001\u66f4\u51c6\u786e\uff0c\u6709\u52a9\u4e8e\u4f7f\u5e72\u7ec6\u80de\u7597\u6cd5\u66f4\u5b89\u5168\u3001\u66f4\u6709\u6548\u3002<\/p>\n<p>\u300c\u76ee\u524d\u68c0\u6d4b\u9ad8\u8d28\u91cf\u5e72\u7ec6\u80de\u7684\u65b9\u6cd5\u4f9d\u8d56\u4e8e\u52a8\u7269\u8bd5\u9a8c\u3002\u7136\u800c\uff0c\u6211\u4eec\u7684 AI \u6a21\u578b\u53ea\u9700\u8981\u4e00\u4e2a\u7528\u7279\u5b9a\u6807\u8bb0\u67d3\u8272\u7684\u6837\u672c\uff0c\u8fd9\u4e9b\u6807\u8bb0\u53ef\u4ee5\u7a81\u51fa\u5173\u952e\u7684\u6838\u7279\u5f81\u3002\u5b83\u4e0d\u4ec5\u66f4\u7b80\u5355\u3001\u66f4\u5feb\u6377\uff0c\u8fd8\u53ef\u4ee5\u52a0\u901f\u5e72\u7ec6\u80de\u7814\u7a76\uff0c\u540c\u65f6\u6709\u52a9\u4e8e\u51cf\u5c11\u52a8\u7269\u5728\u79d1\u5b66\u4e2d\u7684\u4f7f\u7528\u3002\u300d\u8bba\u6587\u4e00\u4f5c\u3001\u5df4\u585e\u7f57\u90a3\u79d1\u5b66\u6280\u672f\u7814\u7a76\u6240\u7814\u7a76\u5458 Davide Carnevali \u8bf4\u3002<\/p>\n<section>\u76f8\u5173\u62a5\u9053\uff1a<em>https:\/\/medicalxpress.com\/news\/2024-08-ai-cancer-viral-infections-nanoscale.html<\/em><\/section>\n<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2024-09-02-2\" target=\"_blank\">\u7eb3\u7c73\u7ea7\u7cbe\u5ea6\uff0c\u75c5\u6bd2\u611f\u67d31h\u5185\u5373\u53ef\u68c0\u6d4b\u5230\uff0c\u5357\u65b9\u533b\u79d1\u5927\u5b66\u7ec6\u80de\u6838AI\u5de5\u5177\u767bNature\u5b50\u520a<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:\u7eb3\u7c73\u7ea7\u7cbe\u5ea6\uff0c\u75c5\u6bd2\u611f\u67d31 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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