{"id":35909,"date":"2025-01-03T00:00:16","date_gmt":"2025-01-02T16:00:16","guid":{"rendered":"https:\/\/17aitech.com\/?p=35909"},"modified":"2025-01-03T00:00:16","modified_gmt":"2025-01-02T16:00:16","slug":"science-%e5%8f%91%e6%96%87%ef%bc%8c%e9%ab%98%e9%80%9a%e9%87%8f%e8%9b%8b%e7%99%bd%e8%b4%a8%e7%bb%84%e5%ad%a6%e5%92%8c%e4%ba%ba%e5%b7%a5%e6%99%ba%e8%83%bd%e7%9a%84%e9%9d%a9%e5%91%bd","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=35909","title":{"rendered":"Science \u53d1\u6587\uff0c\u9ad8\u901a\u91cf\u86cb\u767d\u8d28\u7ec4\u5b66\u548c\u4eba\u5de5\u667a\u80fd\u7684\u9769\u547d"},"content":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2024-10-05-2\" target=\"_blank\">Science \u53d1\u6587\uff0c\u9ad8\u901a\u91cf\u86cb\u767d\u8d28\u7ec4\u5b66\u548c\u4eba\u5de5\u667a\u80fd\u7684\u9769\u547d<\/a><\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-c9476e6a95fbb66959e1b59af8b93760.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-c9476e6a95fbb66959e1b59af8b93760.png\"><\/a><\/section>\n<p>\u7f16\u8bd1 | \u7d2b\u7f57<\/p>\n<p>\u6700\u8fd1\uff0c\u7814\u7a76\u4eba\u5458\u80fd\u591f\u4ece\u5c11\u91cf\u8840\u6db2\u6837\u672c\u4e2d\u6d4b\u91cf\u6570\u5343\u79cd\u8840\u6d46\u86cb\u767d\uff0c\u8fd9\u4e3a\u5e7f\u6cdb\u7684\u6570\u636e\u63d0\u4f9b\u4e86\u65b0\u7684\u7ef4\u5ea6\uff0c\u53ef\u4ee5\u589e\u8fdb\u6211\u4eec\u5bf9\u4eba\u7c7b\u5065\u5eb7\u7684\u4e86\u89e3\u3002<\/p>\n<p>\u4f8b\u5982\uff0cSomaLogic \u516c\u53f8\u5df2\u7ecf\u5f00\u53d1\u51fa\u6d4b\u91cf 10,000 \u591a\u79cd\u86cb\u767d\u8d28\u7684\u65b9\u6cd5\uff0c\u800c\u8d5b\u9ed8\u98de\u4e16\u5c14\u7684 Olink \u68c0\u6d4b\u65b9\u6cd5\u53ef\u4ee5\u4ece\u5c11\u81f3 2 \u03bcl \u7684\u6837\u672c\u4e2d\u68c0\u6d4b 5400 \u591a\u79cd\u86cb\u767d\u8d28\u3002<\/p>\n<p>\u5f53\u8fd9\u4e9b\u4e30\u5bcc\u7684\u6570\u636e\u4e0e\u6765\u81ea\u5927\u578b\u60a3\u8005\u7fa4\u4f53\u7684\u5176\u4ed6\u4fe1\u606f\u5c42\uff08\u4f8b\u5982\u82f1\u56fd\u751f\u7269\u5e93\u4ece 50 \u4e07\u540d\u53c2\u4e0e\u8005\u90a3\u91cc\u83b7\u5f97\u7684\u57fa\u56e0\u3001\u5065\u5eb7\u548c\u751f\u6d3b\u65b9\u5f0f\u4fe1\u606f\uff09\u76f8\u7ed3\u5408\u65f6\uff0c\u6211\u4eec\u5c31\u4f1a\u5bf9\u75be\u75c5\u7684\u6839\u6e90\u3001\u8870\u8001\u8fc7\u7a0b\u4ee5\u53ca\u9884\u6d4b\u4e2a\u4eba\u5065\u5eb7\u8f68\u8ff9\u7684\u6f5c\u5728\u80fd\u529b\u4ea7\u751f\u65b0\u7684\u89c1\u89e3\u3002<\/p>\n<p>\u5341\u591a\u5e74\u6765\uff0c\u79d1\u5b66\u5bb6\u5df2\u7ecf\u5f00\u53d1\u51fa\u9884\u6d4b\u75be\u75c5\u98ce\u9669\u7684\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u5206\uff08polygenic risk scores\uff0cPRS\uff09\u3002PRS \u5df2\u5728\u4e0d\u540c\u8840\u7edf\u7684\u4eba\u7fa4\u4e2d\u5f97\u5230\u9a8c\u8bc1\uff0c\u73b0\u5728\u5f00\u59cb\u7528\u4e8e\u60a3\u8005\u6307\u5bfc\u3002\u8fd9\u4e9b\u98ce\u9669\u8bc4\u5206\u901a\u5e38\u57fa\u4e8e\u6570\u767e\u79cd\u5e38\u89c1\uff08\u5b58\u5728\u4e8e 5% \u4ee5\u4e0a\u7684\u4eba\u53e3\u4e2d\uff09\u5355\u6838\u82f7\u9178\u591a\u6001\u6027\u00a0(SNP) \u7684\u5b58\u5728\u3002<\/p>\n<p>\u4f46\u6211\u4eec\u77e5\u9053\uff0c\u60a3\u75c5\u98ce\u9669\u4e0d\u4ec5\u4ec5\u53cd\u6620\u5728\u5e38\u89c1\u7684 DNA \u5e8f\u5217\u53d8\u5f02\u4e2d\u3002\u8fd8\u6709\u4e00\u4e9b\u7f55\u89c1\u548c\u6781\u7f55\u89c1\u7684\u57fa\u56e0\u7ec4\u53d8\u5f02\u672a\u88ab\u8ba1\u5165\u98ce\u9669\u8ba1\u7b97\u4e2d\uff0c\u4f8b\u5982 DNA \u4e2d\u6838\u82f7\u9178\u7684\u63d2\u5165-\u7f3a\u5931 (indel) \u4f1a\u4ea7\u751f\u7a81\u53d8\uff0c\u6216\u8005 DNA \u6392\u5217\u7684\u53d8\u5316\uff08\u800c\u4e0d\u4ec5\u4ec5\u662f\u5355\u6838\u82f7\u9178\u53d8\u5316\uff09\u4f1a\u5bfc\u81f4\u7ed3\u6784\u53d8\u5f02\u3002\u6b64\u5916\uff0c\u86cb\u767d\u8d28\u7ec4\u5b66\u3001\u4ee3\u8c22\u7ec4\u5b66\u548c\u8868\u89c2\u57fa\u56e0\u7ec4\u5b66\u8c31\u4ee5\u53ca\u5fae\u751f\u7269\u7ec4\u3001\u514d\u75ab\u7ec4\u548c\u66b4\u9732\u7ec4\uff08\u73af\u5883\u66b4\u9732\uff09\u4e5f\u5b58\u5728\u5dee\u5f02\u3002<\/p>\n<p>2000 \u5e74\uff0c\u4e2d\u7f8e\u82f1\u65e5\u5fb7\u6cd5\uff16\u56fd\u5ba3\u5e03\u4eba\u7c7b\u57fa\u56e0\u7ec4\u5de5\u4f5c\u8349\u56fe\u7ed8\u5236\u5b8c\u6210\u3002\u5df2\u7ed8\u5236\u51fa\u4eba\u4f53 97% \u7684\u57fa\u56e0\u7ec4\uff0c\u5176\u4e2d 85 %\u7684\u57fa\u56e0\u7ec4\u5e8f\u5217\u5f97\u5230\u4e86\u7cbe\u786e\u6d4b\u5b9a\uff0c\u5305\u542b\u4e86\u4eba\u4f53\u7ea6 30 \u4ebf\u4e2a\u78b1\u57fa\u5bf9\u7684\u6b63\u786e\u6392\u5e8f\u3002<\/p>\n<p>\u4eba\u7c7b\u57fa\u56e0\u7ec4\u4e2d\u7ea6\u6709 20,000 \u4e2a\u86cb\u767d\u8d28\u7f16\u7801\u57fa\u56e0\uff0c\u800c\u4eba\u4f53\u4e2d\u5374\u6709\u8d85\u8fc7 100,000 \u79cd\u4e0d\u540c\u7684\u86cb\u767d\u8d28\uff0c\u5e76\u4e14\u7531\u4e8e\u53ef\u53d8\u526a\u63a5\uff0c\u4eba\u4f53\u4e2d\u8fd8\u5b58\u5728\u6570\u5341\u4e07\u79cd\u86cb\u767d\u8d28\u5f02\u6784\u4f53\uff08\u53d8\u4f53\uff09\u3002\u80fd\u591f\u68c0\u6d4b\u5176\u4e2d\u7684\u5927\u90e8\u5206\u86cb\u767d\u8d28\u662f\u65e0\u5047\u8bbe\u7814\u7a76\u7684\u57fa\u7840\uff0c\u5373\u52aa\u529b\u6536\u96c6\u6570\u636e\u5e76\u76f2\u76ee\u5bfb\u627e\u6a21\u5f0f\uff0c\u800c\u4e0d\u662f\u5047\u8bbe\u5b58\u5728\u67d0\u4e9b\u6a21\u5f0f\u7136\u540e\u5bfb\u627e\u5b83\u4eec\u3002\u8fd9\u79cd\u65b9\u6cd5\u4e0e\u673a\u5668\u5b66\u4e60\u5206\u6790\u4e00\u8d77\uff0c\u5f15\u53d1\u4e86\u4e00\u573a\u7406\u89e3\u75be\u75c5\u57fa\u7840\u7684\u9769\u547d\u3002<\/p>\n<p>\u6700\u8fd1\u51e0\u9879\u9ad8\u901a\u91cf\u86cb\u767d\u8d28\u7ec4\u5b66\u7814\u7a76\uff0c\u5728\u5668\u5b98\u548c\u5168\u8eab\u5c42\u9762\u90fd\u5177\u6709\u542f\u53d1\u610f\u4e49\u3002\u4e09\u9879\u7814\u7a76\u63a2\u8ba8\u4e86\u5668\u5b98\u7279\u5f02\u6027\u86cb\u767d\u8d28\u52a8\u529b\u5b66\u3002<\/p>\n<p>\u65af\u5766\u798f\u5927\u5b66\u7814\u7a76\u56e2\u961f\u5c06 5,676 \u540d\u6210\u5e74\u4eba\u5206\u4e3a\u4e94\u4e2a\u72ec\u7acb\u961f\u5217\uff08\u4e09\u7ec4\u4e3a\u5065\u5eb7\u53c2\u4e0e\u8005\uff0c\u4e24\u7ec4\u4e3a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\uff09\u4e2d\u7b5b\u9009\u51fa\u6570\u636e\uff0c\u6765\u8bc4\u4f30\u8fd1 5000 \u79cd\u8840\u6d46\u86cb\u767d\uff08\u5e76\u8fdb\u884c\u4e86 5 \u5e74\u7684\u968f\u8bbf\uff09\u3002<\/p>\n<p>\u4f7f\u7528\u673a\u5668\u5b66\u4e60\u6a21\u578b\uff0c\u786e\u5b9a\u4e86 11 \u4e2a\u5668\u5b98\u7279\u6709\u7684\u86cb\u767d\u8d28\uff0c\u5e76\u901a\u8fc7\u6bd4\u8f83\u751f\u7269\u5e74\u9f84\u548c\u5b9e\u9645\u5e74\u9f84\u5f97\u51fa\u300c\u5668\u5b98\u5e74\u9f84\u5dee\u8ddd\u300d\u3002\u5927\u7ea6\u4e94\u5206\u4e4b\u4e00\u7684\u4eba\u81f3\u5c11\u6709\u4e00\u4e2a\u5668\u5b98\u662f\u8d85\u9f84\u8005\uff0c\u56e0\u6b64\uff0c\u5668\u5b98\u5728\u751f\u7406\u548c\u529f\u80fd\u4e0a\u90fd\u6bd4\u4eba\u7684\u5b9e\u9645\u5e74\u9f84\u5927\u5f97\u591a\uff0c2% \u7684\u4eba\u6709\u591a\u4e2a\u5668\u5b98\u662f\u8d85\u9f84\u8005\u3002\u5bf9\u4e8e\u8fd9 11 \u4e2a\u5668\u5b98\u4e2d\u7684\u6bcf\u4e00\u4e2a\uff0c\u5e74\u9f84\u5dee\u8ddd\u90fd\u4e0e\u6b7b\u4ea1\u98ce\u9669\u589e\u52a0\u6709\u5173\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-02aaae7c10a1311a08d36e813f3931ba.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-02aaae7c10a1311a08d36e813f3931ba.png\"><\/a><\/p>\n<section>\u8bba\u6587\u94fe\u63a5\uff1a<em>https:\/\/www.nature.com\/articles\/s41586-023-06802-1<\/em><\/section>\n<p>\u968f\u540e\u7684\u4e24\u9879\u7814\u7a76\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u4e86\u8fd9\u4e00\u53d1\u73b0\u3002<\/p>\n<p>\u5728\u54c8\u4f5b\u533b\u5b66\u9662\u7684\u9884\u5370\u8bba\u6587\u4e2d\uff0c\u4ed6\u4eec\u5bf9 53,000 \u540d\u82f1\u56fd\u751f\u7269\u6837\u672c\u5e93\uff08UK Biobank\uff09\u53c2\u4e0e\u8005\u7684\u7ea6 3000 \u79cd\u8840\u6d46\u86cb\u767d\u8fdb\u884c\u4e86\u8bc4\u4f30\u3002\u501f\u52a9\u673a\u5668\u5b66\u4e60\uff0c\u4ed6\u4eec\u5b9a\u4e49\u4e86\u4e03\u4e2a\u5668\u5b98\u7279\u5f02\u6027\u8870\u8001\u65f6\u949f\u3002\u5438\u70df\u7b49\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u4e0e\u6240\u6709\u4e03\u4e2a\u5668\u5b98\u7684\u8870\u8001\u901f\u5ea6\u52a0\u5feb\u6709\u5173\uff0c\u996e\u9152\u4e5f\u4f1a\u5bfc\u81f4\u80a0\u9053\u8870\u8001\u3002\u5668\u5b98\u8870\u8001\u8fd8\u4e0e\u8bb8\u591a\u5176\u4ed6\u56e0\u7d20\u6709\u5173\uff0c\u5305\u62ec\u5404\u79cd\u98df\u7269\u3001\u836f\u7269\u548c\u804c\u4e1a\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-6bcf3d317d2efad7771399811b5288df.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-6bcf3d317d2efad7771399811b5288df.png\"><\/a><\/p>\n<section>\u8bba\u6587\u94fe\u63a5\uff1a<em>https:\/\/www.medrxiv.org\/content\/10.1101\/2024.04.08.24305469v1<\/em><\/section>\n<p>\u7b2c\u4e09\u9879\u7814\u7a76\u4e5f\u662f\u7531\u65af\u5766\u798f\u5927\u5b66\u8fdb\u884c\u7684\uff0c\u4ed6\u4eec\u68c0\u6d4b\u4e86 44,000 \u540d UK Biobank \u53c2\u4e0e\u8005\u7684 3000 \u79cd\u8840\u6d46\u86cb\u767d\uff0c\u5e76\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86 11 \u4e2a\u5668\u5b98\u7279\u5f02\u6027\u8870\u8001\u65f6\u949f\u3002\u4e0e\u5438\u70df\u548c\u996e\u9152\u76f8\u6bd4\uff0c\u7edd\u7ecf\u540e\u96cc\u6fc0\u7d20\u66ff\u4ee3\u7597\u6cd5\u4e0e\u5927\u591a\u6570\u5668\u5b98\u7684\u8870\u8001\u901f\u5ea6\u51cf\u6162\u6709\u5173\u3002\u4e00\u4e2a\u503c\u5f97\u6ce8\u610f\u7684\u53d1\u73b0\u662f\uff0c\u5728\u957f\u8fbe 15 \u5e74\u7684\u968f\u8bbf\u4e2d\uff0c\u5927\u8111\u6216\u514d\u75ab\u7cfb\u7edf\u8870\u8001\u7f13\u6162\u4e0e\u751f\u5b58\u7387\u63d0\u9ad8\u6709\u5173\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-6438bc7fcf97bd8c29bb4f5c2628af0d.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-6438bc7fcf97bd8c29bb4f5c2628af0d.png\"><\/a><\/p>\n<section>\u8bba\u6587\u94fe\u63a5\uff1a<em>https:\/\/www.biorxiv.org\/content\/10.1101\/2024.06.07.597771v1<\/em><\/section>\n<p>\u8f6c\u5411\u5168\u8eab\u9ad8\u901a\u91cf\u86cb\u767d\u8d28\u7ec4\u5b66\uff0c\u725b\u6d25\u5927\u5b66\u56e2\u961f\u5206\u6790\u4e86 45,000 \u591a\u540d UK Biobank \u53c2\u4e0e\u8005\u7684\u8fd1 3000 \u79cd\u8840\u6d46\u86cb\u767d\uff0c\u5e76\u5728\u7ea6 4000 \u540d\u53c2\u4e0e\u8005\u7684\u4e2d\u56fd\u751f\u7269\u5e93\u548c\u8fd1 2000 \u4eba\u7684\u82ac\u5170\u751f\u7269\u5e93\u4e2d\u8fdb\u884c\u4e86\u8fdb\u4e00\u6b65\u7684\u4ea4\u53c9\u9a8c\u8bc1\uff0c\u6bcf\u4e2a\u961f\u5217\u81f3\u5c11\u8fdb\u884c\u4e86 11 \u5e74\u7684\u968f\u8bbf\u3002<\/p>\n<p>204 \u79cd\u86cb\u767d\u8d28\u7c07\u4e0d\u4ec5\u53ef\u4ee5\u51c6\u786e\u9884\u6d4b\u5b9e\u9645\u5e74\u9f84\uff0c\u800c\u4e14\u8fd8\u4e0e 18 \u79cd\u6162\u6027\u75be\u75c5\u6709\u5173\uff0c\u5305\u62ec\u56db\u79cd\u5e38\u89c1\u764c\u75c7\u3001\u591a\u91cd\u75be\u75c5\u548c\u5168\u56e0\u6b7b\u4ea1\u7387\uff08\u4efb\u4f55\u539f\u56e0\u5bfc\u81f4\u7684\u6b7b\u4ea1\uff09\u3002\u86cb\u767d\u8d28\u7ec4\u65f6\u949f\u5feb\u901f\u8870\u8001\u8005\uff08\u86cb\u767d\u8d28\u6a21\u5f0f\u8868\u660e\u8870\u8001\u901f\u5ea6\u5f02\u5e38\u5feb\u7684\u4e2a\u4f53\uff09\u60a3\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u98ce\u9669\u66f4\u9ad8\uff0c\u800c\u5728\u86cb\u767d\u8d28\u7ec4\u65f6\u949f\u7f13\u6162\u8870\u8001\u8005\u4e2d\uff0c\u4e0d\u5230 1% \u7684\u4eba\u60a3\u4e0a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-12d2f564645062de5c60fdaa8b8af9c7.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-12d2f564645062de5c60fdaa8b8af9c7.png\"><\/a><\/p>\n<section>\u8bba\u6587\u94fe\u63a5\uff1a<em>https:\/\/www.nature.com\/articles\/s41591-024-03164-7<\/em><\/section>\n<p>\u5251\u6865\u5927\u5b66\u53d1\u8868\u4e86\u4e24\u4efd\u5173\u4e8e\u4f7f\u7528\u4eba\u5de5\u667a\u80fd (AI) \u6a21\u578b\u8fdb\u884c\u5168\u8eab\u86cb\u767d\u8d28\u7ec4\u5b66\u7814\u7a76\u7684\u62a5\u544a\uff0c\u62d3\u5bbd\u4e86\u75be\u75c5\u9884\u6d4b\u9886\u57df\u3002<\/p>\n<p>\u5728\u8d85\u8fc7 25,000 \u540d\u53c2\u4e0e\u8005\u7684 EPIC-Norfolk \u961f\u5217\u4e2d\uff0c\u5927\u7ea6 3000 \u79cd\u8840\u6d46\u86cb\u767d\u88ab\u68c0\u6d4b\u51fa\u6765\uff0c\u5e76\u4e0e 13 \u79cd\u75be\u75c5\u548c\u5168\u56e0\u6b7b\u4ea1\u98ce\u9669\u76f8\u5173\u3002\u66f4\u5e7f\u6cdb\u5730\u8bf4\uff0c\u5728\u82f1\u56fd\u751f\u7269\u5e93\u7684 41,000 \u591a\u540d\u4e2a\u4f53\u4e2d\uff0c\u901a\u8fc7\u8bc4\u4f30\u76f8\u540c\u7684\u8840\u6d46\u86cb\u767d\u5e76\u5c06\u6570\u636e\u4e0e\u7535\u5b50\u5065\u5eb7\u8bb0\u5f55\u76f8\u7ed3\u5408\uff0c\u53d1\u73b0 218 \u79cd\u5e38\u89c1\u548c\u7f55\u89c1\u75be\u75c5\u4e2d\u7684 52 \u79cd\u7684\u98ce\u9669\u53ef\u9884\u6d4b\u6027\u7a0b\u5ea6\u5404\u4e0d\u76f8\u540c\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-8b358f099cdf3b80cacfa690b1e4ae46.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-8b358f099cdf3b80cacfa690b1e4ae46.png\"><\/a><\/p>\n<section>\u8bba\u6587\u94fe\u63a5\uff1a<em>https:\/\/www.nature.com\/articles\/s41591-019-0673-2<\/em><\/section>\n<p>\u5173\u4e8e\u8870\u8001\uff0c\u86cb\u767d\u8d28\u7ec4\u5b66\u7814\u7a76\u8868\u660e\u5b83\u4e0d\u662f\u4e00\u4e2a\u7ebf\u6027\u8fc7\u7a0b\u30022019 \u5e74\uff0c\u65af\u5766\u798f\u5927\u5b66\u7814\u7a76\u4eba\u5458\uff0c\u5728 4000 \u591a\u540d\u5e74\u9f84\u5728 18 \u81f3 95 \u5c81\u4e4b\u95f4\u7684\u4eba\u7fa4\u4e2d\uff0c\u5728\u8fd1 3000 \u79cd\u86cb\u767d\u8d28\u4e2d\uff0c\u6211\u4eec\u7684\u751f\u547d\u5468\u671f\u4e2d\u6709\u4e09\u4e2a\u86cb\u767d\u8d28\u7ec4\u5b66\u5cf0\uff0c\u5206\u522b\u5728 35 \u5c81\u300160 \u5c81\u548c 80 \u5c81\u5de6\u53f3\u3002\u6700\u8fd1\uff0c\u4e00\u9879\u591a\u7ec4\u5b66\u7814\u7a76\u8bc4\u4f30\u4e86 300 \u591a\u79cd\u86cb\u767d\u8d28\uff0c\u4f46\u4ec5\u9650\u4e8e 75 \u5c81\uff08\u5e76\u8fdb\u884c\u4e86 1.7 \u5e74\u7684\u77ed\u6682\u968f\u8bbf\uff09\uff0c\u53d1\u73b0\u86cb\u767d\u8d28\u7ec4\u5b66\u5cf0\u51fa\u73b0\u5728 44 \u5c81\u548c 61 \u5c81\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-bfacdb972a49261f15ed208104bdb951.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/10\/frc-bfacdb972a49261f15ed208104bdb951.png\"><\/a><\/p>\n<section>\u8bba\u6587\u94fe\u63a5\uff1a<em>https:\/\/www.nature.com\/articles\/s41591-019-0665-2<\/em><\/section>\n<p>SomaLogic \u516c\u53f8\u7814\u7a76\u4e86\u8fd1 17,0000 \u540d\u4e2a\u4f53\u4e2d\u7ea6 5000 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(APOE)\u00a0\u57fa\u56e0\u53d8\u5f02\u6709\u5173\u3002<\/p>\n<p>\u603b\u4e4b\uff0c\u8fd9\u4e9b\u7814\u7a76\u7a81\u51fa\u4e86\u68c0\u6d4b\u548c\u4e86\u89e3\u5927\u91cf\u8840\u6d46\u86cb\u767d\u7684\u5168\u65b0\u975e\u51e1\u80fd\u529b\u3002\u8fc4\u4eca\u4e3a\u6b62\u7684\u7814\u7a76\u5df2\u7ecf\u589e\u5f3a\u4e86\u6211\u4eec\u5bf9\u4eba\u7c7b\u8870\u8001\u8fc7\u7a0b\u7684\u7406\u89e3\uff0c\u786e\u5b9a\u4e86\u8bb8\u591a\u5668\u5b98\u7279\u5f02\u6027\u53d8\u5316\u53ca\u5176\u53ef\u80fd\u5982\u4f55\u5f97\u5230\u6709\u5229\u8c03\u8282\uff0c\u5e76\u63d0\u9ad8\u4e86\u4f7f\u7528\u86cb\u767d\u8d28\u7ec4\u5b66\u8bc4\u5206\u8bc4\u4f30\u5404\u79cd\u75be\u75c5\u98ce\u9669\u7684\u6f5c\u529b\u3002<\/p>\n<p>\u5f53\u7136\uff0c\u8fd9\u4ec5\u4ee3\u8868\u4e00\u5c42\u6570\u636e\uff0c\u901a\u8fc7\u4f7f\u7528\u591a\u6a21\u6001 AI \u5206\u6790\uff0c\u53ef\u4ee5\u4e0e\u7535\u5b50\u5065\u5eb7\u8bb0\u5f55\u3001\u57fa\u56e0\u7ec4\u98ce\u9669\u3001\u8868\u89c2\u9057\u4f20\u65f6\u949f\u3001\u708e\u75c7\u751f\u7269\u6807\u5fd7\u7269\u3001\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u3001\u514d\u75ab\u7cfb\u7edf\u529f\u80fd\u548c\u73af\u5883\u66b4\u9732\u6b63\u4ea4\u6574\u5408\u3002<\/p>\n<p>\u9ad8\u901a\u91cf\u86cb\u767d\u8d28\u7ec4\u5b66\u8bc4\u4f30\u7684\u4e00\u4e2a\u9650\u5236\u662f\u8d39\u7528\uff0c\u6bcf\u4eba\u8d39\u7528\u4ece 500 \u7f8e\u5143\u5230 1000 \u7f8e\u5143\u4e0d\u7b49\u3002\u4f46\u7ecf\u8fc7\u9a8c\u8bc1\u7684\u86cb\u767d\u8d28\u7ec4\u5b50\u96c6\u53ef\u7528\u4e8e\u7279\u5b9a\u98ce\u9669\u8bc4\u4f30\uff0c\u56e0\u6b64\u6210\u672c\u53ef\u80fd\u4f1a\u4f4e\u5f97\u591a\u3002<\/p>\n<p>\u6b64\u65f6\u4e0d\u5bb9\u9519\u8fc7\u7684\u662f\uff0c\u6211\u4eec\u786e\u5b9e\u770b\u5230\u4e86\u86cb\u767d\u8d28\u7ec4\u5b66\u9886\u57df\u548c\u4eba\u5de5\u667a\u80fd\u7684\u4ee4\u4eba\u632f\u594b\u7684\u53d1\u5c55\uff0c\u5b83\u4eec\u5c06\u7ee7\u7eed\u53d1\u5c55\u5e76\u6700\u7ec8\u5728\u5e38\u89c4\u533b\u7597\u4fdd\u5065\u4e2d\u627e\u5230\u81ea\u5df1\u7684\u4f4d\u7f6e\u3002<\/p>\n<p>\u53c2\u8003\u5185\u5bb9\uff1a<em>https:\/\/www.science.org\/doi\/10.1126\/science.ads5749<\/em><\/p>\n<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2024-10-05-2\" target=\"_blank\">Science 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[&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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