{"id":36045,"date":"2025-01-04T21:00:16","date_gmt":"2025-01-04T13:00:16","guid":{"rendered":"https:\/\/17aitech.com\/?p=36045"},"modified":"2025-01-04T21:00:16","modified_gmt":"2025-01-04T13:00:16","slug":"ai%e5%8f%91%e7%8e%b0%e8%b6%8516%e4%b8%87%e7%a7%8d%e6%96%b0rna%e7%97%85%e6%af%92%ef%bc%9f%e9%98%bf%e9%87%8c%e4%ba%91%e3%80%81%e4%b8%ad%e5%b1%b1%e5%a4%a7%e5%ad%a6%e5%90%88%e4%bd%9c%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=36045","title":{"rendered":"AI\u53d1\u73b0\u8d8516\u4e07\u79cd\u65b0RNA\u75c5\u6bd2\uff1f\u963f\u91cc\u4e91\u3001\u4e2d\u5c71\u5927\u5b66\u5408\u4f5c\u7814\u7a76\u767bCell"},"content":{"rendered":"

\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:AI\u53d1\u73b0\u8d8516\u4e07\u79cd\u65b0RNA\u75c5\u6bd2\uff1f\u963f\u91cc\u4e91\u3001\u4e2d\u5c71\u5927\u5b66\u5408\u4f5c\u7814\u7a76\u767bCell<\/a><\/p>\n

<\/a><\/section>\n

\u7f16\u8f91 | \u841d\u535c\u76ae<\/p>\n

\u4eba\u5de5\u667a\u80fd<\/mark>\uff08AI\uff09\u5df2\u88ab\u7528\u6765\u63ed\u793a\u5730\u7403\u5404\u4e2a\u89d2\u843d\u7684\u591a\u79cd\u57fa\u672c\u751f\u547d\u4f53\u3002<\/p>\n

\u963f\u91cc\u4e91<\/mark>\u3001\u4e2d\u5c71\u5927\u5b66\u3001\u6089\u5c3c\u5927\u5b66\u7b49\u673a\u6784\u7684\u5408\u4f5c\u56e2\u961f\u5f00\u53d1\u4e86\u4e00\u79cd\u6df1\u5ea6\u5b66\u4e60<\/mark>\u7b97\u6cd5\uff0c\u79f0\u4e3a LucaProt\uff0c\u7528\u4e8e\u53d1\u73b0\u6765\u81ea\u5168\u7403\u4e0d\u540c\u751f\u6001\u7cfb\u7edf\u7684 10,487 \u4e2a\u5b8f\u8f6c\u5f55\u7ec4\u4e2d\u9ad8\u5ea6\u5206\u5316\u7684 RNA \u4f9d\u8d56\u6027 RNA \u805a\u5408\u9176 (RdRP) \u5e8f\u5217\u3002LucaProt \u6574\u5408\u4e86\u5e8f\u5217\u548c\u9884\u6d4b\u7ed3\u6784\u4fe1\u606f\uff0c\u4ece\u800c\u80fd\u591f\u51c6\u786e\u68c0\u6d4b RdRP \u5e8f\u5217\u3002<\/p>\n

\u501f\u52a9 LucaProt\uff0c\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e86\u603b\u5171 161,979 \u79cd\u65b0\u7684 RNA \u75c5\u6bd2\uff0c\u8ba4\u4e3a\u8fd9\u5c06\u6781\u5927\u5730\u6539\u5584\u5730\u7403\u751f\u547d\u7684\u7ed8\u5236\uff0c\u5e76\u6709\u52a9\u4e8e\u8bc6\u522b\u6570\u767e\u4e07\u79cd\u5c1a\u672a\u9274\u5b9a\u7684\u75c5\u6bd2\u3002<\/p>\n

\u65b0\u53d1\u73b0\u7684 RNA \u75c5\u6bd2\u5b58\u5728\u4e8e\u5404\u79cd\u73af\u5883\u4e2d\uff0c\u5305\u62ec\u7a7a\u6c14\u3001\u6e29\u6cc9\u548c\u70ed\u6db2\u55b7\u53e3\uff0c\u75c5\u6bd2\u591a\u6837\u6027\u548c\u4e30\u5ea6\u5728\u4e0d\u540c\u7684\u751f\u6001\u7cfb\u7edf\u4e2d\u5b58\u5728\u5f88\u5927\u5dee\u5f02\u3002\u8fd9\u9879\u7814\u7a76\u63a8\u52a8\u4e86\u75c5\u6bd2\u7684\u53d1\u73b0\uff0c\u7a81\u51fa\u4e86\u75c5\u6bd2\u5708\u7684\u89c4\u6a21\uff0c\u5e76\u63d0\u4f9b\u4e86\u66f4\u597d\u5730\u8bb0\u5f55\u5168\u7403 RNA \u75c5\u6bd2\u7ec4\u7684\u8ba1\u7b97\u5de5\u5177\u3002<\/p>\n

\u8be5\u7814\u7a76\u4ee5\u300cUsing artificial intelligence to document the hidden RNA virosphere<\/em>\u300d\u4e3a\u9898\uff0c\u4e8e 2024 \u5e74 10 \u6708 9 \u65e5\u53d1\u5e03\u5728\u300aCell<\/em>\u300b\u3002<\/p>\n

<\/a><\/p>\n

\u8bba\u6587\u94fe\u63a5\uff1ahttps:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(24)01085-7<\/em><\/p>\n

\u300c\u8fd9\u9879\u7814\u7a76\u4e3a\u6211\u4eec\u63ed\u793a\u4e86\u5730\u7403\u751f\u547d\u4e2d\u4e0d\u4e3a\u4eba\u77e5\u7684\u4e00\u90e8\u5206\uff0c\u63ed\u793a\u4e86\u60ca\u4eba\u7684\u751f\u7269\u591a\u6837\u6027\u3002\u300d\u6587\u7ae0\u7684\u901a\u8baf\u4f5c\u8005\u4e4b\u4e00\u3001\u6089\u5c3c\u5927\u5b66\u7684 Edwards Holmes \u6559\u6388\u8bf4\uff0c\u300c\u8fd9\u662f\u5355\u9879\u7814\u7a76\u4e2d\u53d1\u73b0\u7684\u65b0\u75c5\u6bd2\u79cd\u7c7b\u6570\u91cf\u6700\u591a\u7684\u4e00\u6b21\uff0c\u6781\u5927\u5730\u6269\u5c55\u4e86\u6211\u4eec\u5bf9\u4eba\u7c7b\u81ea\u8eab\u75c5\u6bd2\u7684\u8ba4\u8bc6\u3002\u300d<\/p>\n

\u300c\u4e00\u4e0b\u5b50\u53d1\u73b0\u8fd9\u4e48\u591a\u65b0\u75c5\u6bd2\u771f\u662f\u4ee4\u4eba\u96be\u4ee5\u7f6e\u4fe1\uff0c\u8fd9\u53ea\u662f\u51b0\u5c71\u4e00\u89d2\uff0c\u5f00\u542f\u4e86\u4e00\u4e2a\u63a2\u7d22\u7684\u4e16\u754c\u3002\u8fd8\u6709\u6570\u767e\u4e07\u79cd\u75c5\u6bd2\u6709\u5f85\u53d1\u73b0\uff0c\u6211\u4eec\u53ef\u4ee5\u7528\u540c\u6837\u7684\u65b9\u6cd5\u6765\u8bc6\u522b\u7ec6\u83cc\u548c\u5bc4\u751f\u866b\u3002\u300d<\/p>\n

Holmes \u6559\u6388\u8bf4\uff1a\u300c\u6781\u7aef\u73af\u5883\u643a\u5e26\u5982\u6b64\u591a\u7c7b\u578b\u7684\u75c5\u6bd2\uff0c\u53ea\u662f\u5b83\u4eec\u60ca\u4eba\u7684\u591a\u6837\u6027\u548c\u5728\u6700\u6076\u52a3\u73af\u5883\u4e2d\u751f\u5b58\u7684\u97e7\u6027\u7684\u53e6\u4e00\u4e2a\u4f8b\u5b50\uff0c\u53ef\u80fd\u4e3a\u6211\u4eec\u63d0\u4f9b\u6709\u5173\u75c5\u6bd2\u548c\u5176\u4ed6\u57fa\u672c\u751f\u547d\u5f62\u5f0f\u5982\u4f55\u4ea7\u751f\u7684\u7ebf\u7d22\u3002\u300d<\/p>\n

LucaProt \u662f\u4e00\u79cd\u57fa\u4e8e Transformer \u7684 RNA \u75c5\u6bd2\u53d1\u73b0\u5de5\u5177\uff0c\u8be5\u5de5\u5177\u5229\u7528\u86cb\u767d\u8d28\u5e8f\u5217\u548c\u75c5\u6bd2 RdRP \u5e8f\u5217\u7684\u7ed3\u6784\u7279\u5f81\u3002\u8be5\u5de5\u5177\u5e94\u7528\u4e8e\u5305\u542b\u6765\u81ea\u4e0d\u540c\u751f\u6001\u7cfb\u7edf\u7684 10,487 \u4e2a\u5b8f\u8f6c\u5f55\u7ec4\u7684\u6570\u636e\u96c6\u3002<\/p>\n

\u4e3a\u4e86\u9a8c\u8bc1\u548c\u8fdb\u884c\u6bd4\u8f83\u5206\u6790\uff0c\u4f7f\u7528\u5176\u4ed6\u53ef\u7528\u7684\u751f\u7269\u4fe1\u606f\u5b66\u5de5\u5177\u5904\u7406\u4e86\u540c\u4e00\u6570\u636e\u96c6\uff0c\u5e76\u4f7f\u7528 DNA \u548c RNA \u6d4b\u5e8f\u5206\u6790\u4e86 50 \u4e2a\u6837\u672c\u3002<\/p>\n

\u901a\u8fc7\u5c06\u8be5\u5de5\u5177\u4e0e\u5927\u91cf\u5e8f\u5217\u6570\u636e\u7ed3\u5408\u4f7f\u7528\uff0c\u7814\u7a76\u4eba\u5458\u5c55\u793a\u4e86\u4eba\u5de5\u667a\u80fd<\/mark>\u5982\u4f55\u51c6\u786e\u6709\u6548\u5730\u68c0\u6d4b\u8868\u73b0\u51fa\u8d85\u51fa\u4f20\u7edf\u57fa\u4e8e\u76f8\u4f3c\u6027\u7684\u65b9\u6cd5\u80fd\u529b\u7684\u9057\u4f20\u5dee\u5f02\u7684 RNA \u75c5\u6bd2\u3002<\/p>\n

\u5982\u679c\u4e0d\u5b9e\u65bd\u7ed3\u6784\u6a21\u578b\uff0cLucaProt \u5728\u6d4b\u8bd5\u6570\u636e\u96c6\u4e0a\u7684\u7279\u5f02\u6027\u548c\u51c6\u786e\u6027\u5206\u522b\u53ea\u6709 41.8% \u548c 94.9%\uff0c\u5e76\u4e14\u53ea\u80fd\u68c0\u6d4b\u5230 44.5% \u7684\u9884\u6d4b RdRP \u86cb\u767d\u3002<\/p>\n

\u56e0\u6b64\uff0c\u5728\u8bc6\u522b\u9ad8\u5ea6\u5206\u5316\u7684 RNA \u75c5\u6bd2\u65f6\uff0cRdRP \u7ed3\u6784\u7684\u4fdd\u5b88\u6027\u6bd4 RdRP \u5e8f\u5217\u7684\u91cd\u8981\u6027\u66f4\u91cd\u8981\u3002<\/p>\n

<\/a><\/p>\n

\u56fe\u793a\uff1a\u6574\u4f53\u6982\u8ff0\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/section>\n

\u7814\u7a76\u4eba\u5458\u9274\u5b9a\u51fa 161,979 \u79cd\u6f5c\u5728 RNA \u75c5\u6bd2\u79cd\u7c7b\u548c 180 \u4e2a RNA \u75c5\u6bd2\u8d85\u7fa4\uff0c\u5176\u4e2d\u5305\u62ec\u8bb8\u591a\u4e4b\u524d\u7814\u7a76\u4e0d\u8db3\u7684\u7fa4\u4f53\uff0c\u4ee5\u53ca\u57fa\u56e0\u7ec4\u957f\u5ea6\u6781\u957f\uff08\u957f\u8fbe 47,250 \u4e2a\u6838\u82f7\u9178\uff09\u4e14\u57fa\u56e0\u7ec4\u590d\u6742\u7684 RNA \u75c5\u6bd2\u3002<\/p>\n

\u8fd9\u4e9b\u65b0\u578b RNA \u75c5\u6bd2\u7684\u4e00\u4e2a\u5b50\u96c6\u901a\u8fc7 RT-PCR \u548c RNA\/DNA \u6d4b\u5e8f\u5f97\u5230\u786e\u8ba4\u3002<\/p>\n

\u603b\u4e4b\uff0c\u7814\u7a76\u4eba\u5458\u5efa\u7acb\u4e86\u4e00\u4e2a\u7528\u4e8e\u5927\u89c4\u6a21 RNA \u75c5\u6bd2\u53d1\u73b0\u7684 AI \u6846\u67b6\u8303\u5f0f\uff0c\u4e00\u65e6\u51c6\u5907\u597d\u8bad\u7ec3\u6570\u636e\u96c6\uff0c\u5c31\u53ef\u4ee5\u5f88\u5bb9\u6613\u5730\u6269\u5c55\u5230\u5bf9\u4efb\u4f55\u751f\u7269\u300c\u6697\u7269\u8d28\u300d\u7684\u51c6\u786e\u63cf\u8ff0\u3002<\/p>\n

\u300c\u8fd9\u4e9b\u75c5\u6bd2\u4e2d\u7684\u7edd\u5927\u591a\u6570\u90fd\u5df2\u7ecf\u6d4b\u5e8f\u5e76\u5b58\u50a8\u5728\u516c\u5171\u6570\u636e\u5e93<\/mark>\u4e2d\uff0c\u4f46\u5b83\u4eec\u7684\u5dee\u5f02\u592a\u5927\uff0c\u4ee5\u81f3\u4e8e\u6ca1\u4eba\u77e5\u9053\u5b83\u4eec\u662f\u4ec0\u4e48\uff0c\u300dHolmes \u6559\u6388\u8bf4\uff0c\u300c\u5b83\u4eec\u6784\u6210\u4e86\u901a\u5e38\u88ab\u79f0\u4e3a\u5e8f\u5217\u2018\u6697\u7269\u8d28\u2019\u7684\u4e1c\u897f\u3002\u6211\u4eec\u7684\u4eba\u5de5\u667a\u80fd<\/mark>\u65b9\u6cd5\u80fd\u591f\u7ec4\u7ec7\u548c\u5206\u7c7b\u6240\u6709\u8fd9\u4e9b\u4e0d\u540c\u7684\u4fe1\u606f\uff0c\u9996\u6b21\u63ed\u793a\u4e86\u8fd9\u79cd\u6697\u7269\u8d28\u7684\u542b\u4e49\u3002\u300d<\/p>\n

\u8bba\u6587\u7684\u901a\u8baf\u4f5c\u8005\u4e4b\u4e00\u3001\u4e2d\u5c71\u5927\u5b66\u7684\u65bd\u83bd\u6559\u6388\u8868\u793a\uff1a\u300c\u6211\u4eec\u8fc7\u53bb\u4f9d\u9760\u7e41\u7410\u7684\u751f\u7269\u4fe1\u606f\u5b66\u6d41\u7a0b\u6765\u53d1\u73b0\u75c5\u6bd2\uff0c\u8fd9\u9650\u5236\u4e86\u6211\u4eec\u53ef\u4ee5\u63a2\u7d22\u7684\u591a\u6837\u6027\u3002\u73b0\u5728\uff0c\u6211\u4eec\u6709\u4e86\u4e00\u4e2a\u66f4\u6709\u6548\u7684\u57fa\u4e8e\u4eba\u5de5\u667a\u80fd<\/mark>\u7684\u6a21\u578b\uff0c\u5b83\u63d0\u4f9b\u4e86\u5353\u8d8a\u7684\u7075\u654f\u5ea6\u548c\u7279\u5f02\u6027\uff0c\u540c\u65f6\u8ba9\u6211\u4eec\u80fd\u591f\u66f4\u6df1\u5165\u5730\u7814\u7a76\u75c5\u6bd2\u591a\u6837\u6027\u3002\u6211\u4eec\u8ba1\u5212\u5c06\u6b64\u6a21\u578b\u5e94\u7528\u4e8e\u5404\u79cd\u5e94\u7528\u3002\u300d<\/p>\n

<\/a><\/p>\n

\u56fe\u793a\uff1aRNA \u75c5\u6bd2\u5708\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/p>\n

\u7814\u7a76\u4eba\u5458\u5c06\u9274\u5b9a\u7684\u6240\u6709 RNA \u75c5\u6bd2\u5e8f\u5217\u5206\u4e3a\u7c07\u548c\u8d85\u7ec4\uff0c\u7136\u540e\u5c06\u8d85\u7ec4\u4e0e ICTV \u5b9a\u4e49\u7684\u75c5\u6bd2\u7eb2\u548c\u95e8\u8fdb\u884c\u6bd4\u8f83\u3002\u5728\u8fd9\u91cc\u9274\u5b9a\u7684\u8d85\u7ec4\u4e2d\uff0c\u53ea\u6709 21 \u4e2a\u5305\u542b ICTV \u76ee\u524d\u5206\u7c7b\u7684\u75c5\u6bd2\u95e8\/\u7eb2\uff0c\u56e0\u6b64\u4e0e\u6700\u65b0\u7684 ICTV \u62a5\u544a\u76f8\u6bd4\uff0c\u8d85\u7ec4\u6c34\u5e73\u7684 RNA \u75c5\u6bd2\u591a\u6837\u6027\u6269\u5927\u4e86 8.6 \u500d\uff0c\u8fc4\u4eca\u4e3a\u6b62\u63cf\u8ff0\u7684\u6240\u6709 RNA \u75c5\u6bd2\u7684\u591a\u6837\u6027\u6269\u5927\u4e86 1.5 \u500d\u3002<\/p>\n

\u8fd9\u6b21\u6269\u5c55\u65e2\u5305\u62ec\u73b0\u6709\u7684\u75c5\u6bd2\u8d85\u7fa4\uff0c\u4e5f\u5305\u62ec\u4e4b\u524d\u7684 RNA \u75c5\u6bd2\u53d1\u73b0\u9879\u76ee\u4e2d\u5f88\u5927\u7a0b\u5ea6\u4e0a\u88ab\u5ffd\u89c6\u7684 60 \u4e2a\u9ad8\u5ea6\u5206\u5316\u7684\u8d85\u7fa4\u3002<\/p>\n

\u8fd9\u91cc\u9274\u5b9a\u7684\u75c5\u6bd2\u8d85\u7fa4\u4e0e\u73b0\u6709\u7684\u95e8\uff08\u4f8b\u5982\uff0cNarna-Levi \u8d85\u7fa4\u7684 Lenarviricota \u95e8\uff09\u6216\u7c7b\uff08\u4f8b\u5982\uff0cAstro-Poty\u3001Hepe-Virga \u548c Flavi \u8d85\u7fa4\u7684 Stelpaviricetes\u3001Alsuviricetes \u548c Flasuviricetes \u7c7b\uff09\u5206\u7c7b\u7cfb\u7edf\u5927\u81f4\u76f8\u5f53\uff0c\u975e\u5e38\u5177\u6709\u591a\u6837\u6027\u3002<\/p>\n

\u867d\u7136\u8fd9\u91cc\u8bb0\u5f55\u4e86 RNA \u75c5\u6bd2\u591a\u6837\u6027\u7684\u5927\u5e45\u589e\u52a0\uff0c\u4f46\u6211\u4eec\u5bf9\u65b0\u53d1\u73b0\u75c5\u6bd2\u7684\u8fdb\u5316\u548c\u751f\u6001\u5b66\u7684\u4e86\u89e3\u4ecd\u7136\u5b58\u5728\u91cd\u5927\u5dee\u8ddd\u3002\u7279\u522b\u662f\uff0c\u5927\u591a\u6570\u5df2\u53d1\u73b0\u75c5\u6bd2\u7684\u5bbf\u4e3b\u4ecd\u7136\u672a\u77e5\u3002<\/p>\n

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\u76f8\u5173\u5185\u5bb9\uff1ahttps:\/\/phys.org\/news\/2024-10-hidden-virosphere-ai-virus-species.html<\/em><\/p>\n

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