{"id":36904,"date":"2025-01-20T23:01:54","date_gmt":"2025-01-20T15:01:54","guid":{"rendered":"https:\/\/17aitech.com\/?p=36904"},"modified":"2025-01-20T23:01:54","modified_gmt":"2025-01-20T15:01:54","slug":"%e5%87%86%e7%a1%ae%e3%80%81%e5%bf%ab%e9%80%9f%e5%9c%b0%e4%bb%8e%e5%a4%b4%e9%a2%84%e6%b5%8brna-3d%e7%bb%93%e6%9e%84%ef%bc%8c%e6%b8%af%e4%b8%ad%e5%a4%a7%e3%80%81%e5%a4%8d%e6%97%a6%e7%ad%89%e6%b7%b1","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=36904","title":{"rendered":"\u51c6\u786e\u3001\u5feb\u901f\u5730\u4ece\u5934\u9884\u6d4bRNA 3D\u7ed3\u6784\uff0c\u6e2f\u4e2d\u5927\u3001\u590d\u65e6\u7b49\u6df1\u5ea6\u5b66\u4e60\u65b9\u6cd5RhoFold+\u767bNature\u5b50\u520a"},"content":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2024-11-29-2\" target=\"_blank\">\u51c6\u786e\u3001\u5feb\u901f\u5730\u4ece\u5934\u9884\u6d4bRNA 3D\u7ed3\u6784\uff0c\u6e2f\u4e2d\u5927\u3001\u590d\u65e6\u7b49\u6df1\u5ea6\u5b66\u4e60\u65b9\u6cd5RhoFold+\u767bNature\u5b50\u520a<\/a><\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/11\/frc-85c1087c7394df08a53d87a4de715656.jpeg\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/11\/frc-85c1087c7394df08a53d87a4de715656.jpeg\"><\/a><\/section>\n<p>\u7f16\u8f91 | KX<\/p>\n<p>RNA \u5206\u5b50\u5728\u5206\u5b50\u751f\u7269\u5b66\u4e2d\u5fc3\u6cd5\u5219\u4e2d\u8d77\u5173\u952e\u4f5c\u7528\uff0cRNA \u7ed3\u6784\u5982\u4f55\u5f71\u54cd\u57fa\u56e0\u8c03\u63a7\u548c\u529f\u80fd\u4e00\u76f4\u662f\u7814\u7a76\u7684\u70ed\u95e8\u8bdd\u9898\u3002\u51c6\u786e\u9884\u6d4b RNA \u4e09\u7ef4 (3D) \u7ed3\u6784\u4ecd\u662f\u4e00\u4e2a\u96be\u9898\u3002RNA \u7684\u7ed3\u6784\u7075\u6d3b\u6027\u5bfc\u81f4\u5b9e\u9a8c\u786e\u5b9a\u7684\u6570\u636e\u7a00\u7f3a\uff0c\u4ece\u800c\u4f7f\u8ba1\u7b97\u9884\u6d4b\u5de5\u4f5c\u53d8\u5f97\u590d\u6742\u3002<\/p>\n<p>\u5728\u6b64\uff0c\u9999\u6e2f\u4e2d\u6587\u5927\u5b66\u3001\u590d\u65e6\u5927\u5b66\u3001\u54c8\u4f5b\u5927\u5b66\u3001\u667a\u5cea\u751f\u79d1\uff08Zelixir\uff09\u7b49\u591a\u673a\u6784\u56e2\u961f\u5408\u4f5c\uff0c\u63d0\u51fa\u4e00\u79cd\u57fa\u4e8e RNA \u8bed\u8a00\u6a21\u578b\u7684\u6df1\u5ea6\u5b66\u4e60\u65b9\u6cd5 RhoFold+\uff0c\u7528\u4e8e\u51c6\u786e\u3001\u5feb\u901f\u5730\u8fdb\u884c\u4ece\u5934\u9884\u6d4b RNA \u4e09\u7ef4\u7ed3\u6784\u3002<\/p>\n<p>\u901a\u8fc7\u96c6\u6210\u5728\u7ea6 2370 \u4e07\u4e2a RNA \u5e8f\u5217\u4e0a\u9884\u8bad\u7ec3\u7684 RNA \u8bed\u8a00\u6a21\u578b\uff0c\u5e76\u5229\u7528\u6280\u672f\u89e3\u51b3\u6570\u636e\u7a00\u7f3a\u95ee\u9898\uff0cRhoFold+ \u4e3a RNA 3D \u7ed3\u6784\u9884\u6d4b\u63d0\u4f9b\u4e86\u5b8c\u5168\u81ea\u52a8\u5316\u7684\u7aef\u5230\u7aef\u6d41\u7a0b\u3002<\/p>\n<p>RhoFold+ \u5728\u5355\u94fe RNA \u5efa\u6a21\u65b9\u9762\u8868\u73b0\u51fa\u5f88\u9ad8\u7684\u51c6\u786e\u6027\uff0c\u5728 RNA \u5bb6\u65cf\u548c\u7c7b\u578b\u4e4b\u95f4\u5177\u6709\u51fa\u8272\u7684\u6cdb\u5316\u80fd\u529b\uff0c\u540c\u65f6\u8fd8\u80fd\u591f\u6355\u6349\u87ba\u65cb\u95f4\u5939\u89d2\uff08IHA\uff09\u548c\u4e8c\u7ea7\u7ed3\u6784\u7b49\u5c40\u90e8\u7279\u5f81\u3002<\/p>\n<p>\u5bf9 RNA-Puzzles \u548c CASP15 \u5929\u7136 RNA \u9776\u6807\u7684\u56de\u987e\u6027\u8bc4\u4f30\u8868\u660e\uff0cRhoFold+ \u4f18\u4e8e\u5305\u62ec\u4eba\u7c7b\u4e13\u5bb6\u7ec4\u5728\u5185\u7684\u73b0\u6709\u65b9\u6cd5\u3002<\/p>\n<p>\u76f8\u5173\u7814\u7a76\u4ee5\u300c<em>Accurate RNA 3D structure prediction using a language model-based deep learning approach<\/em>\u300d\u4e3a\u9898\uff0c\u4e8e 11 \u6708 21 \u65e5\u53d1\u5e03\u5728\u300a<em>Nature Methods<\/em>\u300b\u4e0a\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/11\/frc-be9c8f20c42993653f63ccdb125fd86b.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/11\/frc-be9c8f20c42993653f63ccdb125fd86b.png\"><\/a><\/p>\n<section>\u8bba\u6587\u94fe\u63a5\uff1a<em>https:\/\/www.nature.com\/articles\/s41592-024-02487-0<\/em><\/section>\n<p>\u786e\u5b9a RNA 3D \u7ed3\u6784\u5bf9\u4e8e\u7406\u89e3\u5176\u529f\u80fd\uff0c\u4ee5\u53ca\u4e3a RNA \u9776\u5411\u836f\u7269\u5f00\u53d1\u548c\u5408\u6210\u751f\u7269\u5b66\u8bbe\u8ba1\u63d0\u4f9b\u4fe1\u606f\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<p>RNA \u5206\u5b50\u7684\u6784\u8c61\u7075\u6d3b\u6027\u4f7f\u5f97\u5b9e\u9a8c\u786e\u5b9a\u5176 3D \u7ed3\u6784\u5177\u6709\u6311\u6218\u6027\u3002\u622a\u81f3 2023 \u5e74 12 \u6708\uff0c\u5728\u86cb\u767d\u8d28\u6570\u636e\u5e93\uff08PDB\uff09\u4e2d\u7ea6 214,000 \u4e2a\u7ed3\u6784\u4e2d\uff0c\u4ec5 RNA \u7ed3\u6784\u5360\u4e0d\u5230 1.0%\uff0c\u800c\u542b RNA \u590d\u5408\u7269\u4ec5\u5360 2.1%\u3002<\/p>\n<p>\u8ba1\u7b97\u65b9\u6cd5\u5df2\u7ecf\u6210\u4e3a\u5229\u7528 RNA \u5e8f\u5217\u6570\u636e\u8fdb\u884c RNA 3D \u7ed3\u6784\u9884\u6d4b\u7684\u8865\u5145\u65b9\u6cd5\u3002\u4e3b\u8981\u5206\u4e3a\u4e24\u7c7b\uff1a\u57fa\u4e8e\u6a21\u677f\u7684\u5efa\u6a21\uff0c\u4f8b\u5982 ModeRNA \u548c RNAbuilder\uff0c\u53d7\u6a21\u677f\u5e93\u6709\u9650\u7684\u9650\u5236\uff1b\u4ee5\u53ca\u4ece\u5934\u9884\u6d4b\u65b9\u6cd5\uff0c\u5305\u62ec FARFAR2\u30013dRNA \u548c SimRNA\uff0c\u8fd9\u4e9b\u65b9\u6cd5\u66f4\u5177\u9884\u6d4b\u6027\uff0c\u4f46\u7531\u4e8e\u9700\u8981\u5927\u89c4\u6a21\u91c7\u6837\uff0c\u8ba1\u7b97\u91cf\u5f88\u5927\u3002<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_87 ez-toc-wrap-left-text counter-hierarchy ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u6587\u7ae0\u76ee\u5f55<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 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\u4e09\u7ef4\u7ed3\u6784<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/17aitech.com\/?p=36904\/#%E6%9C%AA%E6%9D%A5%E6%96%B9%E5%90%91\" >\u672a\u6765\u65b9\u5411<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E7%94%A8%E4%BA%8E_RNA_3D_%E7%BB%93%E6%9E%84%E9%A2%84%E6%B5%8B%E7%9A%84%E8%87%AA%E5%8A%A8%E5%8C%96%E7%AB%AF%E5%88%B0%E7%AB%AF%E5%B9%B3%E5%8F%B0\"><\/span><strong>\u7528\u4e8e RNA 3D \u7ed3\u6784\u9884\u6d4b\u7684\u81ea\u52a8\u5316\u7aef\u5230\u7aef\u5e73\u53f0<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>RhoFold+ \u7528\u4e8e\u51c6\u786e\u3001\u5feb\u901f\u5730\u4ece\u5934\u9884\u6d4b RNA 3D \u7ed3\u6784\u3002RhoFold+ \u662f\u5176\u524d\u8eab RhoFold \u7684\u5b8c\u5168\u81ea\u52a8\u5316\u548c\u53ef\u533a\u5206\u7684\u6539\u8fdb\uff0c\u5229\u7528\u6539\u8fdb\u7684\u591a\u5e8f\u5217\u6bd4\u5bf9\uff08MSA\uff09\u96c6\u6210\u548c\u5176\u4ed6\u529f\u80fd\u6765\u63d0\u9ad8\u6027\u80fd\u3002\u7814\u7a76\u7684\u4e3b\u8981\u91cd\u70b9\u662f\u786e\u5b9a\u4e0e\u5176\u4ed6\u5206\u5b50\u76f8\u4e92\u4f5c\u7528\u6709\u9650\u7684\u5355\u94fe RNA \u7684\u7ed3\u6784\u3002<\/p>\n<p>RhoFold+ \u7684\u5f00\u53d1\u662f\u7531 RNA \u7279\u5f02\u6027\u77e5\u8bc6\u548c\u73b0\u6709 RNA 3D \u7ed3\u6784\u6570\u636e\u7684\u5c40\u9650\u6027\u6307\u5bfc\u7684\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/11\/frc-0cee29bcef02b9808573aa2ae3f72619.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/11\/frc-0cee29bcef02b9808573aa2ae3f72619.png\"><\/a><\/p>\n<section>\u56fe\u793a\uff1aRhoFold+ \u7684\u67b6\u6784\u548c\u7528\u4e8e\u6027\u80fd\u8bc4\u4f30\u7684\u4efb\u52a1\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/section>\n<p>\u4e3a\u4e86\u6784\u5efa\u8bad\u7ec3\u6570\u636e\u96c6\uff0c\u7814\u7a76\u4eba\u5458\u4f7f\u7528 BGSU \u4ee3\u8868\u6027 RNA \u7ed3\u6784\u96c6\uff08\u7248\u672c 2022-04-13\uff09\u4ece PDB \u4e2d\u6574\u7406\u4e86\u6240\u6709\u53ef\u7528\u7684 RNA 3D \u7ed3\u6784\u3002\u7814\u7a76\u4e13\u6ce8\u4e8e\u5355\u94fe RNA\uff0c\u5e76\u901a\u8fc7\u5728 80% \u5e8f\u5217\u76f8\u4f3c\u6027\u9608\u503c\u4e0b\u4f7f\u7528 Cd-hit \u5bf9\u5e8f\u5217\u8fdb\u884c\u805a\u7c7b\u6765\u51cf\u5c11\u5197\u4f59\uff0c\u4ece\u800c\u4ece 5,583 \u6761 RNA \u94fe\u4e2d\u4ea7\u751f 782 \u4e2a\u72ec\u7279\u7684\u5e8f\u5217\u7c07\u3002<\/p>\n<p>\u7136\u540e\u901a\u8fc7\u7ba1\u9053 RhoFold+ \u5904\u7406\u8fd9\u4e9b RNA \u5e8f\u5217\u3002\u9996\u5148\uff0c\u4f7f\u7528\u5927\u578b RNA \u8bed\u8a00\u6a21\u578b RNA-FM \u5bf9\u5e8f\u5217\u8fdb\u884c\u8f6c\u6362\uff0c\u4ee5\u63d0\u53d6\u8fdb\u5316\u548c\u7ed3\u6784\u4e0a\u77e5\u60c5\u7684\u5d4c\u5165\u3002\u540c\u65f6\uff0c\u901a\u8fc7\u641c\u7d22\u5e7f\u6cdb\u7684\u5e8f\u5217\u6570\u636e\u5e93\u751f\u6210 MSA\u3002\u7136\u540e\u5c06\u5d4c\u5165\u548c MSA \u7279\u5f81\u8f93\u5165\u5230\u5176 transformer \u7f51\u7edc Rhoformer \u4e2d\uff0c\u5e76\u8fed\u4ee3\u4f18\u5316\u5341\u4e2a\u5468\u671f\u3002<\/p>\n<p>\u5728\u6b64\u4e4b\u540e\uff0c\u7ed3\u6784\u6a21\u5757\u91c7\u7528\u4e86\u51e0\u4f55\u611f\u77e5\u6ce8\u610f\u673a\u5236\u548c\u4e0d\u53d8\u70b9\u6ce8\u610f\u529b (IPA) \u6a21\u5757\u6765\u4f18\u5316 RNA \u4e3b\u94fe\u4e2d\u5173\u952e\u539f\u5b50\u7684\u5c40\u90e8\u6846\u67b6\u5750\u6807\u548c\u626d\u8f6c\u89d2\u3002\u5728\u91cd\u5efa\u5168\u539f\u5b50\u5750\u6807\u540e\uff0c\u5e94\u7528\u4e86\u7ed3\u6784\u7ea6\u675f\uff0c\u4f8b\u5982\u4e8c\u7ea7\u7ed3\u6784\u548c\u78b1\u57fa\u914d\u5bf9\u3002<\/p>\n<h1><span class=\"ez-toc-section\" id=\"%E5%87%86%E7%A1%AE%E3%80%81%E5%BF%AB%E9%80%9F%E5%9C%B0%E4%BB%8E%E5%A4%B4%E9%A2%84%E6%B5%8B_RNA_%E4%B8%89%E7%BB%B4%E7%BB%93%E6%9E%84\"><\/span><strong>\u51c6\u786e\u3001\u5feb\u901f\u5730\u4ece\u5934\u9884\u6d4b RNA \u4e09\u7ef4\u7ed3\u6784<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>\u5728\u5f00\u53d1 RhoFold+ \u4e4b\u540e\uff0c\u7814\u7a76\u4eba\u5458\u901a\u8fc7\u5e7f\u6cdb\u7684\u6d4b\u8bd5\u4e25\u683c\u5730\u5bf9\u5176\u6027\u80fd\u8fdb\u884c\u4e86\u57fa\u51c6\u6d4b\u8bd5\u548c\u8bc4\u4f30\u3002\u5305\u62ec RNA-Puzzles \u9776\u6807\u548c CASP15 \u5929\u7136 RNA \u9776\u6807\uff0c\u4ee5\u53ca\u6240\u6709\u53ef\u7528\u7684\u5b9e\u9a8c\u786e\u5b9a\u7684 RNA 3D \u7ed3\u6784\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/11\/frc-f64caca6bdda784f2347c4c3166b6a67.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2024\/11\/frc-f64caca6bdda784f2347c4c3166b6a67.png\"><\/a><\/p>\n<p>\u56fe\u793a\uff1a\u5bf9 RhoFold+ \u8fdb\u884c\u57fa\u51c6\u6d4b\u8bd5\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/p>\n<p>RhoFold+ \u5728 CASP15 \u5929\u7136 RNA \u9776\u6807\u4e0a\u663e\u793a\u51fa\u6700\u4f73\u7ed3\u679c\uff0c\u5e76\u5728 RNA-Puzzles \u7ed3\u6784\u4e2d\u5b9e\u73b0\u4e86\u4f4e\u4e8e 4 \u00c5 \u7684\u5e73\u5747\u5747\u65b9\u6839\u4f4d\u79fb\u3002RhoFold+ \u6548\u7387\u9ad8\uff0c\u53ea\u9700 0.14 \u79d2\u5373\u53ef\u751f\u6210\u51c6\u786e\u7684\u9884\u6d4b\uff0c\u65e0\u9700\u8017\u65f6\u7684\u91c7\u6837\u6216\u4f9d\u8d56\u4e13\u5bb6\u77e5\u8bc6\u3002\u5b83\u53ef\u4ee5\u5f88\u597d\u5730\u63a8\u5e7f\u5230\u4e0d\u540c\u7684\u6570\u636e\u96c6\uff0c\u5305\u62ec\u65b0\u786e\u5b9a\u7684 RNA 3D 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RNA \u7ed3\u6784\uff0c\u5c24\u5176\u662f\u5177\u6709\u591a\u4e2a\u87ba\u65cb\u6216\u5047\u7ed3\u7684 RNA \u7ed3\u6784\u3002\u7531\u4e8e\u8bb8\u591a RNA \u91c7\u7528\u591a\u79cd\u6784\u8c61\uff0c\u8be5\u6a21\u578b\u5728\u51c6\u786e\u6355\u6349 RNA \u5206\u5b50\u7684\u52a8\u6001\u7279\u6027\u65b9\u9762\u4e5f\u9762\u4e34\u6311\u6218\u3002<\/p>\n<p>\u6b64\u5916\uff0cRhoFold+ \u96be\u4ee5\u6a21\u62df\u6d89\u53ca\u914d\u4f53\u6216\u86cb\u767d\u8d28\u7684\u590d\u5408\u7269\u4e2d\u7684 RNA \u76f8\u4e92\u4f5c\u7528\uff0c\u800c\u8fd9\u5bf9\u4e8e\u7406\u89e3 RNA \u5728\u751f\u7269\u7cfb\u7edf\u4e2d\u7684\u529f\u80fd\u4f5c\u7528\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<p>\u4e0b\u4e00\u6b65\uff0c\u5c06\u6574\u5408\u63a2\u6d4b\u6570\u636e\u3001\u5206\u5b50\u52a8\u529b\u5b66\u548c\u80fd\u91cf\u51fd\u6570\u65b9\u6cd5\u7b49\uff0c\u4ee5\u63d0\u9ad8 RhoFold+ \u7684\u51c6\u786e\u6027\u3002\u6b64\u5916\uff0c\u589e\u5f3a MSA \u63d0\u53d6\u8fc7\u7a0b\u5e76\u63a2\u7d22\u9884\u6d4b RNA-\u86cb\u767d\u8d28\u548c RNA-\u914d\u4f53\u76f8\u4e92\u4f5c\u7528\u7684\u65b9\u6cd5\u5c06\u8fdb\u4e00\u6b65\u589e\u5f3a\u5176\u80fd\u529b\u3002<\/p>\n<p>\u53c2\u8003\u5185\u5bb9\uff1a<em>https:\/\/www.nature.com\/articles\/s41592-024-02488-z<\/em><\/p>\n<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2024-11-29-2\" target=\"_blank\">\u51c6\u786e\u3001\u5feb\u901f\u5730\u4ece\u5934\u9884\u6d4bRNA 3D\u7ed3\u6784\uff0c\u6e2f\u4e2d\u5927\u3001\u590d\u65e6\u7b49\u6df1\u5ea6\u5b66\u4e60\u65b9\u6cd5RhoFold+\u767bNature\u5b50\u520a<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:\u51c6\u786e\u3001\u5feb\u901f\u5730\u4ece\u5934\u9884\u6d4bR [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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