{"id":38207,"date":"2025-02-11T20:01:01","date_gmt":"2025-02-11T12:01:01","guid":{"rendered":"https:\/\/17aitech.com\/?p=38207"},"modified":"2025-02-11T20:01:01","modified_gmt":"2025-02-11T12:01:01","slug":"pnas%e9%a1%b6%e5%88%8a-%e6%8a%97%e4%bd%93%e4%b8%ad%e5%92%8c%e6%b4%bb%e6%80%a7%e6%8f%90%e5%8d%871000%e5%80%8d%ef%bc%8c%e7%99%be%e5%a5%a5%e5%87%a0%e4%bd%95%e7%94%9f%e6%88%90%e5%bc%8fai%e9%ab%98","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=38207","title":{"rendered":"PNAS\u9876\u520a | \u6297\u4f53\u4e2d\u548c\u6d3b\u6027\u63d0\u53471000\u500d\uff0c\u767e\u5965\u51e0\u4f55\u751f\u6210\u5f0fAI\u9ad8\u6548\u53cd\u51fb\u75c5\u6bd2\u65b0\u53d8\u79cd"},"content":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2025-02-10-10\" target=\"_blank\">PNAS\u9876\u520a | \u6297\u4f53\u4e2d\u548c\u6d3b\u6027\u63d0\u53471000\u500d\uff0c\u767e\u5965\u51e0\u4f55\u751f\u6210\u5f0fAI\u9ad8\u6548\u53cd\u51fb\u75c5\u6bd2\u65b0\u53d8\u79cd<\/a><\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-d5174b2bfb364980ee47f88ea5015db8.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-d5174b2bfb364980ee47f88ea5015db8.png\"><\/a><\/p>\n<p>\u7f16\u8f91\u4e28Science AI<\/p>\n<p>\u8fd1\u65e5\uff0c\u767e\u5965\u51e0\u4f55\uff08BioGeometry\uff09\u643a\u624b\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u836f\u5b66\u9662\u6731\u5efa\u4f1f\u56e2\u961f\uff0c\u57fa\u4e8e\u751f\u6210\u5f0f AI \u9a71\u52a8\u7684\u6297\u4f53\u4f18\u5316\u7b56\u7565\uff0c\u5728\u77ed\u65f6\u95f4\u5185\u7cbe\u51c6\u4f18\u5316 8G3 \u6297\u4f53\uff0c\u5b9e\u73b0\u5176\u5bf9\u6700\u65b0\u75c5\u6bd2\u53d8\u5f02\u682a JN.1 \u7684\u4e2d\u548c\u6d3b\u6027 1000-1500 \u500d\u7684\u8dc3\u5347\u3002\u76f8\u5173\u7814\u7a76\u6210\u679c\u5df2\u6b63\u5f0f\u53d1\u8868\u5728\u56fd\u9645\u9876\u7ea7\u671f\u520a\u300a\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u9662\u520a\u300b\uff08PNAS\uff09\u4e0a\u30101\u3011\uff0c\u7ee7 CR3022 \u6297\u4f53\u3001\u80bf\u7624\u6297\u539f 5T4 \u7eb3\u7c73\u6297\u4f53\u30102\u3011\u7b49\u591a\u4e2a\u4f18\u5316\u6848\u4f8b\u540e\uff0c\u518d\u6b21\u8bc1\u660e\u4e86\u751f\u6210\u5f0f AI \u9a71\u52a8\u6297\u4f53\u5de5\u7a0b\u7684\u5e7f\u6cdb\u9002\u7528\u6027\u548c\u53d8\u9769\u6f5c\u529b\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-2131f3cae460ec55f593dbd0d6c5bf55.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-2131f3cae460ec55f593dbd0d6c5bf55.png\"><\/a><\/p>\n<p>\u8bba\u6587\u5730\u5740\uff1a<em>https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2406659122<\/em><\/p>\n<p><strong>\u751f\u6210\u5f0f AI + \u6297\u4f53\u5de5\u7a0b\uff1a\u7cbe\u51c6\u4f18\u5316 8G3 \u6297\u4f53\uff0c\u4e2d\u548c\u6d3b\u6027\u63d0\u5347 1000-1500 \u500d<\/strong><\/p>\n<p>\u7531\u4e8e\u75c5\u6bd2\u57fa\u56e0\u7ec4\u7684\u5feb\u901f\u8fdb\u5316\u548c\u65b0\u53d8\u79cd\u7684\u4e0d\u65ad\u4ea7\u751f\u589e\u52a0\u4e86\u6cbb\u7597\u7684\u590d\u6742\u6027\uff0c\u5927\u591a\u6570\u65e9\u671f\u5f00\u53d1\u7684\u6297\u4f53\u5df2\u65e0\u6cd5\u7cbe\u51c6\u8bc6\u522b\u5e76\u6709\u6548\u7ed3\u5408\u76ee\u6807\uff0c\u5bfc\u81f4\u4e2d\u548c\u80fd\u529b\u5927\u5e45\u4e0b\u964d\u3002\u56e0\u6b64\uff0c\u7d27\u8ddf\u75c5\u6bd2\u6f14\u5316\u89c4\u5f8b\uff0c\u4f18\u5316\u73b0\u6709\u6297\u4f53\u5e76\u52a0\u901f\u5e7f\u8c31\u3001\u9ad8\u6548\u65b0\u6297\u4f53\u7684\u7814\u53d1\uff0c\u6210\u4e3a\u5e94\u5bf9\u8fd9\u4e00\u6311\u6218\u7684\u5173\u952e\u3002<\/p>\n<p>\u767e\u5965\u51e0\u4f55\u4e0e\u6731\u5efa\u4f1f\u56e2\u961f\u5229\u7528 GeoBiologics \u667a\u80fd\u86cb\u767d\u8ba1\u7b97\u5e73\u53f0\uff0c\u7ed3\u5408\u751f\u6210\u5f0f AI \u4e0e\u51e0\u4f55\u6df1\u5ea6\u5b66\u4e60\uff0c\u6784\u5efa\u4e86\u4e00\u5957\u9ad8\u6548\u7684\u6297\u4f53\u4f18\u5316\u6d41\u7a0b\u3002\u8be5\u65b9\u6cd5\u63d0\u4f9b\u4e86\u4e00\u79cd\u53ef\u590d\u7528\u7684\u6280\u672f\u8def\u5f84\uff0c\u52a0\u901f\u65b0\u578b\u6297\u4f53\u7684\u8bbe\u8ba1\u4e0e\u7b5b\u9009\u3002<\/p>\n<p>8G3 \u6297\u4f53\u662f\u6731\u5efa\u4f1f\u56e2\u961f\u4ece\u65e9\u671f\u5eb7\u590d\u8005\u4f53\u5185\u7b5b\u9009\u51fa\u7684\u5e7f\u8c31\u4e2d\u548c\u6297\u4f53\uff0c\u5728 BA.1 \u53ca\u591a\u4e2a\u53d8\u5f02\u682a\uff08Alpha\u3001Beta\u3001Gamma\u3001Delta\u3001Kappa\u3001BA.1\u3001BA.2\u3001BA.5\uff09\u4e2d\u5747\u5c55\u73b0\u51fa\u826f\u597d\u7684\u4e2d\u548c\u80fd\u529b\u3002\u7136\u800c\uff0c\u9762\u5bf9\u66f4\u665a\u51fa\u73b0\u7684 BA.2.75 \u53ca\u5176\u540e\u7eed\u6bd2\u682a\uff0c8G3 \u7684\u4e2d\u548c\u80fd\u529b\u660e\u663e\u4e0b\u964d\u3002\u9488\u5bf9\u6700\u65b0\u7684 JN.1 \u53d8\u5f02\u682a\uff082023 \u5e74 8 \u6708\u9996\u6b21\u53d1\u73b0\uff0c\u73b0\u4ecd\u88ab WHO \u5217\u4e3a\u9700\u5173\u6ce8\u53d8\u5f02\u682a VOC\uff09\uff0c\u5176\u4e2d\u548c\u80fd\u529b\u8dcc\u81f3\u539f\u59cb\u6c34\u5e73\u7684\u5343\u5206\u4e4b\u4e00\uff0c\u51e0\u4e4e\u5b8c\u5168\u5931\u6548\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-bcceb53791d812217c727c67af130a42.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-bcceb53791d812217c727c67af130a42.png\"><\/a><\/p>\n<p><em>\u539f\u59cb 8G3 \u6297\u4f53\u4e2d\u548c\u6d3b\u6027\u8868\u73b0\uff0c\u5176\u5bf9 JN.1 \u7684\u4e2d\u548c\u80fd\u529b\u663e\u8457\u4e0b\u964d<\/em><\/p>\n<p>\u4e3a\u4e86\u5e94\u5bf9\u8fd9\u4e00\u6311\u6218\uff0c\u767e\u5965\u51e0\u4f55\u4f9d\u6258 GeoBiologics \u4e00\u7ad9\u5f0f\u667a\u80fd\u86cb\u767d\u8ba1\u7b97\u5e73\u53f0\uff0c\u5bf9 8G3 \u6297\u4f53\u8fdb\u884c\u751f\u6210\u5f0f AI \u9a71\u52a8\u7684\u7cfb\u7edf\u6027\u4f18\u5316\u3002\u7814\u7a76\u56e2\u961f\u91c7\u7528\u4e86\u4e24\u8f6e\u4f18\u5316\u7b56\u7565\uff0c\u7cbe\u51c6\u63d0\u5347 8G3 \u7684\u4e2d\u548c\u6d3b\u6027\u53ca JN.1 \u6bd2\u682a\u7684\u4eb2\u548c\u529b\uff1a<\/p>\n<p><strong>\u7b2c\u4e00\u8f6e\u4f18\u5316\uff1aAI \u7cbe\u51c6\u7b5b\u9009\u5355\u70b9\u7a81\u53d8<\/strong><\/p>\n<p>AI \u7b97\u6cd5\u7cbe\u51c6\u9501\u5b9a 50 \u4e2a\u6f5c\u5728\u5355\u7a81\u53d8\u5206\u5b50\uff0c\u5e76\u4ece\u4e2d\u7b5b\u9009\u51fa\u591a\u4e2a\u80fd\u591f\u660e\u663e\u589e\u5f3a\u4e2d\u548c\u6d3b\u6027\u7684\u7a81\u53d8\u70b9\u4f4d\uff0c\u5176\u4e2d\u6700\u4f73\u5355\u70b9\u7a81\u53d8\u53ef\u5c06\u4e2d\u548c\u6d3b\u6027\u63d0\u5347 47 \u500d\u3002<\/p>\n<p><strong>\u7b2c\u4e8c\u8f6e\u4f18\u5316\uff1aAI \u9a71\u52a8\u7ec4\u5408\u7a81\u53d8<\/strong><\/p>\n<p>\u57fa\u4e8e\u7b2c\u4e00\u8f6e\u5b9e\u9a8c\u6570\u636e\uff0c\u767e\u5965\u51e0\u4f55\u5229\u7528 GeoBiologics \u5e73\u53f0\u8fdb\u4e00\u6b65\u5fae\u8c03\u81ea\u7814\u51e0\u4f55\u6df1\u5ea6\u5b66\u4e60\u7b97\u6cd5 GearBind\uff0c\u7cbe\u51c6\u9884\u6d4b\u5e76\u63a8\u8350\u6700\u4f73\u7684\u7ec4\u5408\u7a81\u53d8\u65b9\u6848\uff1a<\/p>\n<ul>\n<li>\u53cc\u70b9\u7a81\u53d8\uff08101F+96V\/96I\uff09\u4f7f\u4e2d\u548c\u6d3b\u6027\u63d0\u5347 100-300 \u500d<\/li>\n<li>\u56db\u70b9\u7a81\u53d8 \u4f7f\u4e2d\u548c\u6d3b\u6027\u63d0\u5347 1000-1500 \u500d\uff0c\u8fbe\u5230\u4e86 8.5 ng\/ml\uff0c\u751a\u81f3\u8d85\u8d8a 8G3 \u5bf9\u539f\u59cb\u682a\u7684\u4e2d\u548c\u80fd\u529b\u3002<\/li>\n<\/ul>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-7174f6b3ff7bcfa745061f24e33119e8.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-7174f6b3ff7bcfa745061f24e33119e8.png\"><\/a><\/p>\n<p><em>GeoBiologics \u5e73\u53f0\u9ad8\u6548\u4f18\u5316 8G3 \u6297\u4f53\uff0c\u4f7f\u5176\u5bf9 JN.1 \u7684\u4e2d\u548c\u80fd\u529b\u63d0\u5347 1500 \u500d<\/em><\/p>\n<p><strong>GearBind \u7684\u5353\u8d8a\u8868\u73b0\u65e9\u5df2\u6709\u8ff9\u53ef\u5faa<\/strong><\/p>\n<p>GearBind \u662f\u4e00\u79cd\u57fa\u4e8e\u51e0\u4f55\u56fe\u795e\u7ecf\u7f51\u7edc\u7684\u6297\u4f53\u4eb2\u548c\u529b\u4f18\u5316\u6a21\u578b\uff0c\u5176\u7814\u7a76\u6210\u679c\u5df2\u53d1\u8868\u4e8e\u53e6\u4e00\u56fd\u9645\u9876\u7ea7\u671f\u520a\u300aNature Communications\u300b\u30102\u3011\u3002\u8be5\u6a21\u578b\u7a81\u7834\u4e86\u4f20\u7edf\u6e7f\u5b9e\u9a8c\u7b5b\u9009\u7684\u5c40\u9650\uff0c\u80fd\u591f\u5728\u77ed\u77ed 1-2 \u8f6e\u4f18\u5316\u5185\uff0c\u5927\u5e45\u63d0\u9ad8\u6297\u4f53\u4eb2\u548c\u529b\uff0c\u51cf\u5c11 70% \u5b9e\u9a8c\u65f6\u95f4\uff0c\u8282\u7ea6 75% \u5b9e\u9a8c\u6210\u672c\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-7a06ece0f5e7e301eb276234dac4288a.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-7a06ece0f5e7e301eb276234dac4288a.png\"><\/a><\/p>\n<p><strong>GearBind \u7684\u6838\u5fc3\u521b\u65b0<\/strong><\/p>\n<ul>\n<li>\u591a\u91cd\u5173\u7cfb\u56fe\u795e\u7ecf\u7f51\u7edc\uff08Multi-Relational Graph Neural Network\uff09<\/li>\n<\/ul>\n<p>GearBind \u5728\u6297\u4f53 &#8211; \u6297\u539f\u7ed3\u5408\u754c\u9762\u6784\u5efa\u4e86\u4e00\u5f20\u5305\u542b\u591a\u5c42\u7ea7\u76f8\u4e92\u4f5c\u7528\u7684\u5168\u5c40\u4ea4\u4e92\u56fe\uff0c\u540c\u65f6\u6355\u6349\u539f\u5b50\u7ea7\u3001\u6b8b\u57fa\u7ea7\u3001\u6c28\u57fa\u9178\u7ea7\u7b49\u591a\u4e2a\u5c3a\u5ea6\u7684\u4fe1\u606f\uff0c\u4ece\u800c\u7cbe\u51c6\u5730\u9884\u6d4b\u7a81\u53d8\u4f53\u7684\u4eb2\u548c\u529b\u53d8\u5316\u3002<\/p>\n<ul>\n<li>\u591a\u7ea7\u6d88\u606f\u4f20\u9012\u673a\u5236\uff08Multi-Level Message Passing\uff09<\/li>\n<\/ul>\n<p>\u91c7\u7528\u591a\u7ea7\u4fe1\u606f\u4f20\u9012\u673a\u5236\uff0c\u7efc\u5408\u8003\u8651\u86cb\u767d\u7ed3\u6784\u90bb\u8fd1\u6027\u548c\u5e8f\u5217\u90bb\u8fd1\u6027\uff0c\u4f7f\u5f97\u6a21\u578b\u80fd\u4ece\u539f\u5b50\u3001\u539f\u5b50\u5bf9\u3001\u6c28\u57fa\u9178\u4e09\u4e2a\u5c3a\u5ea6\u5b66\u4e60\u6297\u4f53 &#8211; \u6297\u539f\u7ed3\u5408\u7279\u6027\uff0c\u7279\u522b\u662f\u5728\u6d89\u53ca\u4fa7\u94fe\u91cd\u6392\u548c\u6784\u8c61\u53d8\u5316\u7684\u60c5\u51b5\u4e0b\u5c55\u73b0\u51fa\u5353\u8d8a\u7684\u5efa\u6a21\u80fd\u529b\u3002<\/p>\n<ul>\n<li>\u5bf9\u6bd4\u5b66\u4e60\u9884\u8bad\u7ec3\uff08Contrastive Pretraining\uff09<\/li>\n<\/ul>\n<p>GearBind \u4f7f\u7528\u5bf9\u6bd4\u5b66\u4e60\u6280\u672f\uff0c\u5728\u5927\u91cf\u65e0\u76d1\u7763\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u6570\u636e\u4e0a\u8fdb\u884c\u4e86\u9884\u8bad\u7ec3\uff0c\u4f7f\u5176\u4e0d\u4ec5\u80fd\u7cbe\u51c6\u62df\u5408\u5df2\u77e5\u6297\u4f53\uff0c\u8fd8\u80fd\u6cdb\u5316\u5230\u4ece\u672a\u89c1\u8fc7\u7684\u65b0\u6297\u539f\u8868\u4f4d\uff0c\u63d0\u9ad8\u4e86\u5bf9\u6297\u4f53\u4f18\u5316\u7684\u9002\u5e94\u6027\u548c\u53ef\u6269\u5c55\u6027\u3002<\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-d0d62cb480cc7a66ca6a44401d927eae.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-d0d62cb480cc7a66ca6a44401d927eae.png\"><\/a><\/p>\n<p><em>\uff08\u4e0a\uff09GearBind \u51e0\u4f55\u795e\u7ecf\u7f51\u7edc\u67b6\u6784\u56fe\uff08\u4e0b\uff09GearBind \u9884\u8bad\u7ec3\u6d41\u7a0b\u56fe<\/em><\/p>\n<p>GearBind \u7684\u5353\u8d8a\u6027\u80fd\u4e0d\u4ec5\u9650\u4e8e 8G3 \u6297\u4f53\u4f18\u5316\uff0c\u5b83\u65e9\u5df2\u5728\u591a\u4e2a\u751f\u7269\u533b\u836f\u4efb\u52a1\u4e2d\u5c55\u73b0\u4e86\u5f3a\u5927\u7684\u5e94\u7528\u6f5c\u529b\u3002<\/p>\n<p>\u4f8b\u5982\uff0c\u5728\u9488\u5bf9 CR3022 \u6297\u4f53\u4f18\u5316\u5b9e\u9a8c\u4e2d\uff0cGearBind \u7cbe\u51c6\u9884\u6d4b\u4e86\u7a81\u53d8\u4f53\u7684\u4eb2\u548c\u529b\u53d8\u5316\uff0c\u5728 12 \u4e2a\u5176\u63a8\u8350\u7684\u70b9\u7a81\u53d8\u4e2d\u6709 9 \u4e2a\u5b9e\u73b0\u4e86\u4eb2\u548c\u529b\u63d0\u5347\uff0c\u51c6\u786e\u7387\u9ad8\u8fbe 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data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-1e11375ce0562ec7d68859255bbbd071.png\"><\/a><\/p>\n<p><em>\u5404 CR3022 \u7a81\u53d8\u4f53\u5bf9 Omicron Spike \u7684 ELISA \u7ed3\u5408\u5b9e\u9a8c\u7ed3\u679c<\/em><\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-5e9245a965b06de838fdb1281933fbf5.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/02\/frc-5e9245a965b06de838fdb1281933fbf5.png\"><\/a><\/p>\n<p><em>\u5404 CR3022 \u7a81\u53d8\u4f53\u5bf9 Omicron Spike \u7684 BLI 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\u533a\u7684\u6c28\u57fa\u9178\u4e5f\u4f1a\u4ea7\u751f\u4e00\u5343\u4f59\u4e2a\u7a81\u53d8\u4f53\u3002\u5982\u679c\u6269\u5c55\u5230\u53cc\u70b9\u3001\u4e09\u70b9\u751a\u81f3\u66f4\u590d\u6742\u7684\u7a81\u53d8\u5e93\uff0c\u5b9e\u9a8c\u5de5\u4f5c\u91cf\u5c06\u6307\u6570\u7ea7\u589e\u957f\uff0c\u4f7f\u5f97\u4f20\u7edf\u4f18\u5316\u7b56\u7565\u5728\u65b0\u6297\u4f53\u7814\u53d1\u4e2d\u663e\u5f97\u6349\u895f\u89c1\u8098\u3002<\/p>\n<p>\u672c\u7814\u7a76\u8868\u660e\uff0c\u751f\u6210\u5f0f AI \u5728\u6297\u4f53\u4f18\u5316\u3001\u751f\u7269\u5236\u9020\u7b49\u9886\u57df\u5c55\u73b0\u51fa\u5de8\u5927\u6f5c\u529b\u3002\u901a\u8fc7\u751f\u6210\u5f0f AI \u4ece\u5934\u8bbe\u8ba1\u3001\u591a\u529f\u80fd\u4f18\u5316\u86cb\u767d\uff0c\u53ef\u7cbe\u51c6\u8c03\u63a7\u86cb\u767d\u7684\u7ed3\u6784\u4e0e\u529f\u80fd\uff0c\u63d0\u9ad8\u6297\u4f53\u7684\u4eb2\u548c\u529b\u3001\u7a33\u5b9a\u6027\u548c\u5e7f\u8c31\u6027\u3002\u8fd9\u4e00\u6280\u672f\u6846\u67b6\u6709\u52a9\u4e8e\u5feb\u901f\u54cd\u5e94\u590d\u6742\u751f\u7269\u6311\u6218\uff0c\u63a8\u52a8\u667a\u80fd\u5316\u751f\u7269\u5236\u9020\u7684\u53d1\u5c55\uff0c\u4e3a\u4eba\u7c7b\u5065\u5eb7\u63d0\u4f9b\u66f4\u9ad8\u6548\u3001\u7cbe\u51c6\u3001\u53ef\u590d\u7528\u3001\u53ef\u6269\u5c55\u7684\u7b56\u7565\u548c\u65b9\u6cd5\u8bba\u3002<\/p>\n<p>\u53c2\u8003\u8d44\u6599:<\/p>\n<p>\u30101\u3011Y. Liao, H. Ma, Z. Wang, S. Wang, Y. He, Y. Chang, H. Zong, H. Tang, L. Wang, Y. Ke, H. Cai, P. Li, J. Tang, H. Chen, A. Drelich, B. Peng, J. Hsu, V. Tat, C.K. Tseng, J. Song, Y. Yuan, M. Wu, J. Liu, Y. Yue, X. Zhang, Z. Wang, L. Yang, J. Li, X. Ni, H. Li, Y. Xiang, Y. Bian, B. Zhang, H. Yin, D.S. Dimitrov, J. Gilly, L. Han, H. Jiang, Y. Xie, &amp; J. Zhu, Rapid restoration of potent neutralization activity against the latest Omicron variant JN.1 via AI rational design and antibody engineering, Proc. Natl. Acad. Sci. U.S.A. 122 (6) e2406659122, https:\/\/doi.org\/10.1073\/pnas.2406659122 (2025).<\/p>\n<p>\u30102\u3011Cai, H., Zhang, Z., Wang, M. et al. Pretrainable geometric graph neural network for antibody affinity maturation. 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