{"id":38685,"date":"2025-02-21T02:00:55","date_gmt":"2025-02-20T18:00:55","guid":{"rendered":"https:\/\/17aitech.com\/?p=38685"},"modified":"2025-02-21T02:00:55","modified_gmt":"2025-02-20T18:00:55","slug":"%e9%a2%84%e6%b5%8b%e6%89%80%e6%9c%89%e7%89%a9%e7%a7%8ddna%e3%80%81rna%e3%80%81%e8%9b%8b%e7%99%bd%e8%b4%a8%e7%9a%84%e5%bd%a2%e5%bc%8f%e5%92%8c%e5%8a%9f%e8%83%bd%ef%bc%8carc%e3%80%81%e6%96%af%e5%9d%a6","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=38685","title":{"rendered":"\u9884\u6d4b\u6240\u6709\u7269\u79cdDNA\u3001RNA\u3001\u86cb\u767d\u8d28\u7684\u5f62\u5f0f\u548c\u529f\u80fd\uff0cArc\u3001\u65af\u5766\u798f\u3001NVIDIA\u53d1\u5e03\u6700\u5927AI\u751f\u7269\u6a21\u578bEvo2"},"content":{"rendered":"

\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:\u9884\u6d4b\u6240\u6709\u7269\u79cdDNA\u3001RNA\u3001\u86cb\u767d\u8d28\u7684\u5f62\u5f0f\u548c\u529f\u80fd\uff0cArc\u3001\u65af\u5766\u798f\u3001NVIDIA\u53d1\u5e03\u6700\u5927AI\u751f\u7269\u6a21\u578bEvo2<\/a><\/p>\n

<\/a><\/strong><\/strong><\/strong><\/p>\n

\u7f16\u8f91 | \u841d\u535c\u76ae<\/p>\n

\u6240\u6709\u751f\u547d\u90fd\u7528 DNA \u7f16\u7801\u4fe1\u606f\u3002\u867d\u7136\u6d4b\u5e8f\u3001\u5408\u6210\u548c\u7f16\u8f91\u57fa\u56e0\u7ec4\u4ee3\u7801\u7684\u5de5\u5177\u5df2\u7ecf\u6539\u53d8\u4e86\u751f\u7269\u5b66\u7814\u7a76\uff0c\u4f46\u667a\u80fd\u5730\u7f16\u5199\u65b0\u7684\u751f\u7269\u7cfb\u7edf\u8fd8\u9700\u8981\u6df1\u5165\u4e86\u89e3\u57fa\u56e0\u7ec4\u7f16\u7801\u7684\u5de8\u5927\u590d\u6742\u6027\u3002<\/p>\n

\u79d1\u5b66\u5bb6\u4eec\u4eca\u5929\u53d1\u5e03\u4e86\u4ed6\u4eec\u6240\u79f0\u7684\u6709\u53f2\u4ee5\u6765\u6700\u5927\u7684\u751f\u7269\u5b66\u4eba\u5de5\u667a\u80fd<\/mark>\uff08AI\uff09\u6a21\u578b\u2014\u2014Evo-2\u3002<\/p>\n

\u8be5\u6a21\u578b\u57fa\u4e8e 128,000 \u4e2a\u57fa\u56e0\u7ec4\u8fdb\u884c\u8bad\u7ec3\uff0c\u6db5\u76d6\u4e86\u4ece\u4eba\u7c7b\u5230\u5355\u7ec6\u80de\u7ec6\u83cc\u548c\u53e4\u7ec6\u83cc\u7684\u751f\u547d\u4e4b\u6811\uff0c\u53ef\u4ee5\u4ece\u5934\u5f00\u59cb\u7f16\u5199\u6574\u4e2a\u67d3\u8272\u4f53\u548c\u5c0f\u57fa\u56e0\u7ec4\u3002\u5b83\u8fd8\u53ef\u4ee5\u7406\u89e3\u73b0\u6709\u7684 DNA\uff0c\u5305\u62ec\u4e0e\u75be\u75c5\u76f8\u5173\u7684\u96be\u4ee5\u89e3\u91ca\u7684\u300c\u975e\u7f16\u7801\u300d\u57fa\u56e0\u53d8\u4f53\u3002<\/p>\n

Evo-2 \u7531\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\u5e15\u6d1b\u963f\u5c14\u6258\u7684 Arc \u7814\u7a76\u6240\u548c\u65af\u5766\u798f\u5927\u5b66\u7684\u7814\u7a76\u4eba\u5458\u4ee5\u53ca\u82af\u7247\u5236\u9020\u5546 NVIDIA \u5171\u540c\u5f00\u53d1\uff0c\u79d1\u5b66\u5bb6\u53ef\u4ee5\u901a\u8fc7\u7ebf\u4e0a\u754c\u9762\u4f7f\u7528\uff0c\u4e5f\u53ef\u4ee5\u514d\u8d39\u4e0b\u8f7d\u5176\u8f6f\u4ef6\u4ee3\u7801\u3001\u6570\u636e\u548c\u590d\u5236\u6a21\u578b\u6240\u9700\u7684\u5176\u4ed6\u53c2\u6570<\/mark>\u3002<\/p>\n

\u9879\u76ee\u94fe\u63a5\uff1ahttps:\/\/github.com\/ArcInstitute\/evo2<\/p>\n

\u5f00\u53d1\u4eba\u5458\u5c06 Evo-2 \u89c6\u4e3a\u4e00\u4e2a\u5e73\u53f0\uff0c\u5176\u4ed6\u79d1\u7814\u4eba\u5458\u53ef\u4ee5\u6839\u636e\u81ea\u5df1\u7684\u7528\u9014\u8fdb\u884c\u8c03\u6574\u3002<\/p>\n

\u300c\u6211\u4eec\u975e\u5e38\u671f\u5f85\u79d1\u5b66\u5bb6\u548c\u5de5\u7a0b\u5e08\u5982\u4f55\u4e3a\u751f\u7269\u5b66\u6253\u9020\u8fd9\u4e2a\u300e\u5e94\u7528\u5546\u5e97\u300f\uff0c\u300dArc \u7814\u7a76\u6240\u548c\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u7684\u751f\u7269\u5de5\u7a0b\u5e08 Patrick Hsu \u5728\u5ba3\u5e03 Evo-2 \u53d1\u5e03\u7684\u65b0\u95fb\u53d1\u5e03\u4f1a\u4e0a\u8868\u793a\u3002<\/p>\n

\u8be5\u6a21\u578b\u5728 Arc \u7814\u7a76\u6240\u7f51\u7ad9\u4e0a\u53d1\u5e03\u7684\u4e00\u7bc7\u8bba\u6587\u4e2d\u8fdb\u884c\u4e86\u63cf\u8ff0\uff0c\u5e76\u63d0\u4ea4\u7ed9\u4e86 bioRxiv \u9884\u5370\u672c\u670d\u52a1\u5668\u3002\u4f46\u4ed6\u4eec\u8868\u793a\uff0c\u5728\u5f97\u51fa\u786e\u5207\u7ed3\u8bba\u4e4b\u524d\uff0c\u4ed6\u4eec\u9700\u8981\u591a\u8fdb\u884c\u4e00\u4e9b\u6d4b\u8bd5\u3002<\/p>\n

\u300c\u6211\u4eec\u5fc5\u987b\u5728\u9884\u5370\u672c\u53d1\u5e03\u540e\u770b\u770b\u5b83\u5728\u72ec\u7acb\u57fa\u51c6<\/mark>\u6d4b\u8bd5\u4e2d\u7684\u8868\u73b0\u5982\u4f55\u3002\u300d\u65af\u5766\u798f\u5927\u5b66\u5e15\u6d1b\u963f\u5c14\u6258\u5206\u6821\u7684\u8ba1\u7b97\u57fa\u56e0\u7ec4\u5b66\u5bb6 Anshul Kundaje \u8bf4\u3002<\/p>\n

AWS \u53d1\u63a8\u6587\u79f0 Evo 2 \u4f7f\u7528 AWS \u4e0a\u7684 Nvidia DGX Cloud \u6784\u5efa\uff0c\u73b0\u5728\u662f\u8de8\u7269\u79cd\u5206\u6790 DNA\u3001RNA \u548c\u86cb\u767d\u8d28\u7684\u6700\u5927\u7684\u516c\u5171 AI \u6a21\u578b\u3002<\/p>\n

<\/a><\/section>\n

\u5173\u4e8e Evo-2 \u6a21\u578b<\/strong><\/p>\n

\u5728\u8fc7\u53bb\u7684\u51e0\u5e74\u91cc\uff0c\u7814\u7a76\u4eba\u5458\u5f00\u53d1\u51fa\u4e86\u8d8a\u6765\u8d8a\u5f3a\u5927\u7684\u300c\u86cb\u767d\u8d28\u8bed\u8a00\u6a21\u578b<\/mark>\u300d\uff0c\u4f8b\u5982\u7531 Meta \u524d\u5458\u5de5\u5f00\u53d1\u7684 ESM-3 \u6a21\u578b\uff0c\u8be5\u6a21\u578b\u7ecf\u8fc7\u6570\u767e\u4e07\u4e2a\u86cb\u767d\u8d28\u5e8f\u5217\u7684\u8bad\u7ec3\u540e\uff0c\u5df2\u7528\u4e8e\u5e2e\u52a9\u9884\u6d4b\u86cb\u767d\u8d28\u7ed3\u6784\u548c\u8bbe\u8ba1\u5168\u65b0\u7684\u86cb\u767d\u8d28\uff0c\u5305\u62ec\u57fa\u56e0\u7f16\u8f91\u5668\u548c\u8367\u5149\u5206\u5b50\u3002<\/p>\n

\u4e0e\u8fd9\u4e9b\u6a21\u578b\u4e0d\u540c\u7684\u662f\uff0cEvo-2 \u7684\u8bad\u7ec3\u6240\u7528\u57fa\u56e0\u7ec4\u6570\u636e\u65e2\u5305\u542b\u300c\u7f16\u7801\u5e8f\u5217\u300d\uff08\u643a\u5e26\u5236\u9020\u86cb\u767d\u8d28\u7684\u6307\u4ee4\uff09\uff0c\u4e5f\u5305\u542b\u975e\u7f16\u7801 DNA\uff0c\u540e\u8005\u5305\u62ec\u53ef\u4ee5\u63a7\u5236\u57fa\u56e0\u4f55\u65f6\u3001\u4f55\u5730\u548c\u5982\u4f55\u6d3b\u8dc3\u7684\u5e8f\u5217\u3002<\/p>\n

2024 \u5e74\u53d1\u5e03\u7684 Evo \u7684\u7b2c\u4e00\u4e2a\u7248\u672c\u662f\u5728 80,000 \u79cd\u7ec6\u83cc\u548c\u53e4\u7ec6\u83cc\uff08\u79f0\u4e3a\u539f\u6838\u751f\u7269\u7684\u7b80\u5355\u751f\u7269\uff09\u7684\u57fa\u56e0\u7ec4\u4ee5\u53ca\u5b83\u4eec\u7684\u75c5\u6bd2\u548c\u5176\u4ed6\u5e8f\u5217\u4e0a\u8fdb\u884c\u8bad\u7ec3\u7684\u3002<\/p>\n

\u6700\u65b0\u6a21\u578b\u57fa\u4e8e 128,000 \u4e2a\u57fa\u56e0\u7ec4\uff0c\u5305\u62ec\u4eba\u7c7b\u548c\u5176\u4ed6\u52a8\u7269\u3001\u690d\u7269\u548c\u5176\u4ed6\u771f\u6838\u751f\u7269\u7684\u57fa\u56e0\u7ec4\u3002\u8fd9\u4e9b\u57fa\u56e0\u7ec4\u603b\u5171\u5305\u542b 9.3 \u4e07\u4ebf\u4e2a DNA \u78b1\u57fa\u5bf9\u3002\u6839\u636e\u5904\u7406\u8fd9\u4e9b\u6570\u636e\u548c\u5176\u4ed6\u7279\u5f81\u6240\u9700\u7684\u8ba1\u7b97\u80fd\u529b\uff0cEvo-2 \u662f\u8fc4\u4eca\u4e3a\u6b62\u53d1\u5e03\u7684\u6700\u5927\u7684\u751f\u7269 AI \u6a21\u578b\uff0cHsu \u8bf4\u3002<\/p>\n

\u7814\u7a76\u4eba\u5458\u4f7f\u7528 7B \u548c 40B \u53c2\u6570<\/mark>\u8bad\u7ec3 Evo 2\uff0c\u4ee5\u83b7\u5f97\u524d\u6240\u672a\u6709\u7684 100 \u4e07\u4e2a\u5177\u6709\u5355\u6838\u82f7\u9178\u5206\u8fa8\u7387\u7684\u6807\u8bb0\u4e0a\u4e0b\u6587\u7a97\u53e3\u3002<\/p>\n

Evo 2 \u4ec5\u4ece DNA \u5e8f\u5217\u4e2d\u5b66\u4e60\uff0c\u5373\u53ef\u51c6\u786e\u9884\u6d4b\u9057\u4f20\u53d8\u5f02\u7684\u529f\u80fd\u5f71\u54cd\uff0c\u800c\u65e0\u9700\u9488\u5bf9\u7279\u5b9a\u4efb\u52a1\u8fdb\u884c\u5fae\u8c03\u3002\u901a\u8fc7\u5e94\u7528\u673a\u68b0\u53ef\u89e3\u91ca\u6027\u5206\u6790\uff0c\u56e2\u961f\u53d1\u73b0 Evo 2 \u53ef\u4ee5\u81ea\u4e3b\u5b66\u4e60\u5e7f\u6cdb\u7684\u751f\u7269\u5b66\u7279\u5f81\uff0c\u5305\u62ec\u5916\u663e\u5b50-\u5185\u542b\u5b50\u8fb9\u754c\u3001\u8f6c\u5f55\u56e0\u5b50\u7ed3\u5408\u4f4d\u70b9\u3001\u86cb\u767d\u8d28\u7ed3\u6784\u5143\u7d20\u548c\u566c\u83cc\u4f53\u57fa\u56e0\u7ec4\u533a\u57df\u3002<\/p>\n

\u9664\u4e86\u9884\u6d4b\u80fd\u529b\u4e4b\u5916\uff0cEvo 2 \u8fd8\u80fd\u5728\u57fa\u56e0\u7ec4\u89c4\u6a21\u4e0a\u751f\u6210\u7ebf\u7c92\u4f53\u3001\u539f\u6838\u751f\u7269\u548c\u771f\u6838\u751f\u7269\u5e8f\u5217\uff0c\u5176\u81ea\u7136\u6027\u548c\u8fde\u8d2f\u6027\u6bd4\u4ee5\u524d\u7684\u65b9\u6cd5\u66f4\u9ad8\u3002\u901a\u8fc7\u63a8\u7406\u65f6\u95f4\u641c\u7d22\u5f15\u5bfc Evo 2 \u53ef\u4ee5\u5b9e\u73b0\u53ef\u63a7\u7684\u8868\u89c2\u57fa\u56e0\u7ec4\u7ed3\u6784\u751f\u6210\uff0c\u4e3a\u6b64\u7814\u7a76\u4eba\u5458\u5728\u8bba\u6587\u91cc\u5c55\u793a\u4e86\u751f\u7269\u5b66\u4e2d\u7b2c\u4e00\u4e2a\u63a8\u7406\u65f6\u95f4\u7f29\u653e\u7ed3\u679c\u3002<\/p>\n

<\/a><\/section>\n

\u8bba\u6587\u94fe\u63a5\uff1ahttps:\/\/arcinstitute.org\/manuscripts\/Evo2<\/p>\n

<\/a><\/section>\n

\u56fe\u793a\uff1aEvo 2 \u7684\u6a21\u578b\u67b6\u6784\u3001\u8bad\u7ec3\u7a0b\u5e8f\u3001\u6570\u636e\u96c6\u548c\u8bc4\u4f30\u6982\u8ff0\u3002\uff08\u6765\u6e90\uff1a\u8bba\u6587\uff09<\/p>\n

\u5728\u6a21\u578b\u67b6\u6784\u4e0e\u8bad\u7ec3\u65b9\u9762\uff0c\u7814\u7a76\u4eba\u5458\u63d0\u51fa\u4e86\u5377\u79ef\u591a\u6df7\u5408\u67b6\u6784\uff0c\u5176\u8bbe\u8ba1\u57fa\u4e8e\u4e24\u4e2a\u7b80\u5355\u7684\u89c2\u5bdf\u3002\u9996\u5148\uff0c\u6df7\u5408\u6a21\u578b\u4e2d\u7684\u8fd0\u7b97\u7b26\u53ef\u4ee5\u6839\u636e token \u64cd\u4f5c\u4efb\u52a1\u8fdb\u884c\u5b9a\u5236\uff0c\u4f8b\u5982\u4e0a\u4e0b\u6587\u56de\u5fc6\u3001\u591a token \u56de\u5fc6\u548c\u538b\u7f29\uff0c\u5176\u4e2d\u8f93\u5165\u76f8\u5173\u7684\u5377\u79ef\u548c\u6ce8\u610f\u529b\u673a\u5236<\/mark>\u53ef\u63d0\u4f9b\u4e92\u8865\u7684\u6027\u80fd\u3002<\/p>\n

\u5176\u6b21\uff0c\u5728\u4ee5\u524d\u7684\u66ff\u4ee3\u67b6\u6784\u96be\u4ee5\u8d85\u8d8a Transformers \u7684\u9886\u57df\uff0c\u5171\u540c\u8bbe\u8ba1\u5377\u79ef\u8fd0\u7b97\u7b26\u548c\u786c\u4ef6\u611f\u77e5<\/mark>\u7b97\u6cd5\u53ef\u4ee5\u63d0\u9ad8\u6548\u7387\u3002\u5728 400 \u4ebf\u4e2a\u53c2\u6570<\/mark>\u89c4\u6a21\u4e0b\uff0c\u6211\u4eec\u7684\u7aef\u5230\u7aef\u8bad\u7ec3\u901f\u5ea6\u6bd4\u4f18\u5316\u7684 Transformers \u5feb 1.2 \u5230 2.9 \u500d\uff0c\u6bd4\u4e0a\u4e00\u4ee3\u6df7\u5408\u6a21\u578b\u5feb 1.1 \u5230 1.4 \u500d\u3002<\/p>\n

\u5728 H100 GPU \u548c 4096 \u6a21\u578b\u5bbd\u5ea6\u4e0a\uff0c\u5efa\u8bae\u7684\u591a\u6df7\u5408 StripedHyena 2 \u67b6\u6784\u4e2d\u7684\u5404\u4e2a\u8fd0\u7b97\u7b26\u7684\u541e\u5410\u91cf\u6bd4\u7ebf\u6027\u6ce8\u610f\u548c\u72b6\u6001\u7a7a\u95f4\u6a21\u578b\u63d0\u9ad8\u4e86\u4e24\u500d\u3002\u591a\u6df7\u5408\u5728\u5b57\u8282\u6807\u8bb0\u6570\u636e\u7684\u5e8f\u5217\u5efa\u6a21\u65b9\u9762\u8868\u73b0\u51fa\u8272\uff0c\u6b63\u5982 Evo 2 \u7cfb\u5217\u6a21\u578b\u6240\u8bc1\u660e\u7684\u90a3\u6837\u3002<\/p>\n

<\/a><\/section>\n

\u8bba\u6587\u94fe\u63a5\uff1ahttps:\/\/arcinstitute.org\/manuscripts\/Evo2-ML<\/p>\n

<\/a><\/section>\n
\u56fe\u793a\uff1a\u7ebf\u4e0a\u64cd\u4f5c\u754c\u9762\u3002\uff08\u6765\u6e90\uff1a\u5b98\u7f51\uff09<\/section>\n

\u6240\u6709\u5e8f\u5217\u90fd\u80fd\u751f\u6210<\/strong><\/p>\n

\u4e0e\u539f\u6838\u751f\u7269\u76f8\u6bd4\uff0c\u771f\u6838\u751f\u7269\u7684\u57fa\u56e0\u7ec4\u5f80\u5f80\u66f4\u957f\u3001\u66f4\u590d\u6742\uff1a\u57fa\u56e0\u7531\u6563\u5e03\u7684\u7f16\u7801\u533a\u548c\u975e\u7f16\u7801\u533a\u7247\u6bb5\u7ec4\u6210\uff0c\u975e\u7f16\u7801\u7684\u300c\u8c03\u63a7 DNA\u300d\u53ef\u80fd\u8fdc\u79bb\u5b83\u4eec\u63a7\u5236\u7684\u57fa\u56e0\u3002\u4e3a\u4e86\u5904\u7406\u8fd9\u79cd\u590d\u6742\u6027\uff0cEvo-2 \u7684\u8bbe\u8ba1\u4f7f\u5176\u80fd\u591f\u5b66\u4e60\u8fdc\u81f3 100 \u4e07\u4e2a\u78b1\u57fa\u5bf9\u7684 DNA \u5e8f\u5217\u4e2d\u7684\u6a21\u5f0f\u3002<\/p>\n

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<\/a><\/section>\n

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\u86cb\u767d\u8d28\u8bed\u8a00\u6a21\u578b<\/mark>\u548c\u5176\u4ed6\u7528\u4e8e\u86cb\u767d\u8d28\u8bbe\u8ba1\u7684 AI \u5de5\u5177\u5f15\u53d1\u4e86\u4e00\u573a\u751f\u7269\u8bbe\u8ba1\u9769\u547d\u3002Hie \u56e2\u961f\u6700\u7ec8\u5e0c\u671b\u7528 AI \u6a21\u62df\u6574\u4e2a\u7ec6\u80de\uff0c\u4ed6\u4eec\u5e0c\u671b\u50cf Evo-2 \u8fd9\u6837\u7684\u57fa\u56e0\u7ec4\u6a21\u578b\u80fd\u591f\u8fdb\u4e00\u6b65\u63a8\u52a8\u8fd9\u4e00\u8fdb\u7a0b\u3002<\/p>\n

\u300c\u6211\u4eec\u5e0c\u671b\u5c06\u8be5\u9886\u57df\u4ece\u86cb\u767d\u8d28\u8bbe\u8ba1\u63a8\u5411\u57fa\u56e0\u7ec4\u8bbe\u8ba1\u3002\u300dHie \u8868\u793a\u3002<\/p>\n

<\/a><\/a><\/section>\n

\u89c6\u9891\u94fe\u63a5\uff1ahttps:\/\/mp.weixin.qq.com\/s\/o4ECM6F-dK2PUagS8kSYbg<\/a><\/p>\n

\u76f8\u5173\u62a5\u9053\uff1a<\/p>\n

https:\/\/news.stanford.edu\/stories\/2025\/02\/generative-ai-tool-marks-a-milestone-in-biology-and-accelerates-the-future-of-life-sciences<\/p>\n

https:\/\/arcinstitute.org\/news\/blog\/evo2<\/p>\n

https:\/\/blogs.nvidia.com\/blog\/evo-2-biomolecular-ai\/<\/p>\n

https:\/\/www.nature.com\/articles\/d41586-025-00531-3<\/p>\n

https:\/\/x.com\/awscloud\/status\/1892244930292015336<\/p>\n

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