{"id":39243,"date":"2025-03-06T08:01:47","date_gmt":"2025-03-06T00:01:47","guid":{"rendered":"https:\/\/17aitech.com\/?p=39243"},"modified":"2025-03-06T08:01:47","modified_gmt":"2025-03-06T00:01:47","slug":"%e6%97%a0%e7%bc%9d%e9%9b%86%e6%88%90%e7%9f%a5%e8%af%86%e5%9b%be%e8%b0%b1%ef%bc%8c%e5%bc%80%e6%ba%90python%e6%a1%86%e6%9e%b6biochatter%e9%99%8d%e4%bd%8ellm%e7%94%9f%e7%89%a9%e5%8c%bb%e5%ad%a6%e4%bd%bf","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=39243","title":{"rendered":"\u65e0\u7f1d\u96c6\u6210\u77e5\u8bc6\u56fe\u8c31\uff0c\u5f00\u6e90Python\u6846\u67b6BioChatter\u964d\u4f4eLLM\u751f\u7269\u533b\u5b66\u4f7f\u7528\u95e8\u69db"},"content":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2025-03-05-5\" target=\"_blank\">\u65e0\u7f1d\u96c6\u6210\u77e5\u8bc6\u56fe\u8c31\uff0c\u5f00\u6e90Python\u6846\u67b6BioChatter\u964d\u4f4eLLM\u751f\u7269\u533b\u5b66\u4f7f\u7528\u95e8\u69db<\/a><\/p>\n<p><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-958f8619a7ab4b4b62703b429ee316b8.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-958f8619a7ab4b4b62703b429ee316b8.png\"><\/a><\/p>\n<section>\u7f16\u8f91\u4e28coisini<\/section>\n<section>\u5927\u578b<mark data-type=\"tech_tasks\" data-id=\"bf35ef94-d956-4033-a533-0c0828308c36\">\u8bed\u8a00\u6a21\u578b<\/mark>\uff08LLMs\uff09\u5df2\u7ecf\u6539\u53d8\u4e86\u4eba\u4eec\u7684\u5de5\u4f5c\u65b9\u5f0f\uff0c\u4ece\u652f\u6301\u5185\u5bb9\u521b\u4f5c\u3001\u7f16\u7a0b\u5230\u6539\u8fdb\u641c\u7d22\u5f15\u64ce\u7b49\u3002\u7136\u800c\uff0cLLMs \u5728\u900f\u660e\u5ea6\u3001\u53ef\u91cd\u590d\u6027\u548c\u5b9a\u5236\u5316\u65b9\u9762\u7684\u4e0d\u8db3\u4ecd\u7136\u662f\u4e00\u4e2a\u6311\u6218\uff0c\u9650\u5236\u4e86\u5b83\u4eec\u5728\u751f\u7269\u533b\u5b66\u7814\u7a76\u4e2d\u7684\u5e7f\u6cdb\u5e94\u7528\u3002<\/section>\n<section>\u5bf9\u751f\u7269\u533b\u5b66\u7814\u7a76\u4eba\u5458\u6765\u8bf4\uff0c\u9488\u5bf9\u7279\u5b9a\u7814\u7a76\u95ee\u9898\u4f18\u5316 LLMs \u53ef\u80fd\u662f\u4e00\u9879\u8270\u5de8\u7684\u4efb\u52a1\uff0c\u56e0\u4e3a\u8fd9\u9700\u8981\u7f16\u7a0b\u6280\u80fd\u548c<mark data-type=\"tech_methods\" data-id=\"1a0e9c5e-6502-4cd7-8683-6b5ca6c48be2\">\u673a\u5668\u5b66\u4e60<\/mark>\u4e13\u4e1a\u77e5\u8bc6\u3002\u8fd9\u4e9b\u969c\u788d\u51cf\u5c11\u4e86\u8bb8\u591a\u7814\u7a76\u4efb\u52a1\u4e2d LLMs \u7684\u91c7\u7528\u3002<\/section>\n<section>\u4e3a\u4e86\u514b\u670d\u8fd9\u4e9b\u9650\u5236\uff0c\u6700\u8fd1\u6d77\u5fb7\u5821\u5927\u5b66\u3001\u6b27\u6d32\u751f\u7269\u4fe1\u606f\u7814\u7a76\u6240\uff08EMBL-EBI\uff09\u7b49\u673a\u6784\u53d1\u8868\u5728\u300aNature Biotechnology\u300b\u6742\u5fd7\u4e0a\u7684\u4e00\u9879\u65b0\u7814\u7a76\u63d0\u51fa\u4e86 BioChatter\u3002BioChatter \u65e8\u5728\u901a\u8fc7\u63d0\u4f9b\u4e00\u4e2a\u5f00\u653e\u3001\u900f\u660e\u7684\u5f00\u6e90 Python \u6846\u67b6\uff0c\u6765\u964d\u4f4e\u751f\u7269\u533b\u5b66\u7814\u7a76\u4eba\u5458\u4f7f\u7528 LLMs \u7684\u95e8\u69db\u3002\u8be5\u6846\u67b6\u53ef\u4ee5\u9002\u5e94\u4e0d\u540c\u7684\u7814\u7a76\u9700\u6c42\uff0c\u5c06\u5e2e\u52a9\u79d1\u5b66\u5bb6\u4e13\u6ce8\u4e8e\u4ed6\u4eec\u7684\u7814\u7a76\uff0c\u5c06\u6280\u672f\u590d\u6742\u6027\u4ea4\u7ed9\u5e73\u53f0\u5904\u7406\u3002<\/section>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-dd67877e38d6f401dfa7c66d03d4b594.jpeg\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-dd67877e38d6f401dfa7c66d03d4b594.jpeg\"><\/a><\/section>\n<ul>\n<li>\n<section>\u8bba\u6587\u5730\u5740\uff1a<em>https:\/\/www.nature.com\/articles\/s41587-024-02534-3<\/em><\/section>\n<\/li>\n<li>\n<section>\u9879\u76ee\u5730\u5740\uff1a<em>https:\/\/github.com\/biocypher\/biochatter<\/em><\/section>\n<\/li>\n<\/ul>\n<section><strong>\u4e0e\u751f\u7269\u533b\u5b66<mark data-type=\"tech_methods\" data-id=\"6e896233-3f15-47a4-9b2e-479d7cc5478b\">\u77e5\u8bc6\u56fe\u8c31<\/mark>\u65e0\u7f1d\u96c6\u6210\u7684\u5f00\u6e90\u6846\u67b6<\/strong><\/section>\n<section>BioChatter \u53ef\u4ee5\u9002\u5e94\u7279\u5b9a\u7684\u7814\u7a76\u9886\u57df\uff0c\u4ece\u751f\u7269\u533b\u5b66<mark data-type=\"concepts\" data-id=\"700f9c0f-1e8b-4fde-8bae-6de39c13f022\">\u6570\u636e\u5e93<\/mark>\u548c\u6587\u732e\u4e2d\u63d0\u53d6\u6570\u636e\u3002\u6b64\u5916\uff0c\u901a\u8fc7 BioChatter \u7684 API \u8c03\u7528\u529f\u80fd\uff0c\u6307\u5bfc LLMs \u4f7f\u7528\u5916\u90e8\u8f6f\u4ef6\u53ef\u4ee5\u5b9e\u73b0\u5bf9\u6700\u65b0\u4fe1\u606f\u7684\u5b9e\u65f6\u8bbf\u95ee\uff0c\u5e76\u4e0e\u751f\u7269\u4fe1\u606f\u5b66\u5de5\u5177\u96c6\u6210\u3002<\/section>\n<section>BioChatter \u7684\u4e00\u4e2a\u5173\u952e\u7279\u6027\u662f\u5176\u80fd\u591f\u4e0e BioCypher\uff08\u9762\u5411\u751f\u547d\u79d1\u5b66\u7814\u7a76\u8bbe\u8ba1\u7684<mark data-type=\"tech_methods\" data-id=\"6e896233-3f15-47a4-9b2e-479d7cc5478b\">\u77e5\u8bc6\u56fe\u8c31<\/mark>\u6784\u5efa\u6846\u67b6\uff09\u6784\u5efa\u7684<mark data-type=\"tech_methods\" data-id=\"6e896233-3f15-47a4-9b2e-479d7cc5478b\">\u77e5\u8bc6\u56fe\u8c31<\/mark>\u9ad8\u5ea6\u96c6\u6210 \u2014\u2014 \u8fd9\u4e9b\u56fe\u8c31\u94fe\u63a5\u4e86\u751f\u7269\u533b\u5b66\u6570\u636e\uff0c\u5982\u57fa\u56e0\u7a81\u53d8\u3001\u836f\u7269 &#8211; \u75be\u75c5\u5173\u8054\u548c\u5176\u4ed6\u4e34\u5e8a\u4fe1\u606f\uff0c\u65e8\u5728\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u5206\u6790\u590d\u6742\u7684\u6570\u636e\u96c6\uff0c\u4ee5\u8bc6\u522b\u75be\u75c5\u4e2d\u7684\u57fa\u56e0\u53d8\u5f02\u6216\u7406\u89e3\u836f\u7269\u673a\u5236\u3002<\/section>\n<section>BioChatter \u63d0\u4f9b\u4e86\u4e00\u4e2a\u6613\u4e8e\u4f7f\u7528\u7684\u63a5\u53e3\uff0c\u901a\u8fc7\u76f4\u89c2\u7684 API \u4e0e LLMs \u53ca\u8f85\u52a9\u6280\u672f\u8fdb\u884c\u4ea4\u4e92\uff0c\u5176\u529f\u80fd\u53ef\u4ee5\u96c6\u6210\u5230\u4efb\u610f\u6570\u91cf\u7684\u7528\u6237\u754c\u9762\u4e2d\uff0c\u4f8b\u5982 Web \u5e94\u7528\u7a0b\u5e8f\u3001\u547d\u4ee4\u884c\u754c\u9762\u6216\u00a0Jupyter\u00a0\u7b14\u8bb0\u672c\u3002<\/section>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-823a698760d5fc8d0254a362628cb46f.jpeg\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-823a698760d5fc8d0254a362628cb46f.jpeg\"><\/a><\/section>\n<section><em>\u56fe\u6ce8\uff1aBioChatter \u6846\u67b6\u67b6\u6784\u3002<\/em><\/section>\n<section>BioChatter \u6846\u67b6\u8bbe\u8ba1\u4e3a\u6a21\u5757\u5316\u7ed3\u6784\uff1a\u5176\u4efb\u4f55\u7ec4\u4ef6\u90fd\u53ef\u4ee5\u4e0e\u5176\u4ed6\u5b9e\u73b0\u8fdb\u884c\u4ea4\u6362\u3002BioChatter \u7684\u529f\u80fd\u5305\u62ec\uff1a<\/section>\n<ul>\n<li>\n<section>\u4e0e\u7531\u63d0\u4f9b\u5546\uff08\u5982 OpenAI\uff09\u6258\u7ba1\u7684\u5927\u578b<mark data-type=\"tech_tasks\" data-id=\"bf35ef94-d956-4033-a533-0c0828308c36\">\u8bed\u8a00\u6a21\u578b<\/mark>\uff08LLMs\uff09\u4ee5\u53ca\u672c\u5730\u90e8\u7f72\u7684\u5f00\u6e90\u6a21\u578b\u8fdb\u884c\u57fa\u672c\u7684\u95ee\u7b54\u4ea4\u4e92\u3002<\/section>\n<\/li>\n<li>\n<section>\u53ef\u590d\u73b0\u7684\u63d0\u793a\u5de5\u7a0b\uff08prompt engineering\uff09\uff0c\u4ee5\u5f15\u5bfc LLM \u5b8c\u6210\u7279\u5b9a\u4efb\u52a1\u6216\u884c\u4e3a\u3002<\/section>\n<\/li>\n<li>\n<section><mark data-type=\"tech_methods\" data-id=\"6e896233-3f15-47a4-9b2e-479d7cc5478b\">\u77e5\u8bc6\u56fe\u8c31<\/mark>\uff08KG\uff09<mark data-type=\"concepts\" data-id=\"bf740558-f0f7-41a8-87a0-e695a97563b3\">\u67e5\u8be2<\/mark>\uff0c\u5e76\u81ea\u52a8\u96c6\u6210\u5728 BioCypher \u6846\u67b6\u4e2d\u521b\u5efa\u7684\u4efb\u4f55<mark data-type=\"tech_methods\" data-id=\"6e896233-3f15-47a4-9b2e-479d7cc5478b\">\u77e5\u8bc6\u56fe\u8c31<\/mark>\u3002<\/section>\n<\/li>\n<li>\n<section>\u68c0\u7d22\u589e<mark data-type=\"institutions\" data-id=\"6dcd60d7-34f7-4702-b719-5178a4bc83ef\">\u5f3a\u751f<\/mark>\u6210\uff08RAG\uff09\uff1a\u5229\u7528\u7528\u6237\u63d0\u4f9b\u7684\u6587\u732e\u5411\u91cf<mark data-type=\"concepts\" data-id=\"700f9c0f-1e8b-4fde-8bae-6de39c13f022\">\u6570\u636e\u5e93<\/mark>\u5d4c\u5165\uff0c\u589e<mark data-type=\"institutions\" data-id=\"6dcd60d7-34f7-4702-b719-5178a4bc83ef\">\u5f3a\u751f<\/mark>\u6210\u5185\u5bb9\u7684\u51c6\u786e\u6027\u548c\u76f8\u5173\u6027\u3002 \u00a0<\/section>\n<\/li>\n<li>\n<section>\u6a21\u578b\u94fe\u5f0f\u8c03\u7528\uff1a\u901a\u8fc7\u00a0LangChain\u00a0\u6846\u67b6\uff0c\u5728\u5355\u4e00\u5bf9\u8bdd\u4e2d\u534f\u8c03\u591a\u4e2a LLM \u53ca\u5176\u4ed6\u6a21\u578b\uff0c\u5b9e\u73b0\u590d\u6742\u7684\u4ea4\u4e92\u548c\u4efb\u52a1\u6267\u884c\u3002 \u00a0<\/section>\n<\/li>\n<li>\n<section>LLM \u54cd\u5e94\u7684\u771f\u5b9e\u6027\u6838\u67e5\uff1a\u4f7f\u7528\u7b2c\u4e8c\u4e2a LLM \u5bf9\u7b2c\u4e00\u4e2a LLM \u7684\u54cd\u5e94\u8fdb\u884c\u4e8b\u5b9e\u6838\u67e5\uff0c\u4ee5\u63d0\u9ad8\u4fe1\u606f\u7684\u51c6\u786e\u6027\u3002 \u00a0<\/section>\n<\/li>\n<li>\n<section>LLM\u3001\u63d0\u793a\u53ca\u5176\u4ed6\u7ec4\u4ef6\u7684<mark data-type=\"concepts\" data-id=\"308c3a45-0fee-4ec6-858e-85b15f440fc0\">\u57fa\u51c6<\/mark>\u6d4b\u8bd5\uff1a\u5bf9\u4e0d\u540c\u7684 LLM\u3001\u63d0\u793a\u7b56\u7565\u53ca\u5176\u4ed6\u7ec4\u4ef6\u8fdb\u884c\u6027\u80fd\u8bc4\u4f30\u548c\u6bd4\u8f83\uff0c\u4ee5\u4f18\u5316\u7cfb\u7edf\u8868\u73b0\u3002\u00a0<\/section>\n<\/li>\n<\/ul>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-8803dbc1fb44d58e86515e8a7fd83e80.jpeg\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-8803dbc1fb44d58e86515e8a7fd83e80.jpeg\"><\/a><\/section>\n<section><em>\u56fe\u6ce8\uff1aBioChatter \u53ef\u7ec4\u5408\u5e73\u53f0\u67b6\u6784\uff08\u7b80\u5316\uff09\u3002<\/em><\/section>\n<section><strong>\u5b9e\u9a8c\u8bc4\u4f30<\/strong><\/section>\n<section>\u7531\u4e8e\u751f\u7269\u533b\u5b66\u9886\u57df\u6709\u5176\u7279\u5b9a\u7684\u4efb\u52a1\u548c\u8981\u6c42\uff0c\u7814\u7a76\u56e2\u961f\u521b\u5efa\u4e86\u4e00\u4e2a\u5b9a\u5236\u5316\u7684<mark data-type=\"concepts\" data-id=\"308c3a45-0fee-4ec6-858e-85b15f440fc0\">\u57fa\u51c6<\/mark>\u6d4b\u8bd5\uff0c\u4ee5\u4fbf\u66f4\u7cbe\u786e\u5730\u8bc4\u4f30\u5404\u7ec4\u4ef6\u7684\u6027\u80fd\u3002<\/section>\n<section><mark data-type=\"concepts\" data-id=\"308c3a45-0fee-4ec6-858e-85b15f440fc0\">\u57fa\u51c6<\/mark>\u6d4b\u8bd5\u7ed3\u679c\u4e3b\u8981\u8861\u91cf\u4e86 LLM \u5728\u751f\u7269\u533b\u5b66\u7b49\u9886\u57df\u5e94\u7528\u4e2d\u7684\u5b9e\u7528\u6027\u3002<\/section>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-bc7982c58eb1536f3c98bbbb0ac59e93.jpeg\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/03\/frc-bc7982c58eb1536f3c98bbbb0ac59e93.jpeg\"><\/a><\/section>\n<section><em>\u56fe\u6ce8\uff1a<mark data-type=\"concepts\" data-id=\"308c3a45-0fee-4ec6-858e-85b15f440fc0\">\u57fa\u51c6<\/mark>\u6d4b\u8bd5\u7ed3\u679c\u3002<\/em><\/section>\n<section>\u4e3a\u4e86\u8bc4\u4f30 BioChatter \u529f\u80fd\u7684\u4f18\u52bf\uff0c\u7814\u7a76\u56e2\u961f\u6bd4\u8f83\u4e86\u4f7f\u7528\u548c\u4e0d\u4f7f\u7528 BioChatter \u63d0\u793a\u5f15\u64ce\u8fdb\u884c<mark data-type=\"tech_methods\" data-id=\"6e896233-3f15-47a4-9b2e-479d7cc5478b\">\u77e5\u8bc6\u56fe\u8c31<\/mark>\uff08KG\uff09<mark data-type=\"concepts\" data-id=\"bf740558-f0f7-41a8-87a0-e695a97563b3\">\u67e5\u8be2<\/mark>\u7684\u6a21\u578b\u6027\u80fd\u3002\u5b9e\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u672a\u4f7f\u7528\u63d0\u793a\u5f15\u64ce\u7684\u6a21\u578b\u4ecd\u7136\u53ef\u4ee5\u8bbf\u95ee BioCypher 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