{"id":39617,"date":"2025-03-25T00:02:20","date_gmt":"2025-03-24T16:02:20","guid":{"rendered":"https:\/\/17aitech.com\/?p=39617"},"modified":"2025-03-25T00:02:20","modified_gmt":"2025-03-24T16:02:20","slug":"%e7%a7%91%e5%ad%a6%e5%ae%b6%e4%bb%ac%e6%ad%a3%e5%88%a9%e7%94%a8%e6%9c%ba%e5%99%a8%e5%ad%a6%e4%b9%a0%e4%bb%8e%e6%95%b0%e5%8d%83%e7%a7%8d%e6%97%a7%e8%8d%af%e4%b8%ad%e5%af%bb%e6%89%be%e6%96%b0%e7%9a%84","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=39617","title":{"rendered":"\u79d1\u5b66\u5bb6\u4eec\u6b63\u5229\u7528\u673a\u5668\u5b66\u4e60\u4ece\u6570\u5343\u79cd\u65e7\u836f\u4e2d\u5bfb\u627e\u65b0\u7684\u6cbb\u7597\u65b9\u6cd5"},"content":{"rendered":"

\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:\u79d1\u5b66\u5bb6\u4eec\u6b63\u5229\u7528\u673a\u5668\u5b66\u4e60\u4ece\u6570\u5343\u79cd\u65e7\u836f\u4e2d\u5bfb\u627e\u65b0\u7684\u6cbb\u7597\u65b9\u6cd5<\/a><\/p>\n

<\/a><\/p>\n

\u7f16\u8f91 | \u841d\u535c\u76ae<\/p>\n

\u836f\u7269\u518d\u5229\u7528\uff0c\u5373\u5c06\u5e02\u9762\u4e0a\u73b0\u6709\u836f\u7269\u91cd\u65b0\u5b9a\u4f4d\u7528\u4e8e\u6cbb\u7597\u5176\u4ed6\u75be\u75c5\uff0c\u8fd9\u4e3a\u7f55\u89c1\u75c5\u60a3\u8005\u5e26\u6765\u4e86\u66d9\u5149\u3002<\/p>\n

\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08National Institutes of Health\uff09\u5c06\u7f55\u89c1\u75c5\u5b9a\u4e49\u4e3a\u5728\u7f8e\u56fd\u5f71\u54cd\u5c11\u4e8e 20 \u4e07\u4eba\u7684\u75be\u75c5\u3002\u4f46\u6709\u6570\u5343\u79cd\u7f55\u89c1\u75c5\uff0c\u603b\u5171\u5f71\u54cd\u4e86\u6570\u5343\u4e07\u7f8e\u56fd\u4eba\u548c\u5168\u7403\u6570\u4ebf\u4eba\u3002<\/p>\n

\u7136\u800c\uff0c\u8d85\u8fc7 90% \u7684\u7f55\u89c1\u75c5\u6ca1\u6709\u83b7\u6279\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u5927\u578b\u5236\u836f\u516c\u53f8\u4e5f\u6ca1\u6709\u6295\u5165\u5f88\u591a\u8d44\u6e90\u53bb\u5bfb\u627e\u8fd9\u4e9b\u6cbb\u7597\u65b9\u6cd5\u3002NCATS \u836f\u7269\u5f00\u53d1\u5408\u4f5c\u9879\u76ee\u8d1f\u8d23\u4eba Christine Colvis \u8868\u793a\uff0c\u5f00\u53d1\u4e00\u79cd\u9488\u5bf9\u5c11\u91cf\u60a3\u8005\u7684\u65b0\u578b\u836f\u7269\u901a\u5e38\u4e0d\u4f1a\u5e26\u6765\u5f88\u5927\u7684\u7ecf\u6d4e\u6536\u76ca\u3002<\/p>\n

\u901a\u8fc7\u673a\u5668\u5b66\u4e60\uff0c\u79d1\u5b66\u5bb6\u80fd\u591f\u5feb\u901f\u7b5b\u9009\u73b0\u6709\u836f\u7269\uff0c\u5bfb\u627e\u5176\u5bf9\u7f55\u89c1\u75c5\u7684\u6f5c\u5728\u7597\u6548\u3002\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u7684\u533b\u5b66\u526f\u6559\u6388 David Fajgenbaum \u662f\u8fd9\u4e00\u9886\u57df\u7684\u5148\u9a71\u4e4b\u4e00\u3002<\/p>\n

2010 \u5e74\uff0cFajgenbaum \u8fd8\u662f\u4e00\u540d\u533b\u5b66\u751f\uff0c\u5f53\u65f6\u4ed6\u56e0\u7f55\u89c1\u7684 Castleman \u75c5 (CD) \u75c5\u60c5\u5371\u6025\uff0c\u6709\u4e94\u6b21\u9669\u4e9b\u4e27\u547d\u3002\u533b\u751f\u544a\u8bc9 David\uff0c\u4ed6\u7684\u75be\u75c5\u5df2\u7ecf\u6ca1\u6709\u5176\u4ed6\u6cbb\u7597\u9009\u62e9\uff0c\u9664\u975e\u6709\u65b0\u7684\u6cbb\u7597\u65b9\u6cd5\u51fa\u73b0\u3002\u4f46\u662f\uff0c\u5f00\u53d1\u65b0\u7597\u6cd5\u9700\u8981\u6570\u5341\u4ebf\u7f8e\u5143\u7684\u7814\u7a76\u8d44\u91d1\u548c 10-15 \u5e74\u7684\u65f6\u95f4\u3002<\/p>\n

\u5e78\u8fd0\u7684\u662f\uff0cFajgenbaum \u56e2\u961f\u53d1\u73b0\u4e86\u8840\u6db2\u4e2d\u4e00\u6761\u8fc7\u5ea6\u6d3b\u8dc3\u7684\u4fe1\u53f7\u901a\u8def\uff0c\u5e76\u6d4b\u8bd5\u4e86\u4e00\u79cd\u5df2\u6709 25 \u5e74\u5386\u53f2\u7684\u836f\u7269\u897f\u7f57\u83ab\u53f8\uff08sirolimus\uff0c\u53c8\u79f0\u96f7\u5e15\u9709\u7d20\uff09\uff0c\u8be5\u836f\u7269\u88ab\u6279\u51c6\u7528\u4f5c\u80be\u79fb\u690d\u540e\u7684\u514d\u75ab\u6291\u5236\u5242\uff0c\u4f46\u4ece\u672a\u7528\u4e8e\u6cbb\u7597 CD\u3002\u901a\u8fc7\u8be5\u836f\u7269\uff0cFajgenbaum \u7684\u75c5\u60c5\u5df2\u7ecf\u7f13\u89e3\u4e86 11 \u5e74\u3002<\/p>\n

<\/a><\/p>\n

\u8fd9\u4e00\u7ecf\u5386\u4fc3\u4f7f\u4ed6\u81f4\u529b\u4e8e\u836f\u7269\u518d\u5229\u7528\u7814\u7a76\uff0c\u5e76\u6210\u7acb\u4e86\u975e\u8425\u5229\u7ec4\u7ec7 Every Cure\u3002\u5728\u8fc7\u53bb\u7684 10 \u5e74\u91cc\uff0cFajgenbaum \u56e2\u961f\u5df2\u7ecf\u7814\u53d1\u51fa 14 \u79cd\u9488\u5bf9\u591a\u79cd\u75be\u75c5\u7684\u518d\u5229\u7528\u836f\u7269\uff0c\u4ed6\u4eec\u6b63\u5728\u901a\u8fc7 Every Cure \u6269\u5927\u8fd9\u9879\u5de5\u4f5c\u7684\u5f71\u54cd\u3002<\/p>\n

Every Cure \u5b98\u7f51\uff1ahttps:\/\/everycure.org\/<\/p>\n

Every Cure \u6210\u7acb\u7684\u76ee\u7684\u662f\u786e\u4fdd\u60a3\u8005\u4e0d\u4f1a\u56e0\u4e3a\u6f5c\u5728\u6cbb\u7597\u65b9\u6cd5\u88ab\u5ffd\u89c6\u800c\u906d\u53d7\u75db\u82e6\u3002\u8fd9\u662f\u4eba\u5de5\u667a\u80fd\u9996\u6b21\u80fd\u591f\u8de8\u8d8a\u518d\u5229\u7528\u969c\u788d\uff0c\u4ee5\u6781\u4f4e\u7684\u6210\u672c\u548c\u65f6\u95f4\u627e\u5230\u6cbb\u7597\u65b9\u6848\u3002\u4ed6\u4eec\u7684\u4eba\u5de5\u667a\u80fd\u65b9\u6cd5\u53ef\u4ee5\u5feb\u901f\u3001\u7cfb\u7edf\u5730\u5206\u6790\u5168\u7403\u7684\u751f\u7269\u533b\u5b66\u77e5\u8bc6\u3002<\/p>\n

\u4f20\u7edf\u7814\u7a76\u9700\u8981\u6570\u5e74\u65f6\u95f4\u624d\u80fd\u8c03\u67e5\u5b8c\u6240\u6709\u75be\u75c5\uff0c\u800c Fajgenbaum \u7684\u65b9\u6cd5\u6db5\u76d6\u4e86\u6240\u6709 18,000 \u79cd\u75be\u75c5\u548c 4,000 \u79cd\u836f\u7269\uff0c\u53ef\u5728\u51e0\u5929\u5185\u91cf\u5316 7,500 \u4e07\u79cd\u836f\u7269\u4e0e\u75be\u75c5\u7684\u5339\u914d\u7a0b\u5ea6\u3002<\/p>\n

\u836f\u7269\u518d\u5229\u7528\u7684\u4f8b\u5b50\u6709\u5f88\u591a\u3002\u963f\u53f8\u5339\u6797\u6700\u521d\u53ea\u662f\u5f53\u4f5c\u4e00\u79cd\u6b62\u75db\u836f\u548c\u6d88\u708e\u836f\uff0c\u540e\u6765\u53d1\u73b0\u5b83\u8fd8\u5177\u6709\u8840\u6db2\u7a00\u91ca\u7279\u6027\uff0c\u73b0\u5728\u88ab\u5e7f\u6cdb\u7528\u4e8e\u964d\u4f4e\u9ad8\u5371\u4eba\u7fa4\u7684\u5fc3\u810f\u75c5\u53d1\u4f5c\u548c\u4e2d\u98ce\u98ce\u9669\u3002Ozempic\u00a0\u6700\u521d\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597 2 \u578b\u7cd6\u5c3f\u75c5\uff0c\u73b0\u5df2\u88ab\u91cd\u65b0\u7528\u4f5c\u51cf\u80a5\u836f\u3002<\/p>\n

\u8bb8\u591a\u79d1\u5b66\u56e2\u961f\u90fd\u5728\u79ef\u6781\u63a2\u7d22\u836f\u7269\u518d\u5229\u7528\u3002\u6d59\u6c5f\u5927\u5b66\u3001\u4e4b\u6c5f\u5b9e\u9a8c\u5ba4\u63d0\u51fa\u8fc7\u4e00\u79cd\u901a\u8fc7\u5206\u6790\u7ebf\u7c92\u4f53\u8868\u578b\u53d8\u5316\u6765\u8bc6\u522b MOA \u7684\u65b9\u6cd5\uff0c\u540c\u65f6\u5f00\u53d1\u4e86\u6df1\u5ea6\u5b66\u4e60\u6a21\u578b MitoReID\uff0c\u53ef\u4ee5\u52a0\u901f\u5927\u89c4\u6a21\u836f\u7269\u53d1\u73b0\u548c\u518d\u5229\u7528\u3002\u4e2d\u5357\u5927\u5b66\u7684\u7814\u7a76\u4eba\u5458\u63d0\u51fa\u4e86\u4e00\u79cd\u79f0\u4e3a AdaDR \u7684\u81ea\u9002\u5e94 GCN \u65b9\u6cd5\uff0c\u901a\u8fc7\u6df1\u5ea6\u96c6\u6210\u8282\u70b9\u7279\u5f81\u548c\u62d3\u6251\u7ed3\u6784\u6765\u8fdb\u884c\u836f\u7269\u91cd\u65b0\u5b9a\u4f4d\u3002<\/p>\n

\u90d1\u5dde\u5927\u5b66\u3001\u7535\u5b50\u79d1\u6280\u5927\u5b66\u56e2\u961f\u63d0\u51fa\u7684 MIDTI \u65b9\u6cd5\uff0c\u6c5f\u5357\u5927\u5b66\u56e2\u961f\u63d0\u51fa\u7684 MINDG \u65b9\u6cd5\uff0c\u54c8\u5c14\u6ee8\u5de5\u4e1a\u5927\u5b66\u56e2\u961f\u7684 DrugMGR\uff0c\u5747\u501f\u52a9 AI \u6280\u672f\u63d0\u9ad8\u4e86\u836f\u7269-\u9776\u70b9\u76f8\u4e92\u4f5c\u7528\uff08DTI\uff09\u9884\u6d4b\u7684\u51c6\u786e\u6027\uff0c\u6781\u5927\u52a9\u529b\u4e86\u836f\u7269\u518d\u5229\u7528\u7814\u7a76\u3002<\/p>\n

2025 \u5e74 2 \u6708 Google \u63a8\u51fa\u7684\u591a\u667a\u80fd\u4f53\u7cfb\u7edf AI co-scientist\uff0c\u5728\u836f\u7269\u518d\u5229\u7528\u9886\u57df\u540c\u6837\u8868\u73b0\u4f18\u5f02\u3002AI co-scientist \u6210\u529f\u63d0\u51fa\u4e86\u6025\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u7684\u65b0\u578b\u518d\u5229\u7528\u5019\u9009\u836f\u7269\uff0c\u4e14\u5b9e\u9a8c\u8bc1\u5b9e\u5b83\u6240\u5efa\u8bae\u836f\u7269\u5728\u4e34\u5e8a\u76f8\u5173\u6d53\u5ea6\u4e0b\u6291\u5236\u4e86\u80bf\u7624\u6d3b\u529b\u3002<\/p>\n

\u4ee5\u524d\uff0c\u836f\u7269\u518d\u5229\u7528\u53d1\u73b0\u53ea\u662f\u610f\u5916\u60ca\u559c\u3002\u4f46\u73b0\u5728\uff0cAI \u6b63\u9010\u6e10\u4f7f\u8fd9\u4e9b\u53d1\u73b0\u66f4\u6709\u9488\u5bf9\u6027\u548c\u786e\u5b9a\u6027\u3002\u4eba\u5de5\u667a\u80fd\u80fd\u591f\u5206\u6790\u73b0\u6709\u836f\u7269\uff0c\u770b\u770b\u5b83\u4eec\u662f\u5426\u53ef\u7528\u4e8e\u65b0\u7597\u6cd5\u3002<\/p>\n

\u901a\u8fc7\u5206\u6790\u751f\u7269\u9014\u5f84\u548c\u75be\u75c5\u8fdb\u5c55\uff0c\u4eba\u5de5\u667a\u80fd\u53ef\u4ee5\u5c06\u5df2\u6279\u51c6\u7684\u836f\u7269\u4e0e\u65b0\u51fa\u73b0\u7684\u5065\u5eb7\u5a01\u80c1\u76f8\u5339\u914d\u3002\u8fd9\u79cd\u4eba\u5de5\u667a\u80fd\u589e\u5f3a\u65b9\u6cd5\u6709\u52a9\u4e8e\u964d\u4f4e\u5f00\u53d1\u98ce\u9669\uff0c\u627e\u5230\u539f\u672c\u53ef\u80fd\u672a\u53d1\u73b0\u7684\u6a21\u5f0f\uff0c\u5e76\u8ba9\u6cbb\u7597\u66f4\u5feb\u5730\u60e0\u53ca\u60a3\u8005\u3002<\/p>\n

\u54c8\u4f5b\u533b\u5b66\u9662\u526f\u6559\u6388 Marinka Zitnik \u8868\u793a\uff0c\u836f\u7269\u518d\u5b9a\u4f4d\u662f\u5bfb\u627e\u7f55\u89c1\u75c5\u6cbb\u7597\u975e\u5e38\u300c\u8bf1\u4eba\u7684\u66ff\u4ee3\u9014\u5f84\u300d\uff0c\u5979\u7684\u5b9e\u9a8c\u5ba4\u4e5f\u6784\u5efa\u4e86\u4e00\u4e2a\u7528\u4e8e\u836f\u7269\u518d\u5b9a\u4f4d\u7684\u4eba\u5de5\u667a\u80fd\u6a21\u578b\u3002<\/p>\n

<\/a><\/p>\n

\u4e00\u5e74\u524d\uff0cFajgenbaum \u7684\u6280\u672f\u62ef\u6551\u4e86\u4e00\u540d\u56e0\u7f55\u89c1\u7684 POEMS \u7efc\u5408\u75c7\u6fd2\u4e34\u6b7b\u4ea1\u7684\u60a3\u8005\uff0c\u4ed6\u53eb Joseph Coates\u3002\u9762\u5bf9\u4f20\u7edf\u6cbb\u7597\u65b9\u6cd5\u65e0\u529b\u56de\u5929\u7684\u60c5\u5f62\uff0cCoates \u66fe\u8868\u793a\u5df2\u7ecf\u653e\u5f03\u51c6\u5907\u7b49\u5f85\u6b7b\u4ea1\u7684\u5230\u6765\u3002<\/p>\n

\u5e78\u8fd0\u7684\u662f\uff0c\u901a\u8fc7\u4eba\u5de5\u667a\u80fd\u6a21\u578b\u63a8\u8350\u7684\u975e\u4f20\u7edf\u836f\u7269\u7ec4\u5408\uff0c\u4ed6\u5728\u77ed\u65f6\u95f4\u5185\u5bf9\u6cbb\u7597\u4ea7\u751f\u53cd\u5e94\uff0c\u5e76\u6700\u7ec8\u63a5\u53d7\u4e86\u5e72\u7ec6\u80de\u79fb\u690d\uff0c\u6210\u529f\u8fdb\u5165\u7f13\u89e3\u671f\u3002<\/p>\n

Coates \u7684\u6210\u529f\u6cbb\u7597\u4e0d\u4ec5\u5c55\u793a\u4e86\u836f\u7269\u518d\u5229\u7528\u7684\u6f5c\u529b\uff0c\u4e5f\u4f53\u73b0\u4e86\u4eba\u5de5\u667a\u80fd\u5728\u533b\u5b66\u9886\u57df\u7684\u9769\u547d\u6027\u5f71\u54cd\u3002\u901a\u8fc7\u4e0d\u61c8\u52aa\u529b\u548c\u521b\u65b0\u601d\u7ef4\uff0c\u5373\u4f7f\u9762\u5bf9\u6700\u4e25\u5cfb\u7684\u533b\u7597\u6311\u6218\uff0c\u4e5f\u80fd\u627e\u5230\u5e0c\u671b\u7684\u66d9\u5149\u3002<\/p>\n

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