{"id":39878,"date":"2025-04-04T01:02:20","date_gmt":"2025-04-03T17:02:20","guid":{"rendered":"https:\/\/17aitech.com\/?p=39878"},"modified":"2025-04-04T01:02:20","modified_gmt":"2025-04-03T17:02:20","slug":"53%e6%80%a7%e8%83%bd%e5%85%a8%e9%9d%a2%e6%8f%90%e5%8d%87%ef%bc%8cayu%e6%96%b0%e6%a8%a1%e5%9e%8b%e6%a8%aa%e6%89%ab%e4%bc%a0%e7%bb%9f%e5%b7%a5%e5%85%b7%ef%bc%8c%e5%88%86%e6%b3%8c%e8%9b%8b%e7%99%bd","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=39878","title":{"rendered":"53%\u6027\u80fd\u5168\u9762\u63d0\u5347\uff0cAyu\u65b0\u6a21\u578b\u6a2a\u626b\u4f20\u7edf\u5de5\u5177\uff0c\u5206\u6ccc\u86cb\u767d\u9884\u6d4b\u6548\u7387\u518d\u7ffb\u500d"},"content":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2025-04-03-7\" target=\"_blank\">53%\u6027\u80fd\u5168\u9762\u63d0\u5347\uff0cAyu\u65b0\u6a21\u578b\u6a2a\u626b\u4f20\u7edf\u5de5\u5177\uff0c\u5206\u6ccc\u86cb\u767d\u9884\u6d4b\u6548\u7387\u518d\u7ffb\u500d<\/a><\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-5eaf8bff1036d7dc717534104f2d6363.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-5eaf8bff1036d7dc717534104f2d6363.png\"><\/a><\/section>\n<p data-pm-slice=\"0 0 []\">\u7f16\u8f91\u4e28&amp;<\/p>\n<p>\u5fae\u751f\u7269\u662f\u9a71\u52a8\u5143\u7d20\u5faa\u73af\u7684\u5f15\u64ce\uff0c\u5b83\u4eec\u5206\u6ccc\u86cb\u767d\u8d28\u4ee5\u5bfb\u6c42\u751f\u6d3b\u73af\u5883\u3002\u73b0\u9636\u6bb5\u8fd8\u7f3a\u4e4f\u6709\u6548\u7684\u8ba1\u7b97\u65b9\u6cd5\u6765\u7814\u7a76\u5206\u6ccc\u86cb\u767d\u3002\u8868\u5f81\u5206\u6ccc\u7ec4\u7684\u53e6\u4e00\u79cd\u65b9\u6cd5\u662f\u5c06\u73b0\u4ee3\u673a\u5668\u5b66\u4e60\u5de5\u5177\u4e0e\u86cb\u767d\u8d28\u7ec4\u5bf9\u6d77\u6d0b\u73af\u5883\u7684\u8fdb\u5316\u9002\u5e94\u53d8\u5316\u76f8\u7ed3\u5408\u3002<\/p>\n<p>\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u7ef4\u4e5f\u7eb3\u5927\u5b66\uff08<span data-pm-slice=\"0 0 []\">University of Vienna<\/span>\uff09\u4e0e\u4e0a\u6d77\u6d77\u6d0b\u5927\u5b66\u7684\u7814\u7a76\u8005\u8bc6\u522b\u5e76\u63cf\u8ff0\u4e86\u6d77\u6d0b\u7ec6\u80de\u5916\u86cb\u767d\u7684\u9002\u5e94\u6027\uff0c\u5f00\u53d1\u4e86\u4e00\u6b3e\u540d\u4e3a\u300cAyu\u300d\u7684\u673a\u5668\u9884\u6d4b\u5de5\u5177\uff0c\u4e0d\u4f7f\u7528\u57fa\u4e8e\u540c\u6e90\u7684\u9884\u6d4b\u5668\uff0c\u5e76\u4e14\u6bd4\u5f53\u524d\u6700\u5148\u8fdb\u7684\u8f6f\u4ef6\u5b9e\u73b0\u4e86\u66f4\u597d\u3001\u66f4\u5feb\u7684\u6027\u80fd\u3002<\/p>\n<p>\u8be5\u6a21\u578b\u5b9e\u9645\u5e94\u7528\u4e8e\u6d77\u6d0b\u6837\u672c\uff08Tara Oceans \u6570\u636e\u96c6\uff09\u65f6\uff0c\u76f8\u6bd4\u4e8e\u6700\u5e7f\u6cdb\u4f7f\u7528\u7684\u9274\u5b9a\u5206\u6ccc\u86cb\u767d\u7684\u65b9\u6cd5\uff0c\u5168\u65b0\u7684\u65b9\u6cd5\u80fd\u591f\u56de\u6536\u4e24\u500d\u4ee5\u4e0a\u7684\u86cb\u767d\u8d28\u3002<\/p>\n<p>\u4ed6\u4eec\u7684\u7814\u7a76\u6210\u679c\u4ee5\u300cAyu: a machine intelligence tool for identification of extracellular proteins in the marine secretome\u300d\u4e3a\u9898\uff0c\u4e8e 2025 \u5e74 3 \u6708 21 \u65e5\u520a\u767b\u4e8e\u300aNature Communications\u300b\u3002<\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-e5d5f29343fa74fced4d2576eaa678c3.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-e5d5f29343fa74fced4d2576eaa678c3.png\"><\/a><\/section>\n<p><strong>\u5fae\u751f\u7269\u5206\u6ccc\u7814\u7a76<\/strong><\/p>\n<p>\u636e\u5b9e\u9a8c\u5ba4\u7814\u7a76\uff0c\u9ad8\u8fbe 30% \u7684\u7ec6\u83cc\u57fa\u56e0\u7ec4\u7f16\u7801\u91ca\u653e\u5230\u7ec6\u80de\u5916\u73af\u5883\u4e2d\u7684\u86cb\u767d\u8d28\uff0c\u53c2\u4e0e\u5230\u4e86\u7ec6\u83cc\u4e0e\u73af\u5883\u7684\u76f8\u4e92\u4f5c\u7528\u4e2d\u3002\u5bf9\u6d77\u6d0b\u4e2d\u7ec6\u80de\u5916\u9176\u6d3b\u6027\u7684\u6d4b\u91cf\u8868\u660e\uff0c\u8fd9\u4e9b\u53cd\u5e94\u4e3b\u8981\u7531\u6eb6\u89e3\u7684\uff08\u65e0\u7ec6\u80de\u7684\uff09\u9176\u50ac\u5316\uff0c\u6bd4\u7387\u968f\u7740\u6df1\u5ea6\u7684\u589e\u52a0\u800c\u589e\u52a0\u3002<\/p>\n<p>\u5c3d\u7ba1\u5206\u6ccc\u7ec4\u5177\u6709\u76f8\u5173\u6027\uff0c\u4f46\u5176\u7814\u7a76\u56e0\u7f3a\u4e4f\u9002\u5f53\u7684\u65b9\u6cd5\u800c\u53d7\u5230\u9650\u5236\u3002\u4e00\u79cd\u5408\u7406\u7684\u65b9\u6cd5\u662f\u5229\u7528\u5927\u91cf\u53ef\u7528\u7684\u5b8f\u57fa\u56e0\u7ec4\u548c\u5b8f\u8f6c\u5f55\u7ec4\u6570\u636e\u96c6\uff0c\u4f46\u76ee\u524d\u8fd8\u9762\u4e34\u7740\u4ece\u6c28\u57fa\u9178\u5e8f\u5217\u9884\u6d4b\u4e9a\u7ec6\u80de\u5b9a\u4f4d\u7684\u6311\u6218\u3002<\/p>\n<p>\u6d77\u6d0b\u73af\u5883\u7684\u7279\u6b8a\u6027\u4e3a\u6539\u8fdb\u86cb\u767d\u8d28\u5b9a\u4f4d\u9884\u6d4b\u63d0\u4f9b\u4e86\u673a\u4f1a\u3002\u4f17\u6240\u5468\u77e5\uff0c\u86cb\u767d\u8d28\u7684\u6c28\u57fa\u9178\u7ec4\u6210\uff08AAC\uff09\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u9002\u5e94\u4e8e\u5176\u4f4d\u7f6e\u7684\u7269\u7406\u5316\u5b66\u6027\u8d28\u3002\u5bf9\u4e8e\u5728\u5468\u8d28\u4e2d\u8d77\u4f5c\u7528\u7684\u86cb\u767d\u8d28\u6765\u8bf4\uff0c\u5176\u4e0d\u53d7\u6e17\u900f\u538b\u8c03\u8282\u3002<\/p>\n<p>\u56e0\u6b64\uff0c\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u300cAyu\u300d\u6a21\u578b\u88ab\u5f00\u53d1\uff0c\u7528\u4ee5\u5229\u7528\u8fd9\u4e9b\u9002\u5e94\u7559\u4e0b\u7684\u4fe1\u53f7\u6765\u9884\u6d4b\u5927\u578b\u6d77\u6d0b\u5b8f\u57fa\u56e0\u7ec4\u6570\u636e\u96c6\u4e2d\u7684\u5206\u6ccc\u86cb\u767d\uff0c\u5c06\u5176\u6027\u80fd\u4e0e\u6700\u5148\u8fdb\u7684\u4e9a\u7ec6\u80de\u4f4d\u7f6e\u9884\u6d4b\u5de5\u5177\u8fdb\u884c\u6bd4\u8f83\uff0c\u4ee5\u63ed\u793a\u5b9e\u9645\u6d77\u6d0b\u5206\u6ccc\u7ec4\u7684\u542b\u91cf\u548c\u86cb\u767d\u8d28\u7ec4\u6210\u3002<\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-0d1d40a716f08a435a19d703b97b660e.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-0d1d40a716f08a435a19d703b97b660e.png\"><\/a><\/section>\n<p>\u56fe 1\uff1a\u57fa\u4e8e\u6816\u606f\u5730\u7684\u6c28\u57fa\u9178\u7ec4\u6210\u548c pI \u7684\u5dee\u5f02\u3002\uff08\u56fe\u6e90\uff1a\u8bba\u6587\uff09<\/p>\n<p>\u603b\u4f53\u800c\u8a00\uff0c\u7ed3\u679c\u8bc1\u660e\u6d77\u6d0b\u73af\u5883\u5bf9\u66b4\u9732\u4e8e\u5176\u4e2d\u7684\u86cb\u767d\u8d28\u6709\u7279\u5b9a\u5f71\u54cd\uff0c\u76d0\u5ea6\u662f\u660e\u663e\u7684\u7f6a\u9b41\u7978\u9996\u3002<\/p>\n<p>\u4e3a\u4e86\u89e3\u91ca\u5404\u95e8 AAC \u7684\u8fd9\u4e9b\u5dee\u5f02\uff0c\u53ef\u4ee5\u8f6c\u5411\u6240\u793a\u5206\u7c7b\u7fa4\u4e4b\u95f4\u751f\u6d3b\u65b9\u5f0f\u7684\u5dee\u5f02\u3002\u4ee5\u524d\u7684\u7814\u7a76\u63a8\u6d4b\uff0c\u7ec6\u83cc\u4ea7\u751f\u7684\u7ec6\u80de\u5916\u86cb\u767d\u5e73\u5747\u6bd4\u80de\u8d28\u86cb\u767d\u5ec9\u4ef7\uff0c\u56e0\u4e3a\u8fd9\u4e9b\u86cb\u767d\u8d28\u4e0d\u80fd\u56de\u6536\u3002<\/p>\n<p>\u5728\u8fd9\u79cd\u7814\u7a76\u73af\u5883\u4e2d\uff0c\u56e2\u961f\u53d1\u73b0\uff0c\u7ec6\u80de\u5916\u86cb\u767d\u7684\u6210\u672c\u5728\u95e8\u4e4b\u95f4\u5dee\u5f02\u5f88\u5927\u3002\u4ed6\u4eec\u8ba4\u4e3a\u5dee\u5f02\u6e90\u4e8e\u4ea7\u751f\u7ec6\u83cc\u7684\u4e0d\u540c\u8425\u517b\u7b56\u7565\u3002<\/p>\n<p><strong>\u673a\u5668\u5b66\u4e60\u6a21\u578b\u8bbe\u8ba1\u548c\u9a8c\u8bc1<\/strong><\/p>\n<p>\u4f7f\u7528\u4e00\u7ec4\u7ecf\u8fc7\u9a8c\u8bc1\u7684\u86cb\u767d\u8d28\u63cf\u8ff0\u7b26\uff0c\u56e2\u961f\u6d4b\u8bd5\u4e86\u8fd9\u4e9b\u4fe1\u606f\u662f\u5426\u53ef\u7528\u4e8e\u6539\u8fdb\u5f53\u524d\u7684\u4e9a\u7ec6\u80de\u4f4d\u7f6e\u9884\u6d4b\u65b9\u6cd5\u3002\u4ed6\u4eec\u9009\u62e9\u4e86 xgBoost\uff0c\u4ee5\u6b64\u53d1\u6325\u5b83\u9002\u7528\u4e8e\u975e\u53c2\u6570\u6570\u636e\u4e8e\u652f\u6301\u591a\u5206\u7c7b\u7b49\u4f18\u70b9\u3002<\/p>\n<p>\u5206\u6790\u63ed\u793a\u4e86\u7ec6\u80de\u5916&gt;\u5468\u8d28&gt;\u7ec6\u80de\u8d28\u987a\u5e8f\u7684\u9002\u5e94\u68af\u5ea6\uff0c\u73b0\u5728\u56e2\u961f\u901a\u8fc7\u5c06\u95ee\u9898\u6846\u5b9a\u4e3a\u987a\u5e8f\u5206\u7c7b\u6765\u6539\u5584\u9884\u6d4b\uff0c\u5e76\u5206\u5316\u51fa\u4e24\u79cd\u7b56\u7565\uff1a\u591a\u7c7b\u5206\u7c7b\u5668\uff0c\u5c06\u6bcf\u4e2a\u4e9a\u7ec6\u80de\u4f4d\u7f6e\u89c6\u4e3a\u4e00\u4e2a\u72ec\u7acb\u7684\u7c7b\uff0c\u4ee5\u53ca\u5e8f\u6570\u5206\u7c7b\u5668\uff0c\u63a2\u7a76\u7c7b\u4e4b\u95f4\u7684\u5185\u5728\u987a\u5e8f\u3002<\/p>\n<p>\u4e00\u822c\u6765\u8bf4\uff0c\u5728\u6bd4\u8f83 MCC \u548c Kappa \u5206\u6570\u65f6\uff0c\u4e0e pSORTb3 \u548c BUSC \u76f8\u6bd4\uff0c\u6240\u6709 Ayu \u5b9e\u73b0\uff08MCC &gt; 0.89\uff0cKapp&gt;a = 0.89\uff09\u90fd\u660e\u663e\u4f18\u4e8e pSORTb3\uff08MCC = 0.64\uff0cKappa = 0.64\uff09\u3002<\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-8b7f7a41966dfa7012617ec2f3d660bf.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-8b7f7a41966dfa7012617ec2f3d660bf.png\"><\/a><\/section>\n<p>\u56fe 2\uff1aAyu \u4e0e\u5176\u4ed6\u5206\u7c7b\u5668\u7684\u6027\u80fd\u6bd4\u8f83\u3002\uff08\u56fe\u6e90\uff1a\u8bba\u6587\uff09<\/p>\n<p>Ayu \u7684\u4e24\u4e2a\u7248\u672c\uff08\u591a\u7c7b\u548c\u5e8f\u6570\uff09\u90fd\u6bd4\u5176\u4ed6\u5206\u7c7b\u5668\u6709\u6240\u6539\u8fdb\uff0c\u800c\u5e94\u7528 SMOTE \u7b97\u6cd5\u6765\u6539\u5584\u86cb\u767d\u8d28\u7c7b\u522b\u4e4b\u95f4\u7684\u4e0d\u5e73\u8861\u4e5f\u5bf9 Ayu \u7684\u591a\u7c7b\u5b9e\u73b0\u4ea7\u751f\u4e86\u79ef\u6781\u5f71\u54cd\u3002<\/p>\n<p>\u56e2\u961f\u5728\u8bad\u7ec3\u65f6\u95f4\u4e0e\u9884\u6d4b\u65f6\u95f4\u8fdb\u884c\u6743\u8861\uff0c\u6700\u7ec8\u591a\u7c7b\u5b9e\u73b0\u7684 SMOTE \u7248\u672c\u88ab\u4fdd\u7559\u4e3a Ayu \u7684\u6700\u7ec8\u7248\u672c\u3002<\/p>\n<p>\u7531\u4e8e xgBoost \u5c5e\u4e8e\u63d0\u5347\u6811\u7684\u7b97\u6cd5\u7cfb\u5217\uff0c\u56e0\u6b64\u7814\u7a76\u5f97\u4ee5\u83b7\u5f97\u7279\u5f81\u91cd\u8981\u6027\u5206\u6570\uff0c\u5176\u4e2d\u5305\u542b\u6709\u5173\u7279\u5f81\u63cf\u8ff0\u7b26\u5bf9\u533a\u5206\u7c7b\u66f4\u6709\u7528\u7684\u4fe1\u606f\u3002<\/p>\n<p><strong>\u771f\u5b9e\u6570\u636e\u96c6\u7684\u5e94\u7528<\/strong><\/p>\n<p>\u56e2\u961f\u5728 6 \u4e2a Tara Oceans \u5b8f\u57fa\u56e0\u7ec4\u548c\u5143\u8f6c\u5f55\u7ec4\u6570\u636e\u96c6\u4e0a\u5e94\u7528\u4e86\u8be5\u9884\u6d4b\u5de5\u5177\u3002\u5728\u7ec4\u5408\u6570\u636e\u96c6\u4e2d\u53d1\u73b0\u7684 46,775,154 \u79cd\u603b\u86cb\u767d\u8d28\u4e2d\uff0c73% \u7684\u5e8f\u5217\u5c5e\u4e8e\u7ec6\u83cc\u57fa\u56e0\uff0c8% \u5c5e\u4e8e\u75c5\u6bd2\u57fa\u56e0\uff0c3% \u5c5e\u4e8e\u53e4\u7ec6\u83cc\u57fa\u56e0\uff0c\u5176\u4f59\u7684\u6ca1\u6709\u5206\u7c7b\u5b66\u5206\u7c7b\u3002<\/p>\n<p>\u5927\u7ea6 15.7% \u7684\u86cb\u767d\u8d28\u901a\u8fc7\u624b\u52a8\u5206\u7c7b\u88ab\u5f52\u7c7b\u4e3a\u8de8\u819c\u86cb\u767d\u3002\u5728\u5176\u4f59\u86cb\u767d\u8d28\u4e2d\uff0c65.2% \u88ab\u5f52\u7c7b\u4e3a\u7ec6\u80de\u8d28\u86cb\u767d\u8d28\uff0c\u800c 12.5% \u7684\u86cb\u767d\u8d28\u88ab\u5f52\u7c7b\u4e3a\u975e\u7ec6\u80de\u8d28\u86cb\u767d\u8d28\uff085.5% \u7ec6\u80de\u5916\uff0c7.0% \u5468\u8d28\u86cb\u767d\u8d28\uff09\u3002\u5269\u4f59\u5219\u672a\u88ab\u5f52\u5f55\u3002<\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-e44ab627a8a5cdae23d3b33f77758109.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" 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