{"id":40069,"date":"2025-04-11T22:02:41","date_gmt":"2025-04-11T14:02:41","guid":{"rendered":"https:\/\/17aitech.com\/?p=40069"},"modified":"2025-04-11T22:02:41","modified_gmt":"2025-04-11T14:02:41","slug":"%e5%8f%ac%e5%9b%9e%e7%8e%8798-5%ef%bc%8c%e5%bc%80%e6%ba%90%e6%b7%b7%e5%90%88%e5%ad%a6%e4%b9%a0%e7%b3%bb%e7%bb%9f%e7%b2%be%e5%87%86%e9%a2%84%e6%b5%8b%e7%94%9f%e7%89%a9%e5%a4%a7%e5%88%86%e5%ad%90","status":"publish","type":"post","link":"https:\/\/17aitech.com\/?p=40069","title":{"rendered":"\u53ec\u56de\u738798.5%\uff0c\u5f00\u6e90\u6df7\u5408\u5b66\u4e60\u7cfb\u7edf\u7cbe\u51c6\u9884\u6d4b\u751f\u7269\u5927\u5206\u5b50\u4e2d\u91d1\u5c5e\u7ed3\u5408\u4f4d\u70b9"},"content":{"rendered":"<p>\u6587\u7ae0\u6765\u6e90\u4e8e\u4e92\u8054\u7f51:<a href=\"https:\/\/www.jiqizhixin.com\/articles\/2025-04-11-6\" target=\"_blank\">\u53ec\u56de\u738798.5%\uff0c\u5f00\u6e90\u6df7\u5408\u5b66\u4e60\u7cfb\u7edf\u7cbe\u51c6\u9884\u6d4b\u751f\u7269\u5927\u5206\u5b50\u4e2d\u91d1\u5c5e\u7ed3\u5408\u4f4d\u70b9<\/a><\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-04fc251f6c2587c3a5662169ba4152cb.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-04fc251f6c2587c3a5662169ba4152cb.png\"><\/a><\/section>\n<p data-pm-slice=\"0 0 []\">\u7f16\u8f91\u4e28&amp;<\/p>\n<p>\u91d1\u5c5e\u79bb\u5b50\u662f\u8bb8\u591a\u86cb\u767d\u8d28\u4e2d\u7528\u4e8e\u86cb\u767d\u8d28\u529f\u80fd\u63a8\u65ad\u548c\u5de5\u7a0b\u5316\u7684\u91cd\u8981\u6210\u5206\uff0c\u5176\u590d\u6742\u6027\u4e0e\u7ed3\u6784\u50ac\u5316\u7b49\u4f5c\u7528\u6709\u5173\u3002\u73b0\u5982\u4eca\u7684\u6280\u672f\u5728\u5e94\u5bf9\u8fc7\u6e21\u91d1\u5c5e\u79bb\u5b50\u7684\u5efa\u6a21\uff0c\u7279\u522b\u662f\u5728\u77ac\u65f6\u3001\u53ef\u9006\u548c\u6d53\u5ea6\u4f9d\u8d56\u6027\u8c03\u8282\u4f4d\u70b9\u7b49\u96be\u9898\u65f6\uff0c\u663e\u5f97\u6709\u4e9b\u4e4f\u529b\u3002<\/p>\n<p>\u6c55\u5934\u5927\u5b66\u533b\u5b66\u9662\u3001\u6e56\u5357\u5927\u5b66\u4e0e\u7f8e\u56fd\u5f17\u5409\u5c3c\u4e9a\u5927\u5b66\uff08University of Virginia\uff09\u5e26\u6765\u4e86\u4e00\u79cd\u6df7\u5408\u673a\u5668\u5b66\u4e60\u7cfb\u7edf\uff0c\u540d\u4e3a PinMyMetal\uff08PMM\uff09\u3002\u8fd9\u4e2a\u7cfb\u7edf\u65e8\u5728\u51c6\u786e\u9884\u6d4b\u751f\u7269\u5927\u5206\u5b50\u4e2d\u7684\u8fc7\u6e21\u91d1\u5c5e\u5b9a\u4f4d\u548c\u73af\u5883\uff0c\u9002\u7528\u4e8e\u56db\u9762\u4f53\u548c\u516b\u9762\u4f53\u51e0\u4f55\u5f62\u72b6\u3002<\/p>\n<p>PMM \u4f18\u4e8e\u5176\u4ed6\u9884\u6d4b\u56e0\u5b50\uff0c\u5728\u914d\u4f53\u548c\u5750\u6807\u9884\u6d4b\u65b9\u9762\u5b9e\u73b0\u4e86\u5f88\u9ad8\u7684\u51c6\u786e\u6027\u3002\u5b83\u64c5\u957f\u9884\u6d4b\u8c03\u8282\u4f4d\u70b9\uff08\u4e2d\u4f4d\u504f\u5dee 0.36 \u00c5\uff09\uff0c\u5728\u5b9a\u4f4d\u50ac\u5316\u4f4d\u70b9\uff080.33 \u00c5\uff09\u548c\u7ed3\u6784\u4f4d\u70b9\uff080.19 \u00c5\uff09\u65b9\u9762\u8868\u73b0\u51fa\u5353\u8d8a\u7684\u51c6\u786e\u6027\u3002<\/p>\n<p>\u8be5\u7814\u7a76\u4ee5\u300cPinMyMetal: a hybrid learning system to accurately model transition metal binding sites in macromolecules\u300d\u4e3a\u9898\uff0c\u4e8e 2025 \u5e74 3 \u6708 28 \u65e5\u520a\u767b\u4e8e\u300aNature Communications\u300b\u3002<\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-1e4489f0195bb0c085525fa8499b03d7.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-1e4489f0195bb0c085525fa8499b03d7.png\"><\/a><\/section>\n<p><strong>\u6a21\u578b\u4f7f\u7528\u4e0e\u6d4b\u8bd5<\/strong><\/p>\n<p>PMM \u7cfb\u7edf\u91c7\u7528\u6df7\u5408\u5b66\u4e60\u65b9\u6cd5\uff0c\u6839\u636e\u4e0d\u540c\u7684\u51e0\u4f55\u5f62\u72b6\u6765\u8bc6\u522b MBS\u3002\u5bf9\u4e8e\u56db\u9762\u4f53\u914d\u4f4d\uff0c\u8be5\u7b97\u6cd5\u4f7f\u7528\u57fa\u4e8e CH \u7684\u65b9\u6cd5\uff0c\u4e13\u6ce8\u4e8e C \u548c H \u6b8b\u57fa\uff0c\u800c\u5bf9\u4e8e\u516b\u9762\u4f53\u914d\u4f4d\uff0c\u5b83\u91c7\u7528\u57fa\u4e8e EDH \u7684\u65b9\u6cd5\uff0c\u8003\u8651 E\u3001D \u548c H 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\u7684\u5019\u9009\u7ad9\u70b9\u5206\u914d\u786e\u5b9a\u6027\u5206\u6570\u3002\u5bf9\u524d\u8005\u91c7\u7528\u4e86\u4e24\u4e2a\u72ec\u7acb\u7684\u96c6\u6210\u5b66\u4e60\u6a21\u578b\uff0c\u5206\u522b\u68c0\u6d4b CH \u7ad9\u70b9\u4e0e EDH \u7ad9\u70b9\uff1b\u5bf9\u540e\u8005\u5219\u8ba1\u7b97\u5176\u9884\u6d4b\u4f4d\u70b9\u66f2\u7ebf\u4e0e\u76f8\u540c\u7b97\u6cd5\u5bf9\u51fd\u6570\u503c C \u7684\u76f8\u5e94\u6807\u51c6\u66f2\u7ebf\u4e4b\u95f4\u7279\u6b8a\u7cfb\u6570\u7684\u5e73\u5747\u503c\u3002<\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-cc12a4e5a644c657843e5a1bff13dd39.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-cc12a4e5a644c657843e5a1bff13dd39.png\"><\/a><\/section>\n<p>\u56fe\u793a\uff1a\u9884\u6d4b\u4f4e\u914d\u4f4d CH \u548c EDH 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MBS\uff0c\u5e76\u6210\u529f\u9884\u6d4b\u4e86\u7531\u6b8b\u57fa C670\u3001C667\u3001C685 \u548c C688 \u534f\u8c03\u7684\u950c\u7ed3\u5408\u4f4d\u70b9\uff0c\u4e0e\u5b9e\u9a8c\u786e\u5b9a\u7684\u4f4d\u70b9\u7684\u6700\u5c0f\u8ddd\u79bb\u504f\u5dee\u4e3a 0.025 \u00c5\u3002<\/p>\n<section><a href=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-00a03d199735faf147fc131b4e6e289d.png\" data-fancybox=\"images\" data-fancybox=\"gallery\"><img decoding=\"async\" src=\"https:\/\/17aitech.com\/wp-content\/uploads\/2025\/04\/frc-00a03d199735faf147fc131b4e6e289d.png\"><\/a><\/section>\n<p>\u56fe\u793a\uff1aPMM \u9884\u6d4b\u7684\u950c\u7ed3\u5408\u4f4d\u70b9\u3002\uff08\u56fe\u6e90\uff1a\u8bba\u6587\uff09<\/p>\n<p><strong>\u76f8\u8f83\u4e8e\u5176\u4ed6\u9884\u6d4b\u53d8\u91cf<\/strong><\/p>\n<p>PMM \u4e0e\u5176\u4ed6 MBS 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